Publications by authors named "Yashdeep Singh Pathania"

Background: Hailey-Hailey disease is an autosomal dominant blistering disorder characterized by junctional abnormalities of epidermal keratinocytes. Vesiculobullous eruptions affect the intertriginous areas of individuals with the condition. Ocular involvement associated with Hailey-Hailey disease is rare.

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Dermatophytosis pose a significant burden on patients leading to recurrence and decreased quality of life owing to inadequate patient education and non-compliance to the treatment. There is a potential role of generative Artificial Intelligence (AI) in enhancing patient counseling by providing personalized, accessible, and consistent information and can support physician-led counseling, ultimately improving treatment adherence and outcomes.

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Article Synopsis
  • - Recent studies reveal a strong link between skin disorders and heart issues, with dermatologists often finding serious cardiac conditions like septal defects and cardiomyopathy in patients with certain genetic skin diseases.
  • - A thorough literature review was conducted using articles from PubMed and Google Scholar, focusing on various skin disorders that also show cardiac effects, including congenital diseases and drug reactions.
  • - Recognizing these cardiac manifestations is essential for proper treatment, timely interventions, and effective communication with patients about their health concerns.
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Background: Late-onset vitiligo (LOV), generally defined as vitiligo that starts at age 30 or older, presents unique diagnostic and management challenges, reflecting an intricate interplay of genetic, environmental, and societal factors.

Objectives: This review aims to elucidate the distinct aspects of LOV such as epidemiology, clinical characteristics, and treatment outcomes thereby enhancing diagnostic precision and planning management strategies.

Materials And Methods: A comprehensive literature search was conducted across multiple databases including PubMed and EMBASE, adhering to PRISMA guidelines.

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Article Synopsis
  • * It can resemble other skin disorders but is distinguishable by its unique histopathological features.
  • * Diagnosis may require a biopsy, as seen in a case where a 50-year-old female was confirmed to have DDD despite no family history or abnormal lab tests, highlighting the need for awareness of rare skin conditions in medical evaluations.
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  • Lupus miliaris disseminatus faciei (LMDF), also called "acne agminata," is a rare skin condition characterized by small reddish-brown facial papules, particularly around the eyes.
  • A case study involved a 51-year-old woman with these papules for 1-2 months, some of which showed signs of healing, confirming LMDF upon further examination.
  • The patient was treated with systemic dapsone and topical tacrolimus, leading to improvement in her condition at the follow-up visit.
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  • Syphilitic balanitis, also known as Follmann balanitis, is a rare condition associated with primary syphilis, initially described by Eugene Follmann.
  • It involves inflammation of the glans and may present with a primary chancre and swollen lymph nodes in the groin, but can easily be confused with other types of balanitis.
  • A case of Follmann balanitis was diagnosed in a patient with secondary syphilis, confirmed through clinical signs, positive blood tests for syphilis, and effective treatment with benzathine penicillin.
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  • Chronic spontaneous urticaria (CSU) can be challenging to treat, as 10-50% of patients do not respond to typical antihistamines or even higher doses, often leading to corticosteroid use.
  • Third-line treatment options like omalizumab and cyclosporine exist but can also be ineffective for some patients.
  • Recent research suggests azathioprine may be an effective alternative, and ongoing studies are exploring additional treatment options for patients with refractory CSU.
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  • Limited literature exists on the effectiveness of emollients in treating chronic dermatophytosis, prompting a study to assess their efficacy compared to topical azoles.
  • The study involved 80 patients, divided into two groups, with group A using topical azole and group B using emollient after 6 weeks of initial treatment; clinical remission was tracked for 12 weeks.
  • Results showed no significant difference in recurrence rates between the two treatments, indicating that emollient use is as effective as topical luliconazole in maintaining remission.
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  • Chondroid syringoma is a rare, usually benign tumor that originates from sweat glands, occurring in only 0.01 to 0.098% of cases.
  • Due to its uncommon nature, it can often be misdiagnosed, so it's important to consider it as a potential cause for any slow-growing facial skin swellings.
  • The definitive diagnosis is made through histopathological examination after surgical excision, which is the standard treatment to prevent recurrence; a case of a 35-year-old with a chondroid syringoma exhibiting additional cystic components is discussed.
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  • The study explores the psychosocial effects and financial concerns faced by women with facial hirsutism, emphasizing a lack of existing literature on the subject.
  • Using questionnaires, researchers assessed the quality of life, financial burden, and worry levels among 50 women with excessive facial hair.
  • Results indicate a high psychosocial impact (DLQI score of 15.98) and significant financial considerations related to treatment, particularly laser therapy, which was notably more burdensome than other methods.
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  • This article explores the effectiveness of oral minoxidil as a treatment for various types of alopecia, highlighting its journey from topical formulations to systemic use.
  • The research involved a thorough review of existing literature, including clinical trials and case reports, to assess the role of oral minoxidil in treating different alopecia conditions.
  • The findings indicate that oral minoxidil shows promising results with fewer side effects, particularly for androgenetic alopecia and female pattern hair loss, presenting a viable alternative to topical treatments that often suffer from compliance issues.
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  • A young woman presented with skin issues around her mouth, resembling pemphigus foliaceous, which involves blistering and crusting.
  • Upon investigation, doctors discovered she actually had an underlying pancreatic cancer, despite her blood glucose and hemoglobin levels being normal.
  • This case highlights the importance of thorough diagnosis when unusual skin conditions appear, as they can sometimes indicate more serious health problems.
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