Generalized Adaptive Cation-Selective Interfaces Exhibiting High Stability: Integrating Transduction Materials and Uniform Ion-Selective Membranes via One-Step Fabrication.

Rapidly advancing all-solid-state ion-selective electrodes are promising candidates as key components in intelligent biological and chemical sensors. Ionics sensing performance, essential for sensor stability and reliability, is influenced not only by interface compositions but by often-overlooked overall interface structures. This work develops a one-step adaptive integrated interface structure (AIIS) with high interfacial stability for analyzing general cations (K, Na, Ca, Mg, Pb, Cd, and Cu), showcasing exceptional near-Nernst response across wide linear ranges.

Inhibitions imposed by kinetic constraints of membranes in all-solid-state ion-selective electrodes: characteristics of interfacial capacitance in solid contacts.

Although various materials have been extensively studied as solid contacts in all-solid-state ion-selective electrodes, of research on kinetic phenomena at solid-solid and solid-liquid interfaces remains limited. This lack of understanding may lead to confusion between the performance of capacitors and that of electrical analysis systems, finally leading to misinterpretation of material properties. While there are established methodologies for investigating capacitive mechanisms, they all center on the energy storage properties of particular materials and lack the capability to analyze real detection systems involving membranes.

Chainmail Structures of CoNi Alloys Encapsulated in Nitrogen-Doped Carbon Nanotubes Empowered Long-Term Stable Detection of Sodium Ions.

Low potential drift is one of the performance criteria for designing all-solid-state sodium ion selective electrodes (Na-SC-ISEs), which directly affects the stability and reliability of detection results. Currently, most attempts primarily focus on improving the hydrophobicity and capacitance of solid-contact (SC) layers to enhance the stability of Na-SC-ISEs, while neglecting the important impact of the stability and capacitance retention rate of SC materials on the long-term stability of Na-SC-ISEs. Herein, chainmail-structured nanomaterials are elaborately designed, where CoNi alloys are encapsulated in nitrogen-doped carbon nanotubes (NCNTs), as SC layers for the construction of all-solid sodium ion selective electrodes.

Potential-Driven Dynamic Spring-Effect of Pd─Cu Dual-Atoms Empowered Stability and Activity for Electrocatalytic Reduction.

Atomic-level catalysts are extensively applied in heterogeneous catalysis fields. However, it is a general but ineluctable issue that active metal atoms may migrate, aggregate, deactivate, or leach during reaction processes, suppressing their catalytic performances. Designing superior intrinsic-structural stability of atomic-level catalysts with high activity and revealing their dynamic structure evolution is vital for their wide applications in complex reactions or harsh conditions.

Integrated Headband for Monitoring Chloride Anions in Sweat Using Developed Flexible Patches.

Flexible wearable potentiometric ion sensors for continuous monitoring of electrolyte cations have made significant advances in bioanalysis for personal healthcare and diagnostics. However, less attention is paid to the most abundant extracellular anion, chloride ion (Cl) as a mark of electrolyte imbalance and an important diagnostic indicator of cystic fibrosis, which has important significance for accurate monitoring in complex biological fluids. An all-solid-state Cl-selective electrode is constructed utilizing oxygen vacancies reinforced vanadium oxide with a nitrogen-doped carbon shield as the solid contact (VO@NC/Cl-ISE).

Stepwise Coordination Engineering of Pt/Au Dual Catalytic Sites with Enhanced Electrochemical Activity and Stability.

Dual-site catalysts hold significant promise for accelerating complex electrochemical reactions, but a major challenge remains in balancing high loading with precise dual-site architecture to achieve optimal activity, stability, and specificity simultaneously. Herein, a strategy of stepwise targeted coordination engineering is introduced to co-anchor Pt single atoms (Pt, 1.41 wt.

Fully Integrated Multiplexed Wristwatch for Real-Time Monitoring of Electrolyte Ions in Sweat.

Considerable progress has already been made in sweat sensors based on electrochemical methods to realize real-time monitoring of biomarkers. However, realizing long-term monitoring of multiple targets at the atomic level remains extremely challenging, in terms of designing stable solid contact (SC) interfaces and fully integrating multiple modules for large-scale applications of sweat sensors. Herein, a fully integrated wristwatch was designed using mass-manufactured sensor arrays based on hierarchical multilayer-pore cross-linked N-doped porous carbon coated by reduced graphene oxide (NPCs@rGO-950) microspheres with high hydrophobicity as core SC, and highly selective monitoring simultaneously for K, Na, and Ca ions in human sweat was achieved, exhibiting near-Nernst responses almost without forming an interfacial water layer.

Ion-Electron Transduction Layer of the SnS-MoS Heterojunction to Elevate Superior Interface Stability for All-Solid Sodium-Ion Selective Electrode.

The high selectivity and fast ion response of all-solid sodium ion selective electrodes were widely applied in human sweat analysis. However, the potential drift due to insufficient interfacial capacitance leads to the deterioration of its stability and ultimately affects the potential accuracy of ion analysis. Designing a novel ion-electron transduction layer between the electrode and the ion selective membrane is an effective method to stabilize the interfacial potential.

Interface catalytic regulation electron rearrangement and hydroxyl radicals triggered by oxygen vacancies and heavy metal ions.

Although the enhanced intrinsic activities of some nano-metal oxides are obtained by manufacturing oxygen vacancies (OVs), the effect of multiple roles of OVs is ambiguous. Herein, an interface catalytic regulation electron rearrangement and hydroxyl radicals (˙OH) was proposed with the designed ZrO hollow sphere rich in OVs (V-rich ZrO). Surprisingly, it was shown that the catalytic ability of V-rich ZrO was 9.

Generalizable Descriptors of Highly Sensitive Detection of As(III) over Transition-Metal Single Atoms: A Combined Density Function Theory and Gradient Boosting Regression Approach.

Traditional nanomodified electrodes have made great achievements in electrochemical stripping voltammetry of sensing materials for As(III) detection. Moreover, the intermediate states are complicated to probe because of the ultrashort lifetime and complex reaction conditions of the electron transfer process in electroanalysis, which seriously hinder the identification of the actual active site. Herein, the intrinsic interaction of highly sensitive analytical behavior of nanomaterials is elucidated from the perspective of electronic structure through density functional theory (DFT) and gradient boosting regression (GBR).

General Strategies to Construct Highly Efficient Sensing Interfaces for Metal Ions Detection from the Perspective of Catalysis.

Constructing high-effective electrode sensing interfaces has been considered an effective method for electrochemical detection toward heavy metal ions (HMIs). However, most research has been devoted to enhancing the stripping currents of HMIs by simply improving the adsorptive capacity and conductivity of the electrode modified materials, while lacking theoretical guidelines in fabricating catalytic sensing interfaces. Besides, the understanding of detection mechanisms is quite unscientific from the perspective of catalysis.

Growth inhibition effect of β-catenin small interfering RNA-mediated gene silencing on human colon carcinoma HT-29 cells.

The β-catenin gene is a critical component of Wnt signaling pathway. Aberrant activation of Wnt/β-catenin signaling and subsequent upregulation of β-catenin is related to enhancing cell proliferation and developing colon polyps and colon cancer. In the present study, the effect of β-catenin knockdown on the growth and survival of the human colon cancer cell line HT-29 was investigated in vitro.