98%
921
2 minutes
20
The mathematical model for 3D reconstruction of ocular fundus images is constructed according to both the reduced eye model and the simplified model of fundus camera optical system. The relationship between the images of emmetropic and ametropic eye and the true shape of ocular fundus retina is analyzed, and then the mapping relationship from 2D ocular fundus plan image to 3D surface image is obtained. As a result, the real example of 3D reconstruction for ocular fundus images is given. The max visual field of ocular fundus image for three-dimensional reconstruction is decided by the max visual field angle of fundus camera, which limits a size of the visual field of 3D reconstruction image and a range of z axis. According to the formulas of 3D mapping, the 2D data of ocular fundus image is mapped to 3D data and then veins mapping is carried out; thereafter, the 3D surface image of ocular fundus can be drawn immediately. This method makes use of the existing 2D imaging equipments to provide 3D surface image of patient's ocular fundus, and can provide ophthalmologist with beneficial reference and help to their clinical diagnosis and treatment.
Download full-text PDF |
Source |
---|
Int J Surg
September 2025
Department of Ophthalmology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing, China.
Objectives: To provide a bibliometric overview of the global research on the therapeutic applications of the suprachoroidal space (SCS) from 2000 to 2024.
Methods: Publications were retrieved from the Web of Science Core Collection using a defined search strategy. A total of 776 articles were analyzed for trends in publication volume, countries, institutions, authorship, journals, citations, and keywords.
Cureus
August 2025
Department of Ophthalmology, Hôpital Maisonneuve-Rosemont, Montreal, CAN.
Choroidal metastasis from occult cutaneous melanoma is rare and can masquerade as ocular inflammation. A 70‑year‑old man with sectoral anterior scleritis was found on multimodal imaging to have a solitary choroidal mass with mild periscleral fluid, prompting systemic evaluation that uncovered colonic polyps that, on histopathology, contained metastatic melanoma, a scalp primary, and widespread visceral, nodal, and intracranial metastases. Tumour cells stained HMB‑45, Melan‑A, and SOX10 positive, AE1/AE3 negative, and carried an NRAS‑Q61 mutation with wild‑type BRAF, confirming cutaneous origin.
View Article and Find Full Text PDFFront Pediatr
August 2025
Department of Ophthalmology, Peking University People's Hospital, Beijing, China.
Background: The m.3243A>G mutation in the MT-TL1 gene is the most common mtDNA mutation. The mutation can lead to a spectrum of conditions, including diabetes, hearing loss, heart and muscle involvement, encephalopathy and epilepsy, gastrointestinal problems, and vision impairment, often occurring concurrently-collectively referred to as MELAS (mitochondrial encephalopathy lactic acidosis and stroke-like episodes) syndrome.
View Article and Find Full Text PDFPhotodiagnosis Photodyn Ther
September 2025
State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science, Guangdong Provincial Clinical Research Center for Ocular Diseases, Guangzhou, China. Electronic address:
Purpose: To characterize the cavity hyperreflective-content and septum's motion artifact (CHASMA) in en face optical coherence tomography angiography (OCTA) across multiple ocular fundus abnormalities.
Methods: This was a cross-sectional, observational study. Subjects with extravascular OCTA signals arising from the cavity's hyperreflective-content and/or septum were enrolled.
Int Ophthalmol
September 2025
Beijing Tongren Eye Center, Beijing Tongren Hospital, Beijing key Laboratory of Intraocular Tumor Diagnosis and Treatment, Beijing Ophthalmology and Visual Sciences Key Lab, Medical Artificial Intelligence Research and Verification Key Laboratory of the Ministry of Industry and Information Technolog
Purpose: To analyze macular microvascular networks and investigate correlations between visual acuity and quantitative parameters in patients with Leber's hereditary optic neuropathy (LHON) using optical coherence tomography angiography (OCTA).
Methods: An observational, cross-sectional study was conducted, including 25 eyes from 25 genetically confirmed chronic LHON patients and 25 eyes from 25 age-matched healthy controls. Images were obtained using a spectral domain OCTA system.