Publications by authors named "Yu-Lin Ding"

is the most widely distributed tick genus in China. , a predominant tick species in Inner Mongolia, can carry and transmit pathogenic microorganisms. Here, were collected from Ordos (O-D) and Hinggan League (H-D) in the Inner Mongolia.

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Background: Paratuberculosis (PTB), caused by Mycobacterium avium subsp. paratuberculosis (MAP), is difficult to diagnose in the early stages and poses substantial challenges in prevention, control, treatment, and eradication. A well-defined animal model can help identify disease markers and serve as a platform for vaccine and drug development.

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Background: Paratuberculosis (PTB) is a chronic wasting disease mainly caused by subsp. (MAP) in ruminants. It is difficult to diagnose, prevent, treat, and eradicate, thereby causing serious economic losses to the livestock industry.

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Enterocytozoon bieneusi is a zoonotic pathogen, with cattle serving as major reservoirs and important mediums for its transmission. However, data on the prevalence and subtypes of E. bieneusi in cattle from Northern Shanxi and Central Inner Mongolia, China, are limited.

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Paratuberculosis (PTB), primarily caused by subsp. (MAP), is a chronic infection that affects ruminants and is difficult to prevent, diagnose, and treat. Investigating how MAP infections affect the gut microbiota in sheep can aid in the prevention and treatment of ovine PTB.

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Article Synopsis
  • Three common intestinal protozoan pathogens—Cryptosporidium spp., Enterocytozoon bieneusi, and Giardia duodenalis—were studied in fecal samples from 320 dairy cattle in Ningxia to assess their prevalence and genetic profiles.
  • Results showed a significant infection rate: 61.56% of samples were positive for at least one pathogen, with E. bieneusi being the most prevalent (41.56%), followed by G. duodenalis (29.38%) and Cryptosporidium (19.38%).
  • The study identified multiple species and genotypes of these pathogens, including mixed infections and notable dominance of specific genotypes, highlighting the zoonotic potential and need for better understanding in
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  • The study focused on the prevalence and genetic diversity of the Giardia duodenalis protozoan in dairy cattle in Central Inner Mongolia, highlighting the potential risk of giardiasis transmission to humans, particularly from cattle.
  • Researchers analyzed 505 fecal samples from dairy cows, revealing a G. duodenalis prevalence of 29.5%, with higher rates in diarrheal samples, though results were statistically insignificant.
  • The majority of detected parasites belonged to assemblage E, with findings indicating a diverse range of multilocus genotypes, marking this as the first report of G. duodenalis infection in dairy cattle in this region.
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  • Cryptosporidium is a protozoan pathogen found in cattle, leading to human gastrointestinal illness; this study examines its prevalence in dairy cattle in Central Inner Mongolia.
  • Out of 505 manure samples, 29.90% tested positive for Cryptosporidium, with the highest rates in diarrheal samples (37.67%), and four species were identified, mainly C. bovis and C. andersoni.
  • The study provides new insights on Cryptosporidium distribution in dairy cattle, marking a significant contribution to understanding its impact on public health and zoonotic transmission.
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Ticks were identified as arthropods that are pathogenic vectors. is one of the dominant tick species in Inner Mongolia, and it carries and transmits a wide range of pathogenic microorganisms. However, at present, only the detection of adult ticks and different developmental stages carrying one specific pathogen, or the next-generation sequencing of adult ticks were available.

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  • Sheep keds are common ectoparasites in sheep that cause harm by biting, sucking blood, and potentially spreading various pathogens like helminths and bacteria.
  • In a study conducted in Tibet, DNA was extracted from sheep samples, followed by next-generation sequencing to analyze bacterial and viral communities, revealing that Proteobacteria was the most dominant bacterial phylum.
  • The study identified various viral families related to vertebrates and insects, with highlights including the presence of African swine fever virus and several poxviruses, while also noting that many of the bacteria detected were newly reported genera.
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Paratuberculosis a contagious and chronic disease in domestic and wild ruminants, is caused by Mycobacterium avium subspecies paratuberculosis (MAP). Typical clinical signs include intractable diarrhea, progressive emaciation, proliferative enteropathy, and mesenteric lymphadenitis. Paratuberculosis is endemic to many parts of the world and responsible for considerable economic losses.

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Objective: To characterize two strains of street rabies virus (RABV) isolated from the brain tissue of cattle from Inner Mongolia. Differences in the histopathological and ultrastructural changes in the brain tissue of infected mice were determined to reveal variation in the pathogenesis of infection between street rabies virus strains.

Methods: Ten-day-old mice were intracranially inoculated with one of three virus strains and brain tissue harvested when the mice were moribund.

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Objective: To perform pathological observation and etiological identification of specimens collected from dairy cows, beef cattle and dogs which were suspected of rabies in Inner Mongolia in 2011, and analyze their etiological characteristics.

Methods: Pathological observation was conducted on the brain specimens of three infected animals with Hematoxylin-Eosin staining, followed by confirmation using immunofluorescence and nested RT-PCR methods. Finally, phylogenetic analysis was conducted using the virus N gene sequence amplified from three specimens.

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In order to analyze the molecular epidemiology of A (H1N1) influenza virus in 2009, the complete genome sequences of influenza strains from different host sources downloaded from the NCBI were analyzed on genetic evolution by DNAstar software in this research. The results showed that 79 mutation sites of new A (H1N1) influenza virus were observed compared to previous human A (H1N1) influenza strain, including 14 mutation sites new in all A (H1N1) influenza sources and 37 mutation sites only observed in swine strain. A significant difference was represented in antigenic sites between new A (H1N1) influenza strain and the previous human A (H1N1) strain.

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