Long Non-Coding RNAs Involved in Immune Responses.

Front Immunol

Radioisotope Centre, The University of Tokyo, Tokyo , Japan.

Published: November 2014


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Article Abstract

A large number of human RNA transcripts, which do not encode proteins are defined as non-coding RNAs (ncRNAs). These ncRNAs are divided into two classes of different lengths; short and long ncRNAs. MicroRNAs are a major class of short ncRNAs, ~22 nucleotides in length that regulate gene expression at the post-transcriptional level. Long non-coding RNAs (lncRNAs) are more than 200 nucleotides in length and play roles in various biological pathways. In this review, we summarize the functions of lncRNAs which regulate immune responses.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4230175PMC
http://dx.doi.org/10.3389/fimmu.2014.00573DOI Listing

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