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Maintenance of extracellular K(+) concentration within a narrow range is vital for numerous cell functions, particularly electrical excitability of heart and muscle. Potassium homeostasis during intermittent ingestion of K(+) involves rapid redistribution of K(+) into the intracellular space to minimize increases in extracellular K(+) concentration, and ultimate elimination of the K(+) load by renal excretion. Recent years have seen great progress in identifying the transporters and channels involved in renal and extrarenal K(+) homeostasis. Here we apply these advances in molecular physiology to understand how acid-base disturbances affect serum potassium.
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http://dx.doi.org/10.1681/ASN.2011040414 | DOI Listing |
Parasite Immunol
September 2025
Department of Parasitology, Leiden University Medical Center, Leiden, the Netherlands.
Schistosome parasites are known to modulate host immune responses, which is achieved in part through the release of excretory/secretory (ES) products, including extracellular vesicles (EVs). During chronic schistosomiasis, increased regulatory responses are found, which include enhanced IL-10 production by B (Breg) cells. ES products from schistosome eggs are able to induce IL-10 production by B cells.
View Article and Find Full Text PDFCurr Alzheimer Res
September 2025
Department of Biochemistry, General Medicine Practice Program, Batterjee Medical College, Jeddah, Saudi Arabia.
A serine/threonine kinase with a wide variety of substrates, Glycogen Synthase Kinase-3 (GSK-3) is widely expressed. GSK-3 is a key player in cell metabolism and signaling, modulating numerous cellular functions and playing significant roles in both healthy and diseased states. The two histopathological features of Alzheimer's disease, the intracellular neurofibrillary tangles composed of hyperphosphorylated tau, and the extracellular senile plaques composed of beta-amyloid, have been linked to GSK-3.
View Article and Find Full Text PDFWater Res
August 2025
Guangzhou Landscape Architecture Group Co., Ltd., Guangzhou 510000, PR China; Guangzhou Municipal Construction Group Co., Ltd., Guangzhou 510030, PR China.
Enhanced ammonium (10.6 - 14.7%) and total inorganic nitrogen (TIN, 4.
View Article and Find Full Text PDFJ Hazard Mater
September 2025
School of Environment and Geography, Qingdao University, Qingdao 266071, China; Carbon Neutrality and Eco-Environmental Technology Innovation Center of Qingdao, Qingdao 266071, China. Electronic address:
In this study, Fe-Ni-layered double hydroxide modified crayfish shell biochar substrate (Fe-Ni-LDH@CSBC) was successfully prepared and introduced into constructed wetland (CW) to research the Cr(VI) removal mechanism through substrate adsorption and microbial action. Adsorption experiments demonstrated the equilibrium adsorption capacities of Fe-Ni-LDH@CSBC for Cr(VI) could reach 1058.48 (C=10 mg/L) and 1394.
View Article and Find Full Text PDFAnal Chem
September 2025
Department of Analytical Chemistry, College of Chemistry, Jilin University, Changchun 130012, China.
Ginseng exosomes are a kind of promising extracellular vesicle containing unique bioactive components. However, the investigation on ginseng-derived exosomes is still in the initial stage. This study developed a photonic crystal-based Bragg scattering coupling electrochemiluminescence (BSC-ECL) biosensor for detection of miRNA396a-3p in exosome-like nanoparticles (GENs) and ginseng exosomes (Gexos).
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