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Geochemical study of groundwater from a structurally deformed granitic terrain near Hyderabad (India) was carried out to understand and evaluate the hydrogeochemical processes and quality of groundwater. Several trace elements (Fe, Mn, Be, Al, V, Cr, Co, Ni, Cu, Zn, As, Sr, Mo, Cd, Sb, Ba, Pb, U) along with major ions and minor elements were precisely estimated in shallow and drilled wells to know the suitability of water for drinking and irrigation purposes. Analytical data shows that pH and major ion chemistry in dug wells and bore wells do not vary significantly, while some trace elements (Fe, Mn, Al, Be, Co, Pb, U and Zn) vary in dug wells and bore wells, which can be attributed to differential mineral weathering and dissolution/precipitation reactions along fractures/joints. Although the water is not potable, it was found to be suitable for irrigation with little danger in the development of harmful level of exchangeable sodium. It is inferred that the chemical composition of the groundwater in this region is likely to have its origin from silicate weathering reactions and dissolution/precipitation processes supported by rainfall and groundwater flow.
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http://dx.doi.org/10.1007/s10661-006-9461-9 | DOI Listing |
Brain Behav
September 2025
The National Clinical Research Center for Mental Disorders & Beijing Key Laboratory of Mental Disorders, Beijing Anding Hospital, Capital Medical University, Beijing, China.
Background: Diverse correlations between structural brain abnormalities and the clinical feature of bulimia nervosa (BN) have been identified in previous observational studies.
Objective: To explore the bidirectional causality between BN and brain structural magnetic resonance imaging (MRI) phenotypes.
Methods: Genome-wide association studies (GWAS) of 2441 participants identified genetic variants associated with disordered eating and predicted BN, whereas UK Biobank 3D-T1 MRI data were used to analyze brain structural phenotypes.
Nature
September 2025
Picower Institute for Learning and Memory, Massachusetts Institute of Technology, Cambridge, MA, USA.
Loss-of-function variants in the lipid transporter ABCA7 substantially increase the risk of Alzheimer's disease, yet how they impact cellular states to drive disease remains unclear. Here, using single-nucleus RNA-sequencing analysis of human brain samples, we identified widespread gene expression changes across multiple neural cell types associated with rare ABCA7 loss-of-function variants. Excitatory neurons, which expressed the highest levels of ABCA7, showed disrupted lipid metabolism, mitochondrial function, DNA repair and synaptic signalling pathways.
View Article and Find Full Text PDFSemin Ultrasound CT MR
September 2025
Department of Radiology, University of North Carolina at Chapel Hill, Chapel Hill, NC. Electronic address:
Fetal magnetic resonance imaging (MRI) is a safe method of in-utero evaluation of fetal anomalies and a valuable adjunct to prenatal ultrasound. The utilization of rapid sequences reduces the impact of fetal motion and allows for high contrast resolution of fetal structures. A thorough understanding of fetal anatomy and a systematic approach to MRI interpretation are essential for accurate diagnosis of fetal head and neck anomalies.
View Article and Find Full Text PDFBiomed Phys Eng Express
September 2025
Southwest Jiaotong University School of Mechanical Engineering, No. 111, North Section 1, Second Ring Road, Jinniu District, Chengdu, Chengdu, Sichuan, 610031, CHINA.
Total hip arthroplasty (THA) is the standard surgical treatment for end-stage hip osteoarthritis, with its success dependent on precise preoperative planning, which, in turn, relies on accurate three-dimensional segmentation and reconstruction of the periarticular bone of the hip joint. However, patients with hip osteoarthritis often exhibit pathological characteristics, such as joint space narrowing, femoroacetabular impingement, osteophyte formation, and joint deformity. These changes present significant challenges for traditional manual or semi-automatic segmentation methods.
View Article and Find Full Text PDFSoft Robot
September 2025
The School of Electrical and Mechanical Engineering, The University of Adelaide, Adelaide, Australia.
Soft robotic systems are promising for diverse space applications due to their embedded compliance, promising locomotion methods, and efficient use of mass and volume. Space environments are harsher and more varied than those on Earth; extreme temperature, pressure, and radiation may impact the performance and robustness of soft robots. Cryogenic temperatures on celestial bodies such as the Moon or Europa pose significant challenges to the flexibility and actuation performance of conventional soft systems.
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