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Development of experimental techniques for characterization of magnetic properties at high spatial resolution is essential for progress in miniaturization of magnetic devices, for example, in data storage media. Inelastic scattering of electron vortex beams (EVBs) was recently reported to contain atom-specific magnetic information. We develop a theoretical description of inelastic scattering of EVBs on crystals and perform simulations for EVBs of different diameters. We show that use of an EVB wider than an interatomic distance does not provide any advantage over an ordinary convergent beam without angular momentum. On the other hand, in the atomic-resolution limit, electron energy loss spectra measured by EVBs are strongly sensitive to the spin and orbital magnetic moments of studied matter, when channeling through or very close to the atomic columns. Our results demonstrate the boundaries for efficient use of EVBs in measurement of magnetic properties.
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http://dx.doi.org/10.1103/PhysRevLett.111.105504 | DOI Listing |
Nat Commun
September 2025
Institute of Neurosciences and Medicine, Brain & Behaviour (INM-7), Research Centre Juelich; Wilhelm-Johnen-Straße 1, Juelich, Germany.
Autism is a neurodevelopmental condition associated with altered resting-state brain function. An increased excitation-inhibition ratio is discussed as a pathomechanism but in-vivo evidence of disturbed neurotransmission underlying functional alterations remains scarce. We compare local resting-state brain activity and neurotransmitter co-localizations between autism (N = 405, N = 395) and neurotypical controls (N = 473, N = 474) in two independent cohorts and correlate them with excitation-inhibition changes induced by glutamatergic (ketamine) and GABAergic (midazolam) medication.
View Article and Find Full Text PDFNeurotoxicology
September 2025
Department of Otolaryngology Head and Neck Surgery, The Third People's Hospital of Chengdu, The Affiliated Hospital of Southwest Jiaotong University, Chengdu 610031, China. Electronic address:
Gadolinium-based contrast agents (GBCAs) are widely used in systemic magnetic resonance imaging (MRI) and can be employed in otology to evaluate endolymphatic hydrops in patients with Ménière's disease. Given the heavy metal properties of gadolinium and its tendency to deposit in tissues, it is essential to assess its ototoxic risk. We evaluated the ototoxicity of gadodiamide using in vitro and in vivo models.
View Article and Find Full Text PDFNeurosci Lett
September 2025
Institute of Neuroscience & Department of Physiology, Hengyang Medical School, University of South China, Hengyang 421001 Hunan, PR China; NHC Key Laboratory of Neurodegenerative Disease (University of South China), Hengyang 421001 Hunan, PR China; The Second Affiliated Hospital, Brain Disease Resea
Radiation-induced brain injury (RIBI) is a prevalent complication following radiotherapy for head and neck tumors, and its effective therapeutic strategies are lacking. Ferroptosis, an iron-dependent cell death, has recently emerged as an important mechanism of radiation-induced cell death. Repetitive transcranial magnetic stimulation (rTMS) is a noninvasive neuro-interventional technique with antioxidant and neuroprotective properties.
View Article and Find Full Text PDFInt J Biol Macromol
September 2025
College of Textiles, Donghua University, Shanghai, 201620, China; Key Laboratory of Textile Science & Technology, Ministry of Education, Donghua University, Shanghai, 201620, China. Electronic address:
In this study, a novel bleaching method for ramie cellulose fibers with low oxidative damage was developed by utilizing the properties of sodium percarbonate contained in tea saponin, which slowly releases hydrogen peroxide in the catalytic oxidation system of N-hydroxyphthalimide (NHPI). First, the bleaching process was optimized using response surface design, followed by comparison and characterization of fiber properties prepared under different bleaching systems. Finally, the energy consumption, water consumption, and toxicity of the NHPI/tea saponin system were evaluated.
View Article and Find Full Text PDFJ Colloid Interface Sci
September 2025
School of Materials, Shenzhen Campus of Sun Yat-sen University, Shenzhen 518107, China. Electronic address:
Harnessing the significant buildup of lactic acid (LA) within the tumor microenvironment (TME) for metabolic manipulation presents a promising avenue for cancer treatment. Nevertheless, single-agent therapies often fail to address the complex and varying needs of TME heterogeneity, posing a substantial scientific hurdle in oncology. In this context, we employ asymmetric mesoporous silica nanoparticles (AMS NPs) as delivery vehicles, simultaneously loading them with zinc‑cobalt‑manganese ferrite nanoparticles (ZCMF NPs), lactate oxidase (LOX), and doxorubicin (DOX).
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