The efficacy of metastasis-directed external beam radiotherapy for castration-resistant prostate cancer: A retrospective multicenter study.

Background: To assess the efficacy of metastasis-directed external beam radiotherapy (MDT) in patients with castration-resistant prostate cancer (CRPC), we conducted a multicenter retrospective study.

Materials And Methods: We retrospectively analyzed data from patients with metastatic CRPC treated with MDT between January 2013 and July 2023 across 14 hospitals. Patients who received palliative or local radiation therapy or had insufficient clinical data were excluded.

Treatment-Induced Gene Expression Changes in Metastatic Renal Cell Carcinoma: Insights from a Syngeneic Mouse Model.

This study aimed to clarify the alterations in gene expression in metastatic renal cell carcinoma (mRCC) during disease progression and in response to treatment with immune checkpoint inhibitors using a syngeneic mouse mRCC model. RENCA cells were orthotopically implanted in BALB/c mice. Mice received first-line treatment with cabozantinib, anti-PD-1 antibody, or a combination.

Is There a Role for Music Intervention in Reducing Anxiety and Pain in Males During Outpatient Flexible Cystoscopy? A Randomized Controlled Study.

Objective: To prospectively verify whether music intervention reduces the anxiety and pain in male patients undergoing outpatient flexible cystoscopy in a randomized control trial. Methods: A total of 100 male patients undergoing outpatient flexible cystoscopy from May to November 2023 were randomly assigned to the music intervention group or control group. Spielberger's State-Trait Anxiety Inventory (STAI) was used to assess the anxiety.

Prevalence of Discordance Between Patient- and Physician-Reported Questionnaire in Japanese Male: Insight From a Prospective Observational Study Using the International Prostate Symptom Score.

Objectives: This study aimed to prospectively clarify the prevalence of discordance between patient- and physician-reported International Prostate Symptom Score in Japanese males and evaluate the factors affecting the discordant response of the questionnaire.

Methods: From May 2022 to December 2023, a prospective single-institutional observational study was conducted. A total of 310 male patients with lower urinary tract symptoms were prospectively registered to the study.

Clinical Outcomes of Untreated Recurrence After Radical Surgery for Upper Urinary Tract Carcinoma: A Multicenter Retrospective Study.

Objectives: To investigate the prognoses of patients with upper urinary tract carcinoma who had recurrence after radical nephroureterectomy according to the presence or absence of systemic therapy after recurrences. Moreover, to evaluate the reasons for not being treated and to predict these untreated patients using pre-surgical clinical factors.

Methods: We retrospectively evaluated patients who underwent radical nephroureterectomy between 2012 and 2022.

Water Vapor Energy Therapy Safely Reduces Urinary Medication Use: A Multicenter Retrospective Real-World Study in Japan (SCCOP Study 24-01).

Objective: The Japanese guidelines for male lower urinary tract symptoms (LUTS) and benign prostatic hyperplasia (BPH) recommend the water vapor energy therapy (WAVE) procedure only for patients in whom conventional BPH surgery is unsuitable due to advanced age or comorbidities. This study aims to evaluate the efficacy and safety of the WAVE procedure using the Rezum system in Japan.

Methods: This multicenter retrospective study included patients who underwent the WAVE procedure between August 2022 and December 2023.

Voiding With Less Strength of Desire to Void Is a Risk Factor for Post Micturition Dribble.

Objective: To clarify what urinary condition causes post micturition dribble (PMD) in non-elderly healthy men. We focused on men with PMD who do not have PMD every time they void. We clarified what urinary condition was associated with PMD in individuals to prevent PMD.

Differential Risk Factors for Early Intravesical Recurrence After Radical Nephroureterectomy for Upper Urinary Tract Carcinoma According to the History of Non-Muscle Invasive Bladder Cancer.

Objectives: To evaluate the preoperative risk factors for early intravesical recurrence after radical nephroureterectomy (RNU) in patients with upper urinary tract carcinoma (UTUC) according to the history of non-muscle invasive bladder cancer (NMIBC).

Methods: We retrospectively evaluated patients who underwent RNU for UTUC between 2012 and 2022 at 14 hospitals. Early recurrence was defined as intravesical pathologically confirmed recurrence within 1 year after RNU.

The Change of Detrusor Contractility at 5 Years After Transurethral Resection of the Prostate: A Single Center Prospective Observational Study.

Objective: To prospectively assess the impact of transurethral resection of the prostate (TURP) on detrusor function using pressure flow study (PFS) at 5 years after surgery in a single center prospective non-randomized observational study.

Methods: Sixty consecutive male patients were prospectively enrolled and underwent TURP from November 2014 to November 2018. A questionnaire survey, free uroflowmetry, and PFS were performed at baseline, and 6, 24, and 60 months after surgery.

Successful retroperitoneal laparoscopic nephroureterectomy for thoracic kidney in a patient with ipsilateral ureteral cancer.

A thoracic kidney is a scarce type of ectopic kidney. We report the case of a 76-year-old man who developed cancer of the ureter, ipsilateral to the thoracic kidney. He presented with abdominal pain in the right upper quadrant.

Which characteristics are associated with changes in medication status for lower urinary tract symptoms among patients with prostate cancer receiving external beam radiotherapy?

Background: We clarified the predictive factors for changes in the status of medications for lower urinary tract symptoms (LUTS) 2 years after local radiotherapy for nonmetastatic prostate cancer.

Materials And Methods: We retrospectively included patients who underwent local external radiotherapy for nonmetastatic prostate cancer in 8 institutions between April 2001 and March 2016. Patients were divided into the medication and no-medication group based on the use of drugs for LUTS before radiotherapy.

Intrinsic and extrinsic factors causing hyperplasia of the prostate.

Prostatic hyperplasia is very common in elderly men and is a typical disease that reduces quality of life. Histologically, hyperplasia of the prostate gland causes obstruction at the bladder outlet, resulting in symptoms such as a weak urine stream. Various factors have been considered to cause histological enlargement of the prostate, but the underlying cause is still unknown.

[A Case of Neuropathic Lower Urinary Tract Dysfunction Due to Spina Bifida Occulta Discovered at the Age of 19 Years and Successfully Treated with Multidisciplinary Therapy].

A 19-year-old man had been aware of dysuria and urinary incontinence since childhood but did not seek medical attention. He was diagnosed with acute pyelonephritis due to lower urinary tract dysfunction associated with spina bifida occulta and tethered cord syndrome (TCS) due to spinal cord lipoma. After placement of a urethral catheter and antibacterial chemotherapy, the patient was cured of acute pyelonephritis.

[Two Cases of Retroperitoneal Synovial Sarcoma].

We experienced two cases of renal primary synovial sarcoma. Case 1: A 29-year-old man underwent laparoscopic radical nephrectomy and was originally diagnosed with renal cell carcinoma. Case 2: A 25-year-old man was treated by open radical nephrectomy since radiographical findings indicated tumor invasion to the ureter causing hydronephrosis.

Development and preliminary evaluation of a novel procedure for creation of an ileal conduit stoma aimed at preventing parastomal hernia.

Objectives: Our previous study suggested that the operative procedure is critical for the development of parastomal hernia. We developed a novel procedure for the creation of an ileal conduit stoma to prevent parastomal hernia. Herein we evaluate the efficacy and safety of the procedure.

Systemic sarcoidosis presenting as a rare combination of interstitial nephritis with necrotizing vasculitis and urinary retention due to prostate involvement: a case report.

Background: Sarcoidosis affects multiple organs and exhibits diverse clinical manifestations. Although tubulointerstitial nephritis is a known feature of renal involvement, necrotizing vasculitis is rare. Furthermore, prostate involvement with urinary retention is unusual in patients with sarcoidosis.

Efficacy of cognitive behavioral therapy using self-check sheet for patients with nocturia in real-world clinical practice.

Objectives: We previously demonstrated the efficacy of cognitive behavioral therapy (CBT) using a self-check sheet for patients with nocturia in a randomized controlled study. Additionally, we investigated the efficacy of the intervention in real-world clinical practice.

Methods: Two hundred forty-three outpatients with complaint of nocturia who practiced CBT for 4 weeks using a self-check sheet were included in this trial, which took place from April 2021 to March 2022 in 20 institutions.

Difference in symptom manifestation between postmenopausal and premenopausal women in acute uncomplicated cystitis: A multi-institutional pilot study.

Objectives: We aimed to prospectively compare lower urinary tract symptoms in premenopausal and postmenopausal women with acute uncomplicated cystitis before and after antibiotic therapy.

Materials And Methods: This study included adult women with acute uncomplicated cystitis who visited 4 institutions between 2019 and 2020. After registration, we administered oral antibiotics and prospectively documented the changes in lower urinary tract symptoms from the first visit to a follow-up visit at 1 week using the Core Lower Urinary Tract Symptoms Score (CLSS) questionnaire.

[A RETROSPECTIVE ANALYSIS OF SURGICAL POSITIONING INJURY USING INCIDENT REPORTING SYSTEM].

(Purpose) Surgical positioning injury (SPI) is a cutaneous, musculoskeletal, neurological, or vascular injury resulting from the position of the patient during surgery. We performed a retrospective study using incident reporting system to examine the incidence of SPI at our hospital. (Materials and methods) Among anesthesiology managed surgical cases, SPI cases reported in the incident reporting system between 2012 and 2017 were examined.

Clinical characteristics and treatment outcomes of patients with small cell carcinoma of the urinary bladder.

Background: Small cell carcinoma of the urinary bladder (SCUB) is rare. The optimal treatment for SCUB remains unclear. To address the problem of appropriate treatment for each case, we assessed single-modality and surgery-based multimodality treatments in patients with SCUB.