98%
921
2 minutes
20
4-tert-Butyl-4'-methoxydibenzoylmethane (BMDM) is a widely used ultraviolet A filter. In this work, we have studied the effect of chlorine and dissolved organic matter (DOM) concentrations on the stability of UV filter (BMDM) present in two commercial sunscreen cream formulations in water. An experimental design was used to assess the effect of the two experimental factors on the degradation of BMDM. Higher concentrations of chlorine lead to higher degradation percentages of BMDM and higher concentrations of DOM inhibit its degradation. Moreover, a mono and a dichloro derivate of BMDM were identified as by-products.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.1080/09593330.2014.988184 | DOI Listing |
Inflammation
August 2025
Basic and Applied Immunology Program, Ribeirao Preto Medical School, University of Sao Paulo, 3900 Bandeirantes Ave., Ribeirao Preto, SP, Brazil.
The adipokine chemerin is increased in the serum of individuals with obesity and type 2 diabetes. Patients with type 2 diabetes exhibit a threefold increased risk of developing tuberculosis, are more refractory to tuberculosis treatment and display more severe forms of the disease. Patients with type 2 diabetes and tuberculosis exhibit a dysfunctional immunological response characterized by a higher frequency of peripheral Th1 and Th17 cells, increased concentrations of pro- and anti-inflammatory cytokines, and a reduced microbicidal capacity compared to subjects affected exclusively by tuberculosis.
View Article and Find Full Text PDFCells
June 2025
Department of Oral Science and Translational Research, College of Dental Medicine, Nova Southeastern University, 3301 South University Drive, Fort Lauderdale, FL 33314, USA.
Regulatory B cells (B regs) are immune cells that help suppress excessive inflammatory responses by interacting with other immune components. Among them, B-10 cells are known for their strong immunoregulatory function. This study focused on how B-10 cells influence macrophage phenotype and function through the PD-1 signaling pathway.
View Article and Find Full Text PDFCell Commun Signal
May 2025
Department of Nutritional Biochemistry, Institute of Nutritional Science, University of Potsdam, Nuthetal, Germany.
Background: The transition from metabolic dysfunction-associated steatotic liver disease (MASLD) to steatohepatitis (MASH) is characterized by a chronic low-grade inflammation, involving activation of resident macrophages (Kupffer cells; KC) and recruitment of infiltrating macrophages. Macrophages produce cytokines and, after induction of Cyclooxygenase 2 (COX-2), the key enzyme of prostanoid synthesis, prostaglandin E (PGE). PGE modulates cytokine production in an autocrine and paracrine manner, therefore playing a pivotal role in regulating inflammatory processes.
View Article and Find Full Text PDFPLoS Negl Trop Dis
May 2025
Jiangsu Key Laboratory of Immunity and Metabolism, Jiangsu International Key Laboratory of Immunity and Metabolism, National Demonstration Center for Experimental Basic Medical Science Education, Department of Pathogenic Biology and Immunology, School of Basic Medical Science, Xuzhou Medical Univers
During Clonorchis sinensis (C. sinensis) infection, pro-inflammatory macrophages (M1 macrophages) are highly activated, yet their role in the disease remains poorly understood. Previous studies have demonstrated that extracellular vesicles from C.
View Article and Find Full Text PDFBackground: Over 10 million patients undergoing non-cardiac surgery annually experience major cardiovascular complications within 30 days, many due to destabilized atherosclerotic plaques. Reverse cholesterol transport (RCT), a key pathway for cholesterol removal by HDL and apoA-I, is critical in preventing plaque progression. While surgery-induced inflammation is known to impair HDL function, its effects on RCT and plaque stability remain unclear.
View Article and Find Full Text PDF