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A recently introduced structure for the capacitive micromachined ultrasonic transducers (CMUTs) has focused on the applications of the asymmetric mode of vibration and has shown promising results in construction of super-resolution ultrasound images. This paper presents the first implementation and experimental results of a transceiver circuit to interface such CMUT structures. The multiple input/multiple output receiver in this work supports both fundamental and asymmetric modes of operation and includes transimpedance amplifiers and low-power variable-gain stages. These circuit blocks are designed considering the trade-offs between gain, input impedance, noise, linearity and power consumption. The high-voltage transmitter can generate pulse voltages up to 60 V while occupying a considerably small area. The overall circuit is designed and laid out in a 0.35 μm CMOS process and a four-channel transceiver occupies 0.86 × 0.38 mm(2). The prototype chip is characterized in both electrical and mechanical domains. Measurement results show that each receiver channel has a nominal gain of 110 dBΩ with a 3 dB bandwidth of 9 MHz while consuming 1.02 mW from a 3.3 V supply. The receiver is also highly linear, with 1 dB compression point of minimum 1.05 V which is considerably higher than the previously reported designs. The transmitter consumes 98.1 mW from a 30 V supply while generating 1.38 MHz, 30 V pulses. The CMOS-CMUT system is tested in the transmit mode and shows full functionality in air medium.
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http://dx.doi.org/10.1109/TBCAS.2015.2406777 | DOI Listing |
Eur Radiol Exp
September 2025
Center for MR-Research, University Children's Hospital Zurich, University of Zurich, Zurich, Switzerland.
Background: Fetal MRI is increasingly used to investigate fetal lung pathologies, and super-resolution (SR) algorithms could be a powerful clinical tool for this assessment. Our goal was to investigate whether SR reconstructions result in an improved agreement in lung volume measurements determined by different raters, also known as inter-rater reliability.
Materials And Methods: In this single-center retrospective study, fetal lung volumes calculated from both SR reconstructions and the original images were analyzed.
Ultrasonics
August 2025
College of Biomedical Engineering, Fudan University, Shanghai 200438, China; State Key Laboratory of Integrated Chips and Systems, Fudan University, Shanghai 200438, China; Poda Medical Technology Co., Ltd., Shanghai 200433, China. Electronic address:
Transcranial ultrasound localization microscopy (t-ULM) is faced with challenges posed by the skull, including acoustic attenuation and phase aberrations. There is a significant request for an efficient aberration correction method achieving a great balance between computational complexity and accuracy. In this study, the ray theory is first applied to in-vivo transcranial imaging to calculate the traveltime table in the inhomogeneous medium model of the imaging region.
View Article and Find Full Text PDFTalanta
August 2025
School of Public Health &Jiangxi Provincial Key Laboratory of Disease Prevention and Public Health, Jiangxi Medical College, Nanchang University, Nanchang, Jiangxi, 330031, PR China. Electronic address:
Hemorrhagic fever with renal syndrome (HFRS), caused by Hantaan virus, poses a serious public health threat. Current diagnostic methods remain limited by low sensitivity, complex procedures, and high sample requirements. To address this, we developed a highly sensitive single-molecule biosensor using multi-fluorophore nucleic acid probes and STORM imaging for the detection of Hantaan virus RNA.
View Article and Find Full Text PDFMed Phys
August 2025
Department of Nuclear Medicine, Affiliated Hospital of Nantong University, Nantong, JiangSu, China.
Background: Super-resolution (SR) reconstruction-based positron emission tomography (PET) imaging has been widely applied in the field of computer vision. However, their definitive clinical benefits have yet to be validated. Radiomics-based modeling provides an effective approach to evaluate the clinical utility of SRPET imaging.
View Article and Find Full Text PDFCancer Biother Radiopharm
September 2025
Department of Critical Care Medicine, The First People's Hospital of Jiande, Hangzhou city, China.
Oncologic emergencies in critically ill cancer patients frequently require rapid, real-time assessment of tumor responses to therapeutic interventions. However, conventional imaging modalities such as computed tomography and magnetic resonance imaging are often impractical in intensive care units (ICUs) due to logistical constraints and patient instability. Super-resolution ultrasound (SR-US) imaging has emerged as a promising noninvasive alternative, facilitating bedside evaluation of tumor microvascular dynamics with exceptional spatial resolution.
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