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A 70-year-old man underwent a thallium-201 brain SPECT in the work-up and characterization of a frontotemporal mass. SPECT images were performed on cadmium zinc telluride system during only 5 minutes and after the injection of only 2 mCi. Images demonstrated high thallium uptake in frontotemporal areas considered as a potential malignant tumor. Surgical removal confirmed the diagnosis of malignant glioblastoma. The thallium SPECT fast acquisition imaging on cadmium zinc telluride systems is feasible with reduced injected dose. This method allows a significantly decrease of patient radiation exposure without compromising the image quality. This initial experience needs to be confirmed and optimized in larger clinical studies.
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http://dx.doi.org/10.1097/RLU.0b013e3182291efb | DOI Listing |
Comp Biochem Physiol C Toxicol Pharmacol
September 2025
Key Laboratory of Water Pollution Control and Wastewater Resource of Anhui province, Hefei, 230601, PR China; College of Environment and Energy Engineering, Anhui Jianzhu University, Hefei, 230601, PR China.
Heavy metal (HM) co-contamination is prevalent in the aquatic ecosystems and often induces complex combined effects such as synergism or antagonism, bioconcentration and biomagnification on the food-chain organisms, which is threatening the survival of living creatures and even to human health. However, the combined effects of HMs under combined exposure on the aquatic food chains still remain poorly understood. Therefore, toxic responses, bioconcentration and biomagnification of four typical HMs, lead (Pb), cadmium (Cd), nickel (Ni) and zinc (Zn), were systematically investigated under different combined exposure conditions.
View Article and Find Full Text PDFJ Trace Elem Med Biol
September 2025
Department of Neurology, Children's Hospital of Fudan University, National Children's Medical Center, Shanghai, China. Electronic address:
Objective: We previously documented that exposure to a spectrum of elements is associated with autism spectrum disorder (ASD). However, there is a lack of mechanistic understanding as to how elemental mixtures contribute to the ASD development.
Materials And Methods: Serum and urinary concentrations of 26 elements and six biomarkers of ASD-relevant pathophysiologic pathways including serum HIPK 2, serum p53 protein, urine malondialdehyde (MDA), urine 8-OHdG, serum melatonin, and urine carnitine, were measured in 21 ASD cases and 21 age-matched healthy controls of children aged 6-12 years.
Braz J Biol
September 2025
Universidade Estadual Paulista (Unesp), Instituto de Ciência e Tecnologia, Departamento de Engenharia Ambiental, São José dos Campos, SP, Brasil.
The present study carried out the first systematic review with meta-analysis on the effects of metals and temperature rise individually and their associations with terrestrial invertebrates. Initially, a systematic review of peer-reviewed articles was performed. Meta-analysis demonstrated that metals negatively affected the fitness of annelids, arthropods, and nematodes and positively affected physiological regulation in annelids.
View Article and Find Full Text PDFVet World
July 2025
Department of Geography, University College London, United Kingdom.
Background And Aim: Hospital effluents are a major source of environmental contaminants, harboring pathogenic bacteria, toxic trace metals, and high organic loads. This study aimed to evaluate the bacteriological and physicochemical profiles of wastewater discharged from three coastal hospitals in Oran, Algeria, and to assess the associated public and livestock health risks under the One Health approach.
Materials And Methods: A cross-sectional study was conducted from January 2023 to February 2024, involving monthly sampling at three hospitals and one drainage collector.
Integr Environ Assess Manag
September 2025
School of Public Health, Taipei Medical University, New Taipei City, 235040Taiwan.
Incorporating bioaccessibility into health risk assessments enhances the accuracy of exposure estimates for heavy metal (HM) pollution, supports targeted remediation, and informs public health and policy decisions, particularly for vulnerable populations. Because HM bioaccessibility depends on local soil and geographic characteristics, identifying its relationship with soil properties is crucial for assessing soil pollution potential. Although HM concentrations can be measured relatively easily, bioaccessibility requires complex laboratory procedures, limiting routine applications in regulatory contexts.
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