Publications by authors named "Yashdeep Pathania"

Background: Hailey-Hailey disease is an autosomal dominant blistering disorder characterized by junctional abnormalities of epidermal keratinocytes. Vesiculobullous eruptions affect the intertriginous areas of individuals with the condition. Ocular involvement associated with Hailey-Hailey disease is rare.

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Folliculitis decalvans (FD) is a rare, chronic inflammatory disorder that primarily affects the scalp, leading to scarring alopecia. The condition is classified as a primary neutrophilic cicatricial alopecia and is characterized by pustules, erosions, and scaly-crusty lesions, often associated with pain, itching, and burning sensations. The pathogenesis is not fully understood, though infection and immune dysregulation are implicated.

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Acrokeratosis verruciformis of Hopf (AVH) is a rare dermatological disorder associated with keratotic lesions primarily on the dorsal surfaces of the hands and feet, caused by a missense mutation in the ATP2A2 gene. Here, we report the case of a 24-year-old woman presenting with multiple wart-like lesions on the hands, feet, and neck over four years. A V-shaped notch on the nails indicated nail dystrophy.

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Dermatophytosis pose a significant burden on patients leading to recurrence and decreased quality of life owing to inadequate patient education and non-compliance to the treatment. There is a potential role of generative Artificial Intelligence (AI) in enhancing patient counseling by providing personalized, accessible, and consistent information and can support physician-led counseling, ultimately improving treatment adherence and outcomes.

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Article Synopsis
  • - Recent studies reveal a strong link between skin disorders and heart issues, with dermatologists often finding serious cardiac conditions like septal defects and cardiomyopathy in patients with certain genetic skin diseases.
  • - A thorough literature review was conducted using articles from PubMed and Google Scholar, focusing on various skin disorders that also show cardiac effects, including congenital diseases and drug reactions.
  • - Recognizing these cardiac manifestations is essential for proper treatment, timely interventions, and effective communication with patients about their health concerns.
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Background: Late-onset vitiligo (LOV), generally defined as vitiligo that starts at age 30 or older, presents unique diagnostic and management challenges, reflecting an intricate interplay of genetic, environmental, and societal factors.

Objectives: This review aims to elucidate the distinct aspects of LOV such as epidemiology, clinical characteristics, and treatment outcomes thereby enhancing diagnostic precision and planning management strategies.

Materials And Methods: A comprehensive literature search was conducted across multiple databases including PubMed and EMBASE, adhering to PRISMA guidelines.

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Article Synopsis
  • * It can resemble other skin disorders but is distinguishable by its unique histopathological features.
  • * Diagnosis may require a biopsy, as seen in a case where a 50-year-old female was confirmed to have DDD despite no family history or abnormal lab tests, highlighting the need for awareness of rare skin conditions in medical evaluations.
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  • Syphilitic balanitis, also known as Follmann balanitis, is a rare condition associated with primary syphilis, initially described by Eugene Follmann.
  • It involves inflammation of the glans and may present with a primary chancre and swollen lymph nodes in the groin, but can easily be confused with other types of balanitis.
  • A case of Follmann balanitis was diagnosed in a patient with secondary syphilis, confirmed through clinical signs, positive blood tests for syphilis, and effective treatment with benzathine penicillin.
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  • Chronic spontaneous urticaria (CSU) can be challenging to treat, as 10-50% of patients do not respond to typical antihistamines or even higher doses, often leading to corticosteroid use.
  • Third-line treatment options like omalizumab and cyclosporine exist but can also be ineffective for some patients.
  • Recent research suggests azathioprine may be an effective alternative, and ongoing studies are exploring additional treatment options for patients with refractory CSU.
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Background: Hirsutism is the presence of excessive terminal hair on androgen-dependent sites of the body. Lasers like Alexandrite, diode, and Nd:Yag lasers have been used for hair reduction with varying efficacy. Trichoscopy of hair is a simple noninvasive method of hair assessment.

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Article Synopsis
  • Limited literature exists on the effectiveness of emollients in treating chronic dermatophytosis, prompting a study to assess their efficacy compared to topical azoles.
  • The study involved 80 patients, divided into two groups, with group A using topical azole and group B using emollient after 6 weeks of initial treatment; clinical remission was tracked for 12 weeks.
  • Results showed no significant difference in recurrence rates between the two treatments, indicating that emollient use is as effective as topical luliconazole in maintaining remission.
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  • The study explores the psychosocial effects and financial concerns faced by women with facial hirsutism, emphasizing a lack of existing literature on the subject.
  • Using questionnaires, researchers assessed the quality of life, financial burden, and worry levels among 50 women with excessive facial hair.
  • Results indicate a high psychosocial impact (DLQI score of 15.98) and significant financial considerations related to treatment, particularly laser therapy, which was notably more burdensome than other methods.
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