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Purpose: Prospective diaries have been shown to be more reliable than retrospective questionnaires for the assessment of menstrual cycle length collected as continuous data. We investigated the reliability of retrospectively collected categorical cycle length data.
Methods: In 2005, 67 women from Illinois and Vermont completed a menstrual diary and retrospective questionnaire. Based on commonly used cutpoints for normal cycle length, we created 2-, 3- and 4-category cycle length variables, calculated percent agreement, Cohen's kappa and prevalence index and investigated factors associated with accurate reporting.
Results: Overall agreement between diary and questionnaire responses was highest for the 2-category cycle length variable, <=35 vs. > 35 days (93%), and the 3-category variable, <25, 25-35 and > 35 days (82%). While Cohen's kappa fell below 0.6, its magnitude was limited by a high prevalence of "normal"" cycle length. Women with regular cycles were slightly more likely to have concordant responses.
Conclusions: In epidemiologic studies where cycle length categories are of interest, the limitations of prospective diaries in terms of cost, compliance, attrition and power must be carefully weighed against the potentially decreased reliability of questionnaire data.
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http://dx.doi.org/10.1016/j.annepidem.2009.03.015 | DOI Listing |
Front Endocrinol (Lausanne)
September 2025
Guangxi Key Laboratory of Tumor Immunology and Microenvironmental Regulation, Guilin Medical University, Guilin, China.
Endometrial cancer (EC) is one of the most common gynecological cancers in developed countries. Like EC, most female reproductive tract malignancies are thought to be hormonally driven, with estrogen signaling acting as an oncogenic signal. The actions of estrogen are mediated through the classical nuclear estrogen receptors α (ER-α) and β (ER-β) as well as transmembrane G protein-coupled estrogen receptors (GPR30 and GPER).
View Article and Find Full Text PDFNanoscale Horiz
September 2025
Department of Chemistry and Biochemistry, University of California, Los Angeles, California 90095, USA.
Nanostructuring, which shortens lithium-ion diffusion lengths, can help facilitate pseudocapacitive behavior in some battery materials. Here, nanostructured LiNiCoAlO (NCA), with porosity and decreased crystallite size compared to commercial bulk NCA, was synthesized using a colloidal polymer template. Small particles (∼150 nm) were obtained using rapid thermal annealing (RTA), while medium particles (∼300 nm) were obtained with conventional heating.
View Article and Find Full Text PDFEMBO J
September 2025
New York University Grossman School of Medicine, Microbiology Department, New York, NY, USA.
Serine protease inhibitors (SERPINs) are involved in various physiological processes and diseases, such as inflammation, cancer metastasis, and neurodegeneration. Their role in viral infections is poorly understood, as their expression patterns during infection and the range of proteases they target have yet to be fully characterized. Here, we show widespread expression of human SERPINs in response to respiratory virus infections, both in bronchioalveolar lavages from COVID-19 patients and in polarized human airway epithelial cultures.
View Article and Find Full Text PDFLangmuir
September 2025
Department of Chemical Engineering, Indian Institute of Technology Guwahati, Guwahati, Assam 781039, India.
Simultaneous sensing and quantification of pharmaceutically active compounds (PhACs) are crucial for protecting the environment and maintaining long-term ecological sustainability. This study focuses on the bio-based synthesis of BiS-ZnO nanocomposites (BiS-ZnO(bio)) using bio-extract for dual-analyte selective and simultaneous electrochemical monitoring of phenylbutazone (PBZ) and sulfamethoxazole (SMZ) in the environmental matrices. BiS-ZnO(bio) exhibited ZnO(bio) nanostructures embedded on BiS(bio) nanorods with an average rod length of 1409.
View Article and Find Full Text PDFJ Acoust Soc Am
September 2025
Applied Physics Laboratory, University of Washington, Seattle, Washington 98105, USA.
Echolocating bats provide vital ecosystem services and can be monitored effectively using passive acoustic monitoring (PAM) techniques. Duty-cycle subsampling is widely used to collect PAM data at regular ON/OFF cycles to circumvent battery and storage capacity constraints for long-term monitoring. However, the impact of duty-cycle subsampling and potential detector errors on estimating bat activity has not been systematically investigated for bats.
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