[Urinary iodine in patients with auto-immune thyroid disorders in Santo André, SP, is comparable to normal controls and has been steady for the last 10 years].

Arq Bras Endocrinol Metabol

Disciplina de Endocrinologia, Departamento de Clínica Médica, Universidade de São Paulo, Rua Dr. Gabriel dos Santos 405, São Paulo, SP.

Published: February 2009


Category Ranking

98%

Total Visits

921

Avg Visit Duration

2 minutes

Citations

20

Article Abstract

Objective: Evaluate whether the increase of iodine in the diet would be the triggering factor for auto-immune thyropathies in the city of Santo André, SP.

Methods: Urinary iodine was determined in samples isolated from 58 patients, divided in 4 Groups, and in 13 normal individuals (controls).

Results: Urinary Iodine: Group 1--hyperthyroidism = 203.5+/-152.71 microg/ L(mean+/-sd); Group 2--hypothyroidism = 258.31+/-148,2 microg/L; Group 3--chronic auto-immune thyroiditis = 244.29+/-191.6 microg/L; Group 4--(Amiodarone) = 1157.5+/-261.8 microg/L; Group 5--Controls = 262.31+/-146.2 microg/L. On comparing the means of urinary iodine among the groups, the means for groups 1, 2, 3, and 5 did not present significant differences (p>0.05), and all differed from group 4 (p<0.05). Urinary iodine obtained in groups 1, 2, 3 and 5, obtained in 2002-03, is not different from the values determined in students in 1994 in Santo André.

Conclusion: This study shows evidence that iodine should not be considered as the responsible agent for auto-immune thyropathies in Santo André, and other environmental factors should be investigated.

Download full-text PDF

Source
http://dx.doi.org/10.1590/s0004-27302009000100009DOI Listing

Publication Analysis

Top Keywords

urinary iodine
12
microg/l group
12
santo andré
8
group
6
[urinary iodine
4
iodine patients
4
patients auto-immune
4
auto-immune thyroid
4
thyroid disorders
4
disorders santo
4

Similar Publications

The scope of this study was to characterize the iodine nutritional status of pregnant Brazilian women according to biochemical and dietary markers. It involved a cross-sectional study of 2,376 pregnant women. A semi-structured questionnaire was used to characterize the population.

View Article and Find Full Text PDF

Objective: This study aimed to reexplore minimum iodine excretion and to build a dietary iodine recommendation for Chinese adults using the obligatory iodine loss hypothesis.

Methods: Data from 171 Chinese adults (19-21 years old) were collected and analyzed based on three balance studies in Shenzhen, Yinchuan, and Changzhi. The single exponential equation was accordingly used to simulate the trajectory of 24 h urinary iodine excretion as the low iodine experimental diets offered (iodine intake: 11-26 μg/day) and to further deduce the dietary reference intakes (DRIs) for iodine, including estimated average requirement (EAR) and recommended nutrient intake (RNI).

View Article and Find Full Text PDF

The consumption of kombu plays an important role in the traditional dietary habits of East-Asian countries. However, data on the metabolic profile of kombu-derived iodine remain limited. Totally, 20 Chinese participants (age 19.

View Article and Find Full Text PDF

Introduction: Gestational age, ethnicity, assay method, thyroid autoimmunity and iodine status of the community affect thyroid hormone levels in pregnancy, and there is a need to establish trimester-specific reference ranges for thyroid hormones across different regions of the world. There was no previous study regarding this from this part of the country. The aim of this study was to establish trimester-specific reference range for thyroid hormones during pregnancy in a tertiary care centre in Southern Odisha.

View Article and Find Full Text PDF

The purpose of this study is to investigate the relationship between urinary iodine concentrations (UIC) and cognitive function among elderly individuals in certain regions of the United States, addressing a significant gap in the existing literature regarding urinary iodine and cognitive decline in older populations. UIC and cognitive function assessments of participants in the National Health and Nutrition Examination Survey were selected for the 2011-2014 cycle. Cognitive function assessments included: (1) a word learning and recall module from the Coalition to Establish a Registry for Alzheimer's Disease (CERAD); (2) an animal fluency test; and (3) the Digit Symbol Substitution Test (DSST).

View Article and Find Full Text PDF