Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
The functional roles of miR402 in Arabidopsis thaliana were investigated under abiotic stress conditions. Overexpression of miR402 accelerated the seed germination and seedling growth of Arabidopsis under salt stress conditions, while its overexpression promoted only seed germination but not seedling growth of Arabidopsis under dehydration or cold stress conditions. The expression of DEMETER-LIKE protein3 mRNA was down-regulated in miR402-overexpressing transgenic plants. These results imply that miR402 plays a role as a positive regulator of seed germination and seedling growth of Arabidopsis under stress conditions, and that microRNA-guided regulation of DNA demethylation is an adaptive process of plants to stress conditions.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1093/pcp/pcq072 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Maladaptive role of peridroplet mitochondria during lipophagy disruption in pancreatic cancer.
Biochem Biophys Res Commun
September 2025
Laboratory of Biopharmaceutics, Graduate School of Pharmaceutical Sciences, Chiba University, 1-8-1 Inohana, Chuo-ku, Chiba-city, Chiba, 260-8675, Japan. Electronic address:
Pancreatic ductal adenocarcinoma (PDAC) cells exhibit high metabolic flexibility, enabling survival under glucose limitation by using alternative fuels such as fatty acids. Lipophagy, a selective form of autophagy targeting lipid droplets (LDs), supports mitochondrial respiration during such nutrient stress. Our previous study demonstrated that the LSD1 inhibitor SP-2509 disrupts lipophagy independently of LSD1 inhibition, leading to LD accumulation and ATP depletion in glycolysis-suppressed PDAC cells.
View Article and Find Full Text PDFIdentification of RAV transcription factors (B3-domain-containing) and functional analysis of OsRAV2 in rice blast and drought stress.
J Plant Physiol
September 2025
State Key Laboratory of Biocatalysis and Enzyme Engineering, School of Life Sciences, Hubei University, Wuhan, 430062, China. Electronic address:
RAV transcription factors play roles in a variety of diverse biological processes. However, their role in rice's response to drought and blast stress remains largely unexplored. In this study, we performed a genome-wide characterization and identification of rice RAV transcription factor family genes.
View Article and Find Full Text PDFAI modeling of Ag-ZnO milk dynamics in a squarely elevated electromagnetic tunnel with dynamic thermal modulation.
Comput Biol Chem
September 2025
Department of Mathematics, Gour Mahavidyalaya, Malda 732142, India. Electronic address:
This research proposes an advanced technique to manipulating milk flow and its thermal characteristics through a dynamic electromagnetic pathway, effectively managing the non-linear thermal behavior of milk. This study employs advanced artificial intelligence (AI) to create a sophisticated analytical framework for modeling the complex interactions between milk flow, hybrid nanoparticles (Ag-ZnO), and dynamic thermal conditions in a squarely activated electromagnetic tunnel. The research focuses on optimizing key steps in dairy manufacturing-microbial reduction and texture stabilization by analyzing the behavior of Ag-ZnO/milk under oscillating thermal amplification, incorporating radiant heat and Darcy drag effects.
View Article and Find Full Text PDFEndothelial Dysfunction and Therapeutic Advances in Chronic Kidney Disease.
Diabetes Metab Res Rev
September 2025
Department of Nephrology, Daping Hospital, Army Medical University, Chongqing, China.
Chronic kidney disease (CKD) substantially increases cardiovascular risk, with endothelial dysfunction as its central pathological mechanism. This review summarises the molecular regulatory mechanisms underlying endothelial dysfunction in CKD and highlights recent advances in treatment strategies. The pathophysiology of endothelial injuries involves a complex network of multiple factors and mechanisms, including oxidative stress, inflammation, glycocalyx damage, ischaemia, hypoxia, cellular senescence and endothelial-mesenchymal transition (EndMT).
View Article and Find Full Text PDFADSL deficiency is a secondary mitochondrial disease affecting organelle homeostasis and ERK2/AKT signaling in a linear genotype-phenotype relation.
Cell Rep
September 2025
Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy; Università Cattolica del Sacro Cuore, Rome, Italy. Electronic address:
Adenylosuccinate lyase deficiency (ADSLd) is a rare autosomal recessive purine metabolism disorder with several clinical manifestations. While toxic substrate accumulation is a known hallmark, no additional molecular mechanisms have been established. Here, we show that ADSLd is associated with mitochondrial dysfunction, including increased fragmentation, impaired respiration, and reduced ATP production.
View Article and Find Full Text PDF