Synthesis at the Speed of Codons.

Trends Biochem Sci

Department of Molecular Biology and Genetics, Johns Hopkins School of Medicine, Baltimore, MD, USA. Electronic address:

Published: December 2015


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Article Abstract

The possibility that different mRNA sequences encoding identical peptides are translated dissimilarly has long been of great interest. Recent work by Yu and co-workers provides striking evidence that mRNA sequences influence the rate of protein synthesis, and lends support to the emerging idea that mRNA sequence informs protein folding.

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http://dx.doi.org/10.1016/j.tibs.2015.10.005DOI Listing

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