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Systematic review of pro-equity strategies to improve vaccination among priority populations.
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Sydney School of Public Health, Faculty of Medicine and Health, The University of Sydney, New South Wales, Australia; Sydney Infectious Diseases Institute, Faculty of Medicine and Health, The University of Sydney, New South Wales, Australia. Electronic address:
Background/objectives: The importance of pro-equity strategies in addressing disadvantages that people and communities face due to their gender, migration status, ethnicity, disability, and place of residence is increasingly being recognised, but analysis of empirical evidence on how they improve vaccination in these priority groups is limited. This systematic review aims to fill this gap.
Methods: Standard evidence synthesis methods were employed, with searches conducted in four major bibliographic databases in March 2025.
An Overview on Lipid Nanocapsules: Exploring the Role in Precision Cancer Treatment and Lymphatic Drug Distribution.
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Department of Pharmaceutics, Manipal College of Pharmaceutical Sciences, Manipal Academy of Higher Education, Manipal 576104, India.
Lipid nanocapsules (LNCs) are an emerging nanocarrier platform for cancer therapy as they can co-deliver multiple drugs, promote synergistic action, and provide targeted drug delivery. The phase inversion temperature (PIT) process is most used for LNC formulation, which has the advantage of process simplicity, thermodynamic stability, and the employment of non-toxic solvents without requiring high energy input. Surface functionalization with targeting ligands like folic acid and peptides increases tumor specificity and reduces off-target toxicity.
View Article and Find Full Text PDFLow-level tetrabromobisphenol a (TBBPA) exposure disrupts early embryonic architecture: molecular impacts on dorsoventral patterning.
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Department of Biological Sciences, Clemson University, Clemson, SC, USA; Clemson University Center for Human Genetics, Greenwood, SC, USA. Electronic address:
Tetrabromobisphenol A (TBBPA), a widely used flame retardant in textiles and electronics, poses toxicological risks through both environmental and indoor exposures. Biomonitoring studies have detected significant TBBPA levels in prenatal environments, including cord blood, raising concerns about developmental impacts. Using zebrafish as a model, this study addresses critical gaps in understanding how developmental TBBPA exposures perturb regulatory pathways that govern dorsoventral patterning.
View Article and Find Full Text PDFExploring healthcare professionals' perceptions on implementing home hemodialysis and self-assisted hemodialysis: a qualitative explorative study.
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Division of Nursing, Singapore General Hospital, Singapore, Singapore.
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Spinal cord compression as the initial presentation of de novo metastatic testicular seminoma: A rare and complex case.
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Austin Health, Heidelberg, VIC, Australia.
We report a 43-year-old man with de novo metastatic testicular seminoma complicated by paraplegia from spinal cord compression due to retroperitoneal lymphadenopathy. Urgent retroperitoneal biopsy confirmed seminoma and, after the patient declined neurosurgical intervention, systemic chemotherapy was promptly initiated prior to delayed orchidectomy. Post-chemotherapy orchidectomy histology revealed minimal viable tumour and serial imaging showed a residual retroperitoneal mass with low-grade uptake on FDG-PET.
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