Nanoarchitectonics on Oxygen-Rich Vacancy C/OVs-Ni-Cu-LDHs@MnO Tubular Micromotors for Sensitive Detection and Efficient Catalytic Degradation.

C/OVs-Ni-Cu-LDHs@MnO tubular micromotors with enzyme-like activity and abundant oxygen vacancies (OVs) were synthesized hydrothermally using kapok as a biotemplate. MnO acted as the micromotor's "driving engine", catalyzing the generation of HO bubbles to provide driving force for the motor, enabling efficient motion (144.45 ± 3.

Hybrid-Fueled OV-CuFe-CNT/MnO/GOx Micromotor for Colorimetric Detection and Degradation of Captopril via Free Radical and Nonradical Mediated by Oxygen Vacancy.

Addressing the challenges of metal particle corrosion and active site loss induced by excessive use of high-concentration hydrogen peroxide (HO) is essential to expand micro/nanomotor (MNM) applications in biological and environmental fields. Herein, a novel hybrid fuel-driven CuFe-CNT/MnO/GOx (GOx, glucose oxidase) micromotor with abundant oxygen vacancy (OV) was successfully constructed for synchronous high-efficiency colorimetric detection and rapid degradation of captopril (CP). Using glucose and low-concentration HO as hybrid fuels, the OV-CuFe-CNT/MnO/GOx micromotor could move at a speed of 107.

Sodium percarbonate fuel-driven magnetic micromotor for rapid detection and efficient removal of tetracycline: Synergistic effect of oxygen vacancy and dissolved oxygen.

Micro/nanomotors (MNMs) propelled by hydrogen peroxide (HO) fuel have garnered significant interest in sensitive colorimetric detection and rapid catalytic degradation of organic pollutants. However, their practical applications remain constrained by multiple limitations including toxic high-concentration HO requirements, sluggish Fe/Fe redox cycling, and secondary contamination risks from metal ion leaching. Herein, we rationally developed a novel magnetic tubular FeCu@NC/MnO micromotor through multistep fabrication using kapok-derived C microtubes as templates.

Zirconium Metal-Organic Frameworks as Micromotors with Enzyme-like Activity for Glutathione Detection.

Herein, we report a novel UiO-67-Co(bpy) micromotor synthesized by a facile postsynthesis metalation via introducing cobalt salts ligated with 2,2'-bipyridine-5,5'dicarboxylic acid into UiO-67-bpy framework. The Co active sites can decompose HO to generate bubbles to power UiO-67-Co(bpy). Meanwhile, the UiO-67-Co(bpy) micromotor exhibits robust peroxidase-like activity through catalyzing HO to generate OH under neutral conditions.

Association between weekend catch-up sleep and depression in US adults.

Background: Depression is one of the most prevalent mental disorders and causes a serious economic and medical burden on society. This research assessed the correlation between weekend catch-up sleep (WCS) and depression in US adults aged ≥ 20 years.

Methods: Cross-sectional data were obtained from individuals with complete WCS and Patient Health Questionnaire (PHQ-9) data who participated in the 2017-2020 National Health and Nutrition Examination Survey (NHANES).

Role and mechanisms of mast cells in brain disorders.

Mast cells serve as crucial effector cells within the innate immune system and are predominantly localized in the skin, airways, gastrointestinal tract, urinary and reproductive tracts, as well as in the brain. Under physiological conditions, brain-resident mast cells secrete a diverse array of neuro-regulatory mediators to actively participate in neuroprotection. Meanwhile, as the primary source of molecules causing brain inflammation, mast cells also function as the "first responders" in brain injury.

TGF-β1 mediates hypoxia-preconditioned olfactory mucosa mesenchymal stem cells improved neural functional recovery in Parkinson's disease models and patients.

Background: Parkinson's disease (PD) is a neurodegenerative disorder characterized by the degeneration of dopaminergic neurons in the substantia nigra (SN). Activation of the neuroinflammatory response has a pivotal role in PD. Mesenchymal stem cells (MSCs) have emerged as a promising therapeutic approach for various nerve injuries, but there are limited reports on their use in PD and the underlying mechanisms remain unclear.

Positive association of ethylene oxide levels with young stroke: a population-based study.

Background: Ethylene oxide (EtO), a highly reactive organic compound with extensive industrial applications, poses significant health risks. The association between EtO exposure and stroke was not well established. This study examined the association between EtO exposure and stroke among US adults using data from the 2013-2018 National Health and Nutrition Examination Survey (NHANES).

Curcumin-primed olfactory mucosa-derived mesenchymal stem cells mitigate cerebral ischemia/reperfusion injury-induced neuronal PANoptosis by modulating microglial polarization.

Background: Cerebral ischemia-reperfusion (I/R) injury often leads to neuronal death through persistent neuroinflammatory responses. Recent research has unveiled a unique inflammatory programmed cell death mode known as PANoptosis. However, direct evidence for PANoptosis in ischemic stroke-induced neuronal death has not been established.

Mesenchymal stem cell-derived exosomes overexpressing SRC-3 protect mice from cerebral ischemia by inhibiting ferroptosis.

Background: The treatment for cerebral ischemia remains limited, and new therapeutic strategies are urgently needed. Exosome has shown great promise for the treatment of cerebral ischemia. Steroid receptor coactivator-3 (SRC-3) was reported to be involved in neurological performances.

The role of short-chain fatty acids in central nervous system diseases: A bibliometric and visualized analysis with future directions.

Background: Short-chain fatty acids (SCFAs) are thought to play a key role in the microbe-gut-brain axis and involve in the pathogenesis of a variety of neurological diseases. This study aimed to identify research hotspots and evolution trends in SCFAs in central nervous diseases (CNS) and examine current research trends.

Methods: The bibliometric analysis was performed using CiteSpace, and the results were visualized via network maps.

Dual source-powered multifunctional Pt/FePc@Mn-MOF spindle-like Janus nanomotors for active CT imaging-guided synergistic photothermal/chemodynamic therapy.

Nanomaterials capable of dual therapeutic effects of chemodynamic therapy (CDT) and photothermal therapy (PTT) is an efficacious strategy in cancer treatment. It is still a challenge to achieve complete apoptosis of tumor tissue in CDT/PTT due to the poor permeability of nanomaterials in tumor tissue. Herein, we prepared a dual-source driven Pt/FePc@Mn-MOF spindle-like Janus nanomotor by a facile oriented connection growth method for computed tomography (CT) imaging-guided CDT and PTT.

Corrigendum to "The 100 top-cited articles in the field of Wilson's disease from 1990 to 2022: A bibliometric study" [Heliyon 9(7) (July 2023) e17785].

[This corrects the article DOI: 10.1016/j.heliyon.

Hierarchical hollow α-FeO/ZnFeO/MnO Janus micromotors as dynamic and efficient microcleaners for enhanced photo-Fenton elimination of organic pollutants.

Micro/nanomotors that can promote mass transport have attracted more and more research concern in the photocatalysis field. Here we first report a newly-designed hierarchical α-FeO/ZnFeO/MnO magnetic micromotor as a heterogeneous photocatalyst for the degradation of cationic dye methylene blue (MB) from wastewater. The resulting three-dimensional (3D) flower-like hollow Janus micromotors are fabricated through a green and scalable strategy, in which each component has different functions.

The 100 top-cited articles in the field of Wilson's disease from 1990 to 2022: A bibliometric study.

Objectives: To characterize the 100 most-cited articles in the field of Wilson's Disease (WD) to provide a general overview and reveal the historical developments classical studies, and new findings.

Design: WD-related articles were searched on the Web of Science database. The 100 most-cited articles were retrieved and their descriptive statistics were analyzed.

Bone marrow-derived mesenchymal stem cells overexpressed with miR-182-5p protects against brain injury in a mouse model of cerebral ischemia.

Background: Toll-like receptor 4 (TLR4) plays a critical role in ischemic brain injury by mediating the inflammatory response. The microRNA miR-185-5p suppresses inflammatory signaling by targeting TLR4. This study investigates whether overexpressing miR-182-5p in bone marrow-derived mesenchymal stem cells (BM-MSCs) could potentiate the neuroprotective effects of BM-MSCs in a mouse model of ischemic brain injury.

Insights into the dewatering of excavated landfill sludge conditioned by polyferric silicate sulfate.

Large quantities of landfill sludge (LS) with higher water content (WC) were stored underground, and excavation and re-dewatering of LS is a sustainable and economic strategy to save landfill space and reduce the leaching of contaminants. In this study, polyferric silicate sulfate (PFSS) was first applied in the conditioning of excavated LS, and the effects of the Si/Fe mass ratio and PFSS dosage on physicochemical properties, dewaterability and rheological properties were investigated. At the best Si/Fe of 0.

A novel and low-cost CuPc@C catalyst derived from the compounds of sunflower straw and copper phthalocyanine pigment for oxygen reduction reaction.

A series of carbon and phthalocyanine catalysts were prepared with uniform and stretchable sunflower straw biological materials as the carbon source and inexpensive copper phthalocyanine (CuPc) pigment as a nitrogen doping source by a facile high-temperature carbonization method. This kind of biomass carbon material sunflower straw with abundant pore structure and sponge-like expansion and contraction functions can not only be used as a source of porous carbon in biomass carbon materials, but also as a carbon carrier with high specific surface area to provide nanoparticle adhesion sites. When it was immersed in the copper phthalocyanine pigment solution, more active sites could be exposed, so that CuPc particles could be uniformly doped and distributed on the porous carbon material.

Mesenchymal stem cells-derived therapies for subarachnoid hemorrhage in preclinical rodent models: a meta-analysis.

Background: Mesenchymal stem cells (MSCs) and MSCs-derived extracellular vesicles (EVs) have emerged as potential novel therapies for subarachnoid hemorrhage (SAH). However, their effects remain incompletely understood. We aim to comprehensively evaluate the effect of MSCs-derived therapies in rodent models of SAH.

High-Level Oxygen Reduction Catalysts Derived from the Compounds of High-Specific-Surface-Area Pine Peel Activated Carbon and Phthalocyanine Cobalt.

Non-platinum carbon-based catalysts have attracted much more attention in recent years because of their low cost and outstanding performance, and are regarded as one of the most promising alternatives to precious metal catalysts. Activated carbon (AC), which has a large specific surface area (SSA), can be used as a carrier or carbon source at the same time. In this work, stable pine peel bio-based materials were used to prepare large-surface-area activated carbon and then compound with cobalt phthalocyanine (CoPc) to obtain a high-performance cobalt/nitrogen/carbon (Co-N-C) catalyst.

SRC3 Promotes the Protective Effects of Bone Marrow Mesenchymal Stem Cell Transplantation on Cerebral Ischemia in a Mouse Model.

Mesenchymal stem cells (MSCs) derived from the bone marrow (BM) are reported to protect against ischemic brain injury. This study aimed to investigate whether the steroid receptor cofactor 3 (SRC3) was involved in MSC-induced neuroprotection. BM-MSCs were isolated from wild-type (WT) and SRC3 knockout (SRC3) mice and transplanted into mice with middle cerebral artery occlusion (MCAO).

The Efficacy of Mesenchymal Stem Cell Therapies in Rodent Models of Multiple Sclerosis: An Updated Systematic Review and Meta-Analysis.

Studies have demonstrated the potential of mesenchymal stem cell (MSC) administration to promote functional recovery in preclinical studies of multiple sclerosis (MS), yet the effects of MSCs on remyelination are poorly understood. We wished to evaluate the therapeutic effects of MSCs on functional and histopathological outcomes in MS; therefore, we undertook an updated systematic review and meta-analysis of preclinical data on MSC therapy for MS. We searched mainstream databases from inception to July 15, 2021.

17β-Estradiol Attenuates Intracerebral Hemorrhage-Induced Blood-Brain Barrier Injury and Oxidative Stress Through SRC3-Mediated PI3K/Akt Signaling Pathway in a Mouse Model.

Estrogen is neuroprotective in brain injury models, and steroid receptor cofactor 3 (SRC3) mediates estrogen signaling. We aimed to investigate whether and how SRC3 is involved in the neuroprotective effects of 17ß-estradiol (E2) in a mouse model of intracerebral hemorrhage (ICH). Ovariectomized female mice were treated with E2 after autologous blood injection-induced ICH.

SRC-3 Deficiency Exacerbates Neurological Deficits in a Mouse Model of Intracerebral Hemorrhage: Role of Oxidative Stress.

Intracerebral hemorrhage (ICH) causes long term neurological abnormality or death. Oxidative stress is closely involved in ICH mediated brain damage. Steroid receptor cofactor 3 (SRC-3), a p160 family member, is widely expressed in the brain and regulates transactivation of Nrf2, a key component of antioxidant response.

Case Report and Literature Analysis: Guillain-Barré Syndrome With Delayed Unilateral Facial Palsy.

Guillain-Barré syndrome (GBS) is an acute inflammatory polyradiculoneuropathy in which most patients have cranial nerve involvement, with facial nerve involvement being the most common. However, delayed facial palsy (DFP) with asymmetric facial palsy is a rare manifestation of GBS, and the mechanism is unclear. We report a case of GBS combined with delayed unilateral facial palsy and review previously reported cases of GBS combined with DFP.