Cross-sectional and longitudinal associations of circulating bile acids and dementia: a systematic review.

Bile acids (BAs) may contribute to dementia by regulating neuroinflammation and influencing gut-brain axis signaling, especially in Alzheimer's disease (AD). However, their alterations in dementia development are rather complex and their impact on dementia risk remains inconclusive. To provide a comprehensive understanding of these associations, we systematically reviewed cross-sectional and longitudinal studies on circulating BAs and dementia.

THER: Integrative Web Tool for Tumour Hypoxia Exploration and Research.

THER: Integrative Web Tool for Tumor Hypoxia Exploration and Research.

Perception of risk of frailty among older adults with colorectal cancer: A descriptive phenomenological study.

This study, conducted from November 2023 to March 2024 in Harbin, China, explored frailty risk perceptions among 25 elderly colorectal cancer (CRC) patients using qualitative interviews and Colaizzi's method for analysis. Findings reveal that these perceptions change dynamically across different treatment stages, often deviating from medical definitions. Initially optimistic, patients later experienced increased anxiety and confusion about preventive measures.

Association Between Religious Service Attendance and Depression, Anxiety Among Older Amdo Tibetans.

Objectives: Religious service attendance has previously been associated with greater levels of well-being, as well as milder symptoms of depression and anxiety. However, few studies have explored this association within the Amdo Tibetan population. This study aims to estimate the association between religious service attendance and psychiatric symptoms among older Amdo Tibetans.

Having a monk in the family and all-cause mortality: a seven-year prospective cohort study.

Religious celibate monks at the household level possibly reduce all-cause mortality risk among non-monk older Tibetans. This study aims to investigate the association between having a celibate monk in a family and the all-cause mortality of non-monk household members in a Tibetan population. Baseline interviews were conducted for 713 agropastoral Amdo Tibetans aged ≥50 years residing in the eastern Tibetan Plateau from 2016 to 2017.

Clinical Characteristics and Influencing Factors of Feeding Intolerance After Surgery for Neonatal Necrotizing Enterocolitis.

Background: Feeding intolerance (FI) following surgery for neonatal necrotizing enterocolitis (NEC) can impact recovery and prognosis, making the early identification of FI risk essential for optimizing management and improving outcomes.

Methods: We retrospectively collected data from patients who underwent surgery for NEC between January 2013 and December 2023. Multivariate binary logistic regression was performed to identify independent factors influencing postoperative feeding intolerance.

Barriers and Facilitators of Implementing Colorectal Cancer Screening Management in China: A Mixed-Methods Study.

Background: Colorectal cancer is a major cause of cancer-related deaths in China. Timely screening is essential for reducing mortality, but implementing comprehensive programs in Chinese healthcare settings is challenging.

Objective: This study identifies barriers and facilitators to colorectal cancer screening (CRCS) in China and recommends effective implementation strategies.

Factors Associated With Colorectal Cancer Screening Behaviors Among Urban Populations in China: A Mixed-Methods Study Using the Health Belief Model.

Objective: Adherence to guideline-recommended colorectal cancer screening (CRCS) among average-risk urban populations in China remains significantly suboptimal. This mixed-methods study aimed to investigate screening behaviors and associated factors among average-risk urban populations through a multi-center approach.

Methodology: From February to July 2024, 550 participants were recruited via stratified random sampling in Harbin, China.

Zinc and melatonin mediated antimicrobial, anti-inflammatory, and antioxidant coatings accelerate bone defect repair.

Inflammation and bacterial infection are important causes of implant failure, and the development of multifunctional titanium surfaces to address these issues is an effective means of treating infected bone defects. In this study, polyphenols (EGCG) and Zn were first loaded onto the titanium surface to construct an EGCG/Zn polyphenol metal network coating. Then melatonin (MT) was loaded into the EGCG/Zn network structure to prepare the EGCG/Zn/MT composite coating.

Association between psychological resilience and body mass index in a community-based population: A cross-sectional study.

Background And Objective: While earlier studies have focused on the relationship between stress and obesity, there was a gap in understanding the potential impact of positive psychological factors, such as resilience, on obesity. By investigating the role of psychological resilience with obesity, this study aimed to address this gap and tackle obesity through a positive psychological framework.

Methods: Participants consisted of 2445 community residents from Shenzhen, China, with a mean age of 41.

Association between sleep duration and psychological resilience in a population-based survey: A cross-sectional study.

Background: The study aimed to find out the association between sleep duration and psychological resilience in a population-based survey.

Materials And Methods: A cross-sectional survey was conducted in August 2022, employing a cluster random sampling method to recruit community residents at Futian District in Shenzhen, China. A total of 2,445 participants aged 18 years and over were included in the study.

Telomere length and its association with systemic lupus erythematosus in an Asian population: A Mendelian randomization study.

Objectives: To investigate whether shorter telomere length is a causal risk factor for systemic lupus erythematosus (SLE) in the Asian population.

Methods: We applied the two-sample Mendelian randomization (MR) method to the pooled statistics from a genome-wide association study (GWAS) of 6,707 SLE cases and 16,047 controls. We selected nine single-nucleotide polymorphisms (SNPs) with genome-wide significance as instrumental variables for telomere length.