DNA-caged gold nanoparticles for controlled release of doxorubicin triggered by a DNA enzyme and pH.

Chem Commun (Camb)

School of Chemistry and Chemical Engineering, Southeast University, Jiangning, Nanjing, Jiangsu 211189, P. R. China.

Published: August 2015


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Article Abstract

DNA polyhedron-caged gold nanoparticles (AuNP) were self-assembled using four-point-star DNAs, with three strands hybridizing to each other and the fourth strand attaching to the AuNPs. The DNA-caged AuNPs can work as nanocarriers for doxorubicin, and controlled release behaviour can be triggered by both a DNA enzyme and by the pH value.

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http://dx.doi.org/10.1039/c5cc05164aDOI Listing

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