Reversible thermo-sensitivity induced from varying the hydrogen bonding between the side residues of rationally designed polypeptides.

Chem Commun (Camb)

Key Laboratory of Advanced Polymeric Materials, School of Materials Science and Engineering, East China University of Science and Technology, 130 Meilong Road, Shanghai 200237, P. R. China.

Published: June 2015


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Article Abstract

Rationally designed polypeptides with similar molecular structures but varying patterns of hydrogen bonding between the side groups have been synthesized and demonstrated to possess distinct solubility and thermal behaviors. Further balancing the ratio of both isopropylamine and ethylenediamine side groups endows the random copolymer with reversible thermo-sensitivity.

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http://dx.doi.org/10.1039/c5cc03017jDOI Listing

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