3D-printed polycaprolactone combined with cartilage acellular matrix tissue engineered cartilage scaffold manufactured by low-temperature deposition manufacturing.

Introduction: Tissue-engineered cartilage provides an alternative for tissue repair and reconstruction. Composite scaffolds incorporating acellular cartilage matrix (ACM) and synthetic polymers have shown particular promise for cartilage tissue engineering applications. However, the present composite scaffold has not been considered as a clinically available application due to insufficient mechanical property or inflammatory response.

Transcranial Magneto-Acoustic Stimulation Enhances Cognitive and Working Memory in AD Rats by Regulating Theta-Gamma Oscillation Coupling and Synergistic Activity in the Hippocampal CA3 Region.

Alzheimer's disease (AD) is a progressive neurodegenerative disorder characterized by cognitive dysfunction and working memory impairment, with early hippocampal damage being a prominent feature. Transcranial magneto-acoustic stimulation (TMAS) has been shown to target specific brain regions for neuroregulation. This study investigated the effects of TMAS on cognitive function, working memory, and hippocampal CA3 neural rhythms in AD rats by specifically stimulating the hippocampal region.

Utilization of Integrated Biomimetic Groove Graft for Moderate-to-severe Saddle Nose Deformity Correction.

Background: The key to correcting moderate-to-severe saddle nose deformities is restoring septal support. Owing to the heterogeneity in the extent and severity of septal defects, constructing a cartilage framework tailored to specific conditions is challenging.

Objectives: This study aimed to introduce our procedure utilizing a novel Integrated Biomimetic Groove Graft (IBGG) technique for cartilage framework construction in the correction of moderate-to-severe saddle nose deformities and to evaluate its clinical outcomes.

Transcranial magneto-acoustic stimulation suppresses the power and coherence of beta-oscillations in parkinsonian rat model with improvement motor performance.

Objective: Transcranial magneto-acoustic stimulation (TMAS) is an innovative non-invasive technique designed for neural modulation, utilizing coupled magnetic and acoustic fields to regulate brain neural activity. Alterations in the electrophysiological activity between the motor cortex (MC) and subthalamic nucleus (STN) are implicated in the motor impairments of Parkinson's disease (PD).

Method: This study aimed to investigate the alterant electrophysiological activities in the STN-MC pathway.

Modulatory effects of transcranial magneto-acoustic stimulation on behavior and corticostriatal transmission of oscillatory activity in a mouse model of Parkinson's disease induced by MPTP.

Background: Transcranial magneto-acoustic stimulation (TMAS) is a novel noninvasive neuromodulation technology that combines ultrasound within a static magnetic field to achieve high spatial resolution and deep brain penetration. However, the effects of TMAS on neural oscillations related to motor deficits in Parkinson's disease (PD) remain poorly understood.

Objective: The objective of this study was to investigate whether TMAS could enhance the propagation and interaction of oscillatory dynamics within the corticostriatal circuit.

Finite-Size Corrections from the Subleading Magnetic Scaling Field for the Ising and Potts Models in Two Dimensions.

In finite-size scaling analyses of critical phenomena, proper consideration of correction terms, which can come from different sources, plays an important role. For the Fortuin-Kasteleyn representation of the -state Potts model in two dimensions, although the subleading magnetic scaling field, with exactly known exponent, is theoretically expected to give rise to finite-size-scaling analyses, numerical observation remains elusive, probably due to the mixing of various corrections. We simulate the O() loop model on the hexagonal lattice, which is in the same universality class as the Q=n2 Potts model but has suppressed corrections from other sources and provides strong numerical evidence for the attribution of the subleading magnetic field in finite-size corrections.

Correction-to-scaling exponent for percolation and the Fortuin-Kasteleyn Potts model in two dimensions.

The number n_{s} of clusters (per site) of size s, a central quantity in percolation theory, displays at criticality an algebraic scaling behavior of the form n_{s}≃s^{-τ}A(1+Bs^{-Ω}). For the Fortuin-Kasteleyn representation of the Q-state Potts model in two dimensions, the Fisher exponent τ is known as a function of the real parameter 0≤Q≤4, and, for bond percolation (the Q→1 limit), the correction-to-scaling exponent is derived as Ω=72/91. We derive theoretically the exact formula for the correction-to-scaling exponent Ω=8/[(2g+1)(2g+3)] as a function of the Coulomb-gas coupling strength g, which is related to Q by Q=2+2cos(2πg).

Accelerated photonic design of coolhouse film for photosynthesis via machine learning.

Controlling the suitable light, temperature, and water is essential for plant photosynthesis. While greenhouses/warm-houses are effective in cold or dry climates by creating warm, humid environments, a cool-house that provides a cool local environment with minimal energy and water consumption is highly desirable but has yet to be realized in hot, water-scarce regions. Here, using a synergistic genetic algorithm and machine learning, we propose and demonstrate a coolhouse film that regulates temperature and water for photosynthesis without requiring additional energy or water.

Transcranial magneto-acoustic stimulation enhances motor function and modulates cortical excitability of motor cortex in a Parkinson's disease mouse model.

Parkinson's disease (PD) is a neurodegenerative disorder characterized primarily by motor dysfunction. Transcranial magneto-acoustic stimulation (TMAS), an emerging non-invasive brain neuromodulation technology, is increasingly being applied in the treatment of brain diseases. However, the effects of TMAS on PD are unknown, which is not well studied.

Localized Plasmonic Structured Illumination Microscopy Using Hybrid Inverse Design.

Super-resolution fluorescence imaging has offered unprecedented insights and revolutionized our understanding of biology. In particular, localized plasmonic structured illumination microscopy (LPSIM) achieves video-rate super-resolution imaging with ∼50 nm spatial resolution by leveraging subdiffraction-limited nearfield patterns generated by plasmonic nanoantenna arrays. However, the conventional trial-and-error design process for LPSIM arrays is time-consuming and computationally intensive, limiting the exploration of optimal designs.

Constraint based Bayesian optimization of bioink precursor: a machine learning framework.

Current research practice for optimizing bioink involves exhaustive experimentation with multi-material composition for determining the printability, shape fidelity and biocompatibility. Predicting bioink properties can be beneficial to the research community but is a challenging task due to the non-Newtonian behavior in complex composition. Existing models such as Cross model become inadequate for predicting the viscosity for heterogeneous composition of bioinks.

Effects of transcranial magneto-acoustic stimulation on cognitive function and neural signal transmission in the hippocampal CA1 region of mice.

As a new means of brain neuroregulation and research, transcranial magneto-acoustic stimulation (TMAS) uses the coupling effect of ultrasound and a static magnetic field to regulate neural activity in the corresponding brain areas. Calcium ions can promote the secretion of neurotransmitters and play a key role in the transmission of neural signals in brain cognition. In this study, to explore the effects of TMAS on cognitive function and neural signaling in the CA1 region of the hippocampus, TMAS was applied to male 2-month-old C57 mice with a magnetic field strength of 0.

The low-lethal concentrations of rotenone and pyrethrins suppress the population growth of Rhopalosiphum padi.

As an important pest on winter wheat, Rhopalosiphum padi (L.) causes damage to the wheat yield by sucking plant nutrients, transmitting plant viruses and producing mildew. R.

Layered Composite Dorsal Onlay Implant for Augmentation Rhinoplasty.

The use of autologous costal cartilage in augmentation rhinoplasty is well-established. However, scenarios where costal cartilage is insufficient or patients are unwilling to undergo additional cartilage harvesting present a challenge. This study introduces a composite dorsal onlay implant, combining silicone and costal cartilage, as an effective solution.

Oxidative potential associated with reactive oxygen species of size-resolved particles: The important role of the specific sources.

Oxidative potential (OP) is a predictor of particulate matter (PM) toxicity. Size-resolved PM and its components that influence OP values can be generated from several sources. However, There is little research have attempted to determine the PM toxicity generated from specific sources.

Clinical Application of Botulinum Toxin A on Nasal Reconstruction with Expanded Forehead Flap for Asian Patients.

Background: Because of its unique advantages, frontal expansion has become a common tool for Asian nasal reconstruction, but it has the limitations of prolonging the duration and pain in the expansion area. Based on the fact that the denervation effect of botulinum toxin type A (BTX-A) has been widely used in the reconstruction of superficial organs, we hypothesized that BTX-A would shorten the length of nasal reconstruction sequence and alleviate the discomfort of patients.

Methods: A comparative retrospective study was conducted of consecutive patients underwent sequential treatment of nasal reconstruction between June 2010 and July 2012.

Tunneled Paranasal Augmentation Using Diced Autologous Costal Cartilage in Asian Rhinoplasty: A Comparative Study.

Due to the prevalence of anterior maxilla dysplasia in Asian population, paranasal concavity is a common accompaniment to low nose, but its impact on facial harmonization is often underestimated. A retrospective comparative study was conducted on patients diagnosed as low nose with paranasal concavity between June 2017 and June 2021, with a total of 56 patients followed up successfully. The control and observation groups were established according to whether the paranasal augmentation was performed.

Transcranial magneto-acoustic stimulation improves spatial memory and modulates hippocampal neural oscillations in a mouse model of Alzheimer's disease.

Introduction: In our study, we applied transcranial magneto-acoustic stimulation (TMAS), a technique based on focused ultrasound stimulation within a static magnetic field, in the APP/PS1 mouse model of Alzheimer's disease (AD) to explore the feasibility of TMAS on improving AD related spatial memory deficits and abnormal neural oscillations.

Methods: The mice treated with TMAS once daily for 21 days. We recorded local field potential signals in the hippocampal CA1 region of the mice after TMAS treatment with electrophysiology and evaluated the neural rehabilitative effect of TMAS with sharp-wave ripple (SWR), gamma oscillations during SWRs, and phase-amplitude coupling (PAC).

Rhinoplasty with Mortise-Tenon Cartilaginous Framework for Caudal Septal Cartilage Defects.

Introduction: Rhinoplasty for caudal septal cartilage defects is a challenge due to the difficulty of fixation of the grafts.

Objectives: This study presents an approach for correcting defects in caudal septal cartilage with the costal cartilaginous framework using a mortise-tenon technique.

Methods: From May 2019 through May 2022, a retrospective analysis of patients with caudal septal cartilage defects underwent rhinoplasty using a mortise-tenon cartilaginous framework by a senior surgeon was performed.

Multiphysics Modeling of Plasmon-Enhanced All-Optical Helicity-Dependent Switching.

In this work, we propose a multiphysics approach to simulate all-optical helicity-dependent switching induced by the local hot spots of plasmonic nanostructures. Due to the plasmonic resonance of an array of gold nanodisks, strong electromagnetic fields are generated within the magnetic recording media underneath the gold nanodisks. We construct a multiphysics framework considering the opto-magnetic and opto-thermal effects, and then model the magnetization switching using the Monte Carlo method.

Handheld Doppler Detection and Light Illumination for Vascular Mapping in Nasal Reconstruction.

Background: The application of the expanded forehead flap in nasal reconstruction has the advantage of being able to provide a sufficient amount of flap and can provide good aesthetic results. For an expanded forehead flap to survive, there must be adequate arterial supply and venous return. Despite this, limited studies have been conducted on preoperative vascular mapping and the design of the expanded forehead flap for nasal reconstruction.

Application of Modified V-Y Advancement Flap in Alar Base Reduction.

Background: A variety of techniques for alar base modification have been described in the literature. Limitations of these techniques include scars, recurrence, asymmetry, etc. An incorrect excision of the lateral alar wall can result in a tear-drop or Q-shaped deformity.

The Immediate Contraction of the Expanded Forehead Flap.

Introduction: Flaps contract immediately after harvest, which added difficulty to flap design. This study aims to investigate the immediate contraction rate of the expanded forehead flap used in nasal reconstruction.

Methods: Patients undergoing nasal reconstruction with expanded forehead flaps from September 2021 to January 2023 were included.