Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
Purpose: Surgical treatment of hemodynamically significant carotid artery stenoses has been well documented, especially in the asymptomatic patient. However, in those patients presenting with hemodynamically significant asymptomatic carotid artery disease who are to undergo cardiac surgery, optimal treatment remains controversial. In this study, we analyze our experience with patients who underwent synchronous carotid endarterectomy (CEA) and coronary artery bypass graft procedures (CABG) for hemodynamically significant (>70%) asymptomatic carotid artery stenosis and coronary artery disease (CAD).
Methods: Demographics and outcomes of all patients undergoing synchronous CEA/CABG for asymptomatic carotid stenosis between April 1980 and January 2005 were reviewed from our vascular registry and patient charts. We included patients who underwent standard patching of their carotid artery and those undergoing eversion CEA. All neurologic events within the first 30 days that persisted >24 hours were considered a stroke. For purposes of comparison, we also reviewed outcomes for patients undergoing synchronous CEA/CABG for symptomatic carotid stenosis.
Results: Asymptomatic carotid artery stenosis (>70%) was the indication in 702 patients (276 women and 426 men) undergoing 758 CEAs. In the asymptomatic group, 22 patients, of which 21 succumbed to cardiac dysfunction, and one died from a hemorrhagic stroke. The overall mortality rate was 3.1%. Seven permanent nonfatal neurologic deficits occurred in this series (1 woman, 6 men). The combined stroke mortality was 4.3%. This compares to a 30-day stroke mortality of 6.1% in 132 symptomatic combined CEA/CABG patients. The difference in stroke mortality in women compared with men was not significant.
Conclusion: In this experience, patients presenting with hemodynamically significant (>70%) asymptomatic carotid artery stenosis can undergo synchronous CEA/CABG with low morbidity and mortality.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.jvs.2006.03.031 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Association between remnant cholesterol and atherosclerosis plaques in single and multiple vascular territories.
Zhong Nan Da Xue Xue Bao Yi Xue Ban
May 2025
Department of Hepatobiliary and Pancreatic Surgery, Third Xiangya Hospital, Central South University, Changsha 410013, China.
Objectives: In recent years, the role of remnant cholesterol (RC) in the development and progression of cardiovascular diseases has gained increasing attention. However, evidence on the association between RC and subclinical atherosclerosis is limited. This study aims to examine the relationship between RC and atherosclerotic plaques in single and multiple vascular territories.
View Article and Find Full Text PDFStereotactic Step-by-step Dissection of the Anterior Transpetrosal Approach: A Three-dimensional Photogrammetry-based Educational Tool for Neurosurgeons.
Neurol Med Chir (Tokyo)
September 2025
Department of Neurosurgery, Keio University School of Medicine.
Skull base surgery requires precise spatial recognition; however, existing educational tools remain limited. To address this issue, we developed a step-by-step stereotactic three-dimensional anatomical model of the anterior transpetrosal approach using digital photogrammetry. Cadaveric dissection was subsequently performed in 17 steps, of which 10 were reconstructed into three-dimensional models.
View Article and Find Full Text PDFMachine Learning Models for Carotid Artery plaque Detection: A Systematic Review of Ultrasound-Based Diagnostic Performance.
J Stroke Cerebrovasc Dis
September 2025
College of Human Medicine, Michigan State University, East Lansing, Michigan, USA.. Electronic address:
Background: Carotid artery plaques, a hallmark of atherosclerosis, are key risk indicators for ischemic stroke, a major global health burden with 101 million cases and 6.65 million deaths in 2019. Early ultrasound detection is vital but hindered by manual analysis limitations.
View Article and Find Full Text PDFYXQN Ameliorates Vascular Dementia in 2-VO Rats via Inhibition of Ferroptosis.
J Ethnopharmacol
September 2025
Department of Integration of Chinese and Western Medicine, School of Basic Medical Sciences, Peking University, Beijing, China; Academy of Integration of Chinese and Western Medicine, Peking University Health Science Center, Beijing, China; The Key Discipline for Integration of Chinese and Western B
Ethnopharmacological Relevance: YangXue QingNao Wan (YXQN) is a compound Chinese medicine comprising of 11 traditional Chinese medicinal herbs, including Angelica sinensis, Ligusticum chuanxiong, and Paeonia lactiflora, etc. Previous studies in our laboratory have demonstrated that YXQN improved cerebral microcirculation in hypertensive rats. However, its efficacy and underlying mechanisms in treating vascular dementia (VaD) remain unclear.
View Article and Find Full Text PDFImpact of carotid web orientation on long-term thrombus growth risk: A numerical study using fluid-solid interaction.
Comput Methods Programs Biomed
August 2025
School of Computer Science and Technology, Southwest University of Science and Technology, Mianyang 621010, China. Electronic address:
Background: Carotid web (CaW) is a rare fibromuscular dysplasia lesion at the carotid bifurcation linked to thromboembolic events in young patients. CaW-induced hemodynamic disturbances contribute to thrombosis, but the impact of CaW morphology on long-term thrombotic risk remains unclear.
Method: This study developed three-dimensional numerical models based on patient-specific carotid artery anatomy with CaW angles of 30°, 60°, and 90° (models A, B, and C).