98%
921
2 minutes
20
Objective: To introduce a new 3D magnetic resonance neurography (MRN) method involving a paramagnetic contrast-based T2 effect coupled with an advanced 3D heavily T2W SPACE-STIR high resolution imaging sequence that would enhance the contrast between nervous tissue and surrounding tissues.
Methods: Thirty subjects (average age, 39.6±17.0 years; 18 male and 12 female) were enrolled, including three patients with brachial plexopathy and 27 healthy volunteers. Subjective scores from two neuroradiologists, evaluating noncontrast MRN (cMRN) and 3D SPACE-STIR contrast enhanced MRN (ceMRN) 3D data using a 3-point scoring system, were compared using Wilcoxon signed-rank test. Contrast-to-noise ratios (CNRs), SNRs, and contrast ratios within the brachial plexus on cMRN vs. ceMRN MIP and source images were also compared using the paired t-test.
Results: The average score for cMRN (0.77±0.43) was significantly lower than ceMRN (1.73±0.45) (p<0.001). Lower nerve vs. vein CNRs were found on cMRN vs. ceMRN, respectively (p<0.001 for both source and MIP images). All nerve-to-surrounding tissue contrast ratios (i.e., fat, muscle, veins, and bone) were higher for ceMRN compared with cMRN for both source and MIP images (all p<0.05).
Conclusion: The improved 3D visualization of the brachial plexus and its branches, using this new contrast-enhanced MRN method, can provide high resolution imaging which may be of significant value in the assessment of brachial plexopathy.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.1016/j.ejrad.2015.12.001 | DOI Listing |
Clin Neurol Neurosurg
October 2022
Department of General and Interventional Radiology and Neuroradiology, Wroclaw Medical University, Wroclaw, Poland. Electronic address:
Susceptibility weighted imaging (SWI) has been broadly incorporated to MR protocols as it provides unique additional diagnostic information in a wide variety of neurological conditions. SWI exploits local field inhomogeneities created by various paramagnetics (deoxyhaemoglobin, blood breakdown products), diamagnetics (calcium) or oxygenated blood, hereby provides contrast based on magnetic susceptibility. In this review we present various examples from everyday clinical practice including, among others, acute stroke, neurodegenerative disorders, haemorrhagic lesions, vascular malformations, mycotic intracranial aneurysm, primary central nervous system vasculitis, neoplasms in which SWI was essential for diagnosis.
View Article and Find Full Text PDFFront Phys
June 2020
Adámas Nanotechnologies, Inc., Raleigh, NC, United States.
Fluorescence of the negatively charged nitrogen-vacancy (NV) center of diamond is sensitive to external electromagnetic fields, lattice strain, and temperature due to the unique triplet configuration of its spin states. Their use in particulate diamond allows for the possibility of localized sensing and magnetic-contrast-based differential imaging in complex environments with high fluorescent background. However, current methods of NV production in diamond particles are accompanied by the formation of a large number of parasitic defects and lattice distortions resulting in deterioration of the NV performance.
View Article and Find Full Text PDFEur J Radiol
March 2016
Department of Radiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China. Electronic address:
Objective: To introduce a new 3D magnetic resonance neurography (MRN) method involving a paramagnetic contrast-based T2 effect coupled with an advanced 3D heavily T2W SPACE-STIR high resolution imaging sequence that would enhance the contrast between nervous tissue and surrounding tissues.
Methods: Thirty subjects (average age, 39.6±17.
Exp Ther Med
May 2015
Ministry of Education Key Laboratory of Macromolecular Synthesis and Functionalization, Department of Polymer Science and Engineering, Zhejiang University, Hangzhou, Zhejiang 310027, P.R. China.
Europium (Eu) is a paramagnetic lanthanide element that possesses an outstanding luminescent property. Eu complexes are ideal fluorescence imaging (FI) agents. Eu has satisfactory relaxivity and optical properties, and can realize magnetic resonance (MRI)-FI dual imaging applications when used with appropriate cryptands that render it oxidatively stable.
View Article and Find Full Text PDFChempluschem
May 2012
Department of Radiology, The University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd., Dallas, Texas 75390-9058, USA.
There is increasing interest in the development of reporter agents to reveal enzyme activity using small animal imaging. We have previously demonstrated the feasibility of detecting gene activity using the commercially available 3,4-cyclohexenoesculetin-β--galactopyranoside (S-Gal™) as a H MRI reporter. Specifically, β-galactosidase (β-gal) releases the aglycone, which forms an MR contrast-inducing paramagnetic precipitate in the presence of Fe.
View Article and Find Full Text PDF