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A new interpenetrated bioactive nonlinear optical metal-organic framework [Zn2(ppa)2(1,3-bdc)(H2O)] has been designed and synthesized, which shows both a high drug content of 63.9% and a good slow release effect in simulated physical conditions compared to other non-interpenetrated bioactive MOFs. It also shows a large powder second-harmonic generation (SHG) efficiency of 5.6 times that of KH2PO4 (particle size: 150-200 μm).
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http://dx.doi.org/10.1039/c4dt02672a | DOI Listing |
Food Chem
August 2025
College of Food Science and Engineering, Shandong Agricultural University, Key Laboratory of Food Processing Technology and Quality Control of Shandong Higher Education Institutes, Taian 271018, PR China.. Electronic address:
Functional ingredient bioaccessibility is limited by instability and low solubility, thus, edible macromolecules are used to enhance delivery. This study presents a safe, sustainable method to prepare dual-network emulsion gel (CSEG). The gel is formed via Ca-induced crosslinking of sodium alginate (SA) and coffee cherry-derived polysaccharide (CCP) to enhance bioavailability.
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August 2025
School of Food Science, Northeast Agricultural University, Harbin, Heilongjiang 150030, China. Electronic address:
To investigate the effects of different material combinations and oil/water phase ratios on the physicochemical properties of bigels, gelatin-carboxymethyl chitosan-hydrogels and beeswax-oleogels were used for bigel formulation. Results showed that a gelatin-to-carboxymethyl chitosan ratio of 1:1, led to a dense interpenetrating network that enhanced hydrogel-oleogel interactions, resulting in superior water-holding capacity (86.01 %), oil-holding capacity (81.
View Article and Find Full Text PDFAdv Healthc Mater
July 2025
Complex Tissue Regeneration Department, MERLN Institute for Technology Inspired Regenerative Medicine, Maastricht University, Maastricht, 6229 ER, The Netherlands.
Collagen peptide (COP) is water soluble, bioactive, and tends to be a promising alternative to collagen for tissue regeneration. However, its low viscosity and lack of readily polymerizable groups hinder its bioprinting and limit its wide applications in tissue engineering. In this study, methacrylated collagen peptide-xanthan gum (COPMA-XG) bioinks with interpenetrating networks are developed for bioprinting stable constructs, followed by stem cell differentiation.
View Article and Find Full Text PDFACS Biomater Sci Eng
August 2025
Department of Bioengineering, University of Washington, Seattle, Washington 98105, United States.
Though recombinant protein therapeutics hold great potential in treating many diseases, their intravenous delivery introduces challenges with off-target effects and short circulation half-lives. Injectable biomaterial depots have proven useful in confining therapeutic administration to specific bodily locations but have faced difficulties in simultaneously controlling drug release, network mechanics, and functionalization. Toward addressing these limitations, this work introduces the first recombinant protein-based interpenetrating polymer network (IPN), which we exploit for injectable therapeutic deposition.
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November 2025
College of Enology, Northwest A & F University, Yangling 712100, Shaanxi, China; Shaanxi Engineering Research Center for Viti-Viniculture, Yangling 712100, Shaanxi, China. Electronic address:
Fresh fruits are highly favored by consumers due to their appealing flavor and rich nutritional value. However, significant postharvest losses occur due to physiological senescence and fungal pathogen infection. Therefore, it is imperative to develop high-performance, sustainable active coatings for postharvest fruit preservation.
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