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Purpose: To systematically evaluate implant success rates with different loading protocols.
Materials And Methods: A search was conducted of electronic databases, including The Cochrane Oral Health Group's Trials Register, PubMed, SciSearch, Medline, and EMBASE, for all randomized controlled trials published between 1997 and 2011 to compare implant success rates among different loading methods. The quality of randomized controlled trials was critically appraised, and the data were extracted by two independent reviewers. Meta-analyses were conducted of the eligible randomized controlled trials.
Results: A total of 26 randomized controlled trials met the criteria for meta-analysis. The quality of these articles was moderate. Eight trials compared immediate and early loading (relative risk [RR] = 0.90, 95% confidence interval [CI] 0.42-1.93, P = .79), 7 compared early with delayed loading (RR = 1.19, 95% CI 0.52-2.72, P = .69), and 11 compared immediate and delayed loading (RR = 1.19, 95% CI 0.52-2.72, P = .69).
Conclusions: The limited evidence shows that there is no significant difference in implant success rates with different loading protocols.
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http://dx.doi.org/10.11607/jomi.2712 | DOI Listing |
J Cardiovasc Surg (Torino)
September 2025
Catheterization Laboratory, Montevergine Clinic, Mercogliano, Avellino, Italy -
Background: Lower extremity arterial disease is a prevalent vascular condition leading to ischemic symptoms and increased risk of cardiovascular events. Drug-eluting stents have improved outcomes by reducing restenosis, with sirolimus emerging as a promising alternative to paclitaxel due to its safer profile. This study evaluates the efficacy and safety of novel polymer-free Amphilimus formulation (Sirolimus + fatty acid) eluting self-expanding stent in the treatment of femoropopliteal disease in a real-world population.
View Article and Find Full Text PDFLaryngoscope
September 2025
Buckingham Center for Facial Plastic Surgery, Austin, Texas, USA.
Hypoglossal nerve stimulation (HNS) device placement for moderate to severe obstructive sleep apnea has been growing in popularity. The incidence of patients requesting cervical rhytidectomy following implant placement is likely to increase proportionally to the incidence of device placement. This case report describes the preoperative and introperative considerations and details of successful rhytidectomy with platysmaplasty surgery with previous HNS device placement.
View Article and Find Full Text PDFAdv Healthc Mater
September 2025
Krembil Research Institute, Toronto Western Hospital, University Health Network, Toronto, ON, M5T 0S8, Canada.
Accurate brain signal recording and precise electrode placement are critical for the success of neuromodulation therapies such as deep brain stimulation (DBS). Addressing these challenges requires deep brain electrodes that provide high-quality, stable recordings while remaining compatible with high-resolution medical imaging modalities like magnetic resonance imaging (MRI). Moreover, such electrodes shall be cost-effective, easy to manufacture, and patient-compatible.
View Article and Find Full Text PDFFASEB J
September 2025
Faculty of Medicine in Pilsen, Biomedical Center, Charles University, Prague, Czech Republic.
Mitochondria in the egg are suggested to be crucial for the onset of new life. However, there is ambiguous knowledge about the necessity for fertilization and early embryonic development. Therefore, we created a conditional Tfam knockout (Tfam; Zp3-Cre) to produce Tfam oocytes for investigation of the mitochondrial abundance in oocytes and early embryos.
View Article and Find Full Text PDFVet Surg
September 2025
Rainbow Equine Hospital, Malton, UK.
Objective: To describe the surgical approach used in horses undergoing C7-T1 ventral interbody fusion using a kerf cut cylinder (KCC) implant and report the short- and long-term outcomes.
Study Design: Observational retrospective study.
Animals: A total of 38 client-owned horses.