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Article Abstract
In this study HIV-1 subtype C-infected adults demonstrated higher purifying selection on their viral populations in reverse transcriptase (RT) than infected children. This difference is likely explained by more mature cytotoxic T-lymphocyte responses in adults, which may have implications for the development of drug resistance in the RT region.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4458742 | PMC |
| http://dx.doi.org/10.1089/AID.2015.0023 | DOI Listing |
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