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Peritoneal dialysis (PD) as a therapy with all its advantages has not grown as would have been expected except in certain pockets, notably in Asia. In our opinion, from patient and their family interviews, a perception among prospective PD patients of inaccessibility to the referral PD Unit (RPU), usually for patients from rural areas in far flung places, inaccessible due to difficult terrain or long distances, play a strong role against the choice of PD as their modality choice for end-stage renal disease. We decided to address this issue by adopting novel initiatives such as easy access to the RPU through usage of internet and mobile phones from the patient homes especially in addressing the more clinically relevant infectious complications such as peritonitis and exit site infections with immediate treatment management responses from the RPU. In addition, we found that inherently the rural PD patients had several advantages over their urban counterparts and also over their hemodialysis (HD) counterparts in many socioeconomic, emotional support and nutritional parameters. We enhanced these advantages with an intensive home visit program. This two pronged approach has paid dividends in that our rural PD patients do as well, if not better than the urban PD and the HD patients, contrary to prevailing international experience.
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http://dx.doi.org/10.1159/000337816 | DOI Listing |
Clin J Am Soc Nephrol
September 2025
Nephrology and Hypertension, Vanderbilt University Medical Center, Nashville, TN, USA.
Clin J Am Soc Nephrol
September 2025
University College London Great Ormond Street Hospital for Children and Institute of Child Health, London, UK.
Background: Experience with icodextrin use in children on long-term peritoneal dialysis is limited. We describe international icodextrin prescription practices and their impact on clinical outcomes: ultrafiltration, blood pressure control, residual kidney function (RKF), technique and patient survival.
Methods: We included patients under 21 years enrolled in the International Pediatric Peritoneal Dialysis Network (IPPN) between 2007 and 2024, on automated PD with a daytime dwell.
JAMA Netw Open
September 2025
Department of Internal Medicine, University of Arkansas for Medical Sciences, Little Rock.
Importance: Patients with kidney failure (KF) receiving long-term dialysis have increased incidence of atrial fibrillation (AF). Patients with KF and AF have increased risk of stroke, death, and bleeding compared with age-matched cohorts. In KF, the use of oral anticoagulants (OACs) increases hemorrhage risk, offsetting potential benefits and making left atrial appendage occlusion (LAAO) a potentially promising solution for risk reduction in AF.
View Article and Find Full Text PDFG Ital Nefrol
August 2025
Nephrology, Dialysis and Transplantation Unit, ARNAS "Giuseppe Brotzu", Cagliari, Italy.
We report here the results of the 9th National Census (Cs-24) of Peritoneal Dialysis in Italy, carried out in 2025 by the Italian Society of Nephrology's Peritoneal Dialysis Project Group and relating to 2024. The Census was conducted in the 228 non pediatric centers which performed Peritoneal Dialysis (PD) in 2024. The results have been compared with previous Censuses carried out since 2005.
View Article and Find Full Text PDFBMJ Support Palliat Care
September 2025
Division of Nephrology, Department of Medicine, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok, Thailand
Background: End-stage kidney disease (ESKD) significantly impacts global public health, driven by an ageing population and increased chronic diseases. Over half of patients with ESKD are now over 65 years old, often with multiple comorbidities, complicating management and prognosis. The socioeconomic impact is considerable, and patients with ESKD face higher cancer risks.
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