98%
921
2 minutes
20
Although directed to the control of allergic symptoms, a possible effect of sublingual immunotherapy (SLIT) on susceptibility to infections has been hypothesized. Two hundred sixty-five children aged between 3 and 4 years of age affected by allergic rhinitis completed a 6 year prospective case-control study. One hundred forty-three children after 2 years of SLIT reported a lower prevalence of respiratory tract infections when compared to children not undergoing SLIT.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.1185/03007995.2015.1027182 | DOI Listing |
Am J Otolaryngol
May 2025
Department of Otorhinolaryngology Head and Neck Surgery, Hainan Affiliated Hospital of Hainan Medical University, Hainan General Hospital, Haikou, Hainan, China. Electronic address:
Background: Sublingual immunotherapy (SLIT) has been widely established as a disease-modifying treatment for allergic airway diseases. However, its efficacy and safety in allergic pharyngitis (AP) remain insufficiently investigated and require further clinical validation.
Methods: In this retrospective study, 100 patients diagnosed with house dust mite (HDM)-induced AP concomitant with allergic rhinitis (AR) were enrolled.
Pharmaceutics
August 2025
Department of Pharmaceutical Sciences, University of Tennessee Health Science Center, 881 Madison Ave, Rm 661, Memphis, TN 38018, USA.
In this review, our intention was to shed some light on the history of sublingual and buccal delivery over the past 75 years. By searching the query sublingual and buccal, we noticed four steady growth periods in the number of publications between 1950 and 2025. The early phase of sublingual and buccal drug delivery (1950-1982) saw limited attempts to explore this delivery route.
View Article and Find Full Text PDFFront Allergy
July 2025
Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, Italy.
[This corrects the article DOI: 10.3389/falgy.2025.
View Article and Find Full Text PDFJ Food Allergy
August 2024
From the Department of Pediatrics, University of North Carolina School of Medicine, Chapel Hill, North Carolina and.
Background: Peanut allergy remains a common problem that persists into adulthood for most patients, with risks of accidental ingestion and poor quality of life. Oral immunotherapy (OIT) and anti-immunoglobulin E (IgE) therapy are effective options for peanut allergy; however, each therapy has limitations, which makes them not ideal for all patients.
Objective: The objective was to summarize recent studies that support sublingual immunotherapy (SLIT) for peanut allergy as an alternative option to OIT and anti-IgE therapy, and to discuss practical considerations for its use in clinical practice.
J Food Allergy
August 2024
From the Section of Immunology, Allergy and Retrovirology, Department of Pediatrics, Texas Children's Hospital, Houston, Texas and.
Background: Food allergies pose a significant burden on the daily life of individuals with food allergy, including dietary, psychosocial, and economic impact. The management of food allergy has shifted recently from previous passive avoidance approaches to current active therapeutic interventions.
Objective: This article aims to discuss selection of patients with food allergies for different therapies.