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We report the case of a 61-year-old female with advanced gastric cancer and mediastinal lymph node metastasis who developed chylothorax. The patient presented with cough, dyspnea and pain in the left lower limb, back, and hips. Her lower limb symptoms were attributed to cellulitis. Computed tomography revealed right-sided pleural effusion, multiple lymph node swelling, and thickening of the gastric wall. Following pleural aspiration, the effusion was identified to be chyle. Cytopathologically, numerous adenocarcinoma cells were detected in clumps, and subsequent esophagogastroduodenoscopy revealed type 3 gastric cancer. We diagnosed multiple lymph node metastases with pleural dissemination. Chemotherapy was administered; however, she eventually succumbed to disease progression. We suspected that the chylothorax resulted from the mediastinal lymph node metastasis that caused thoracic duct obstruction.
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Int J Surg
September 2025
Guangxi Medical University, Nanning, Guangxi, China.
Ann Nucl Med
September 2025
Department of Nuclear Medicine, Marmara University School of Medicine, Istanbul, Turkey.
Objective: This study aims to systematically evaluate the inter- and intra-observer agreement regarding lesions with uncertain malignancy potential in Ga-68 PSMA PET/CT imaging of prostate cancer patients, utilizing the PSMA-RADS 2.0 classification system, and to emphasize the malignancy evidence associated with these lesions.
Methods: We retrospectively reviewed Ga-68 PSMA PET/CT images of patients diagnosed with prostate cancer via histopathology between December 2016 and November 2023.
Ann Surg Oncol
September 2025
Cancer Center, Renmin Hospital of Wuhan University, Wuhan, China.
Background: The optimal number of examined lymph nodes (ELN) for accurate staging and prognosis for esophageal cancer patients receiving neoadjuvant therapy remains controversial. This study aimed to evaluate the impact of ELN count on pathologic staging and survival outcomes and to develop a predictive model for lymph node positivity in this patient population.
Methods: Data were extracted from the Surveillance, Epidemiology, and End Results (SEER) database and a multicenter cohort.
Int J Surg
September 2025
Department of Gastrointestinal Surgery, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, Shandong, China.
Aim And Background: This study investigates the impact of D3 lymph node dissection extent on postoperative bowel function and nutritional status in patients undergoing radical surgery for right-sided colon cancer. Given that postoperative diarrhea can significantly affect the quality of life, we examined whether dissection boundaries influence these outcomes.
Methods: This was a prospective, randomized controlled trial conducted at a high-volume tertiary hospital.
AJR Am J Roentgenol
September 2025
Professor, Department of Radiology, Division of Abdominal Radiology University of Michigan and Michigan Medicine.
Mid-field (0.55-T) MRI may offer an alternative to higher field strengths for pancreatic intraductal papillary mucinous neoplasms (IPMNs) surveillance given high-quality MRCP sequences enabled by longer T2 relaxation times and greater patient comfort resulting from a larger bore and reduced acoustic noise. However, SNR is lower at 0.
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