Bright Long-Wavelength Multi-State TADF Emitters.

To achieve multi-state, visible-light-excited, long-wavelength thermally activated delayed fluorescence (TADF) with high emission efficiency within a single molecular dye system remains a significant challenge. Herein, we developed a series of V-shaped emitters comprising electron-deficient benzothiadiazole and electron-rich triphenylamine (TPA) or carbazole (Cz) units, featuring small singlet-triplet energy gaps. These molecules exhibit long-wavelength TADF emission and bright luminescence in both single-molecule and aggregate states.

Conjugated Donor-Acceptor Macrocycles: Synthesis and Oxidation of -Phenylene Bridged Cyclic Tetra(benzo[][1,2,5]thiadiazole).

Here, we reported the synthesis of an -phenylene bridged cyclic tetra(benzo[][1,2,5]thiadiazole) () by stepwise Suzuki-Miyaura couplings. Subsequent oxidation of yielded a two-sided fused product , identified as an -phenylene bridged cyclic triphenyleno[1,2-:7,8-']bis([1,2,5]thiadiazole) dimer. The structures of and were confirmed by high-resolution mass spectroscopies (HRMS) and NMR techniques.

Translation, cultural adaptation, and validation of the Chinese standardized outcomes in nephrology-hemodialysis fatigue (C-SONG-HD fatigue) scale: a study of Chinese patients undergoing hemodialysis.

Objective: This study aimed to translate and culturally adapt the standardized outcomes in nephrology-hemodialysis fatigue (SONG-HD fatigue) scale and to assess the psychometric properties of the Chinese version of the SONG-HD fatigue (C-SONG-HD fatigue) scale.

Methods: Forward and back translations were used to translate the SONG-HD fatigue scale into Chinese. We used the C-SONG-HD fatigue scale to survey Chinese patients undergoing hemodialysis (HD) in China.

Malignant Tumor Purity Reveals the Driven and Prognostic Role of in Low-Grade Glioma Microenvironment.

The tumor microenvironment (TME) contributes to the initiation and progression of many neoplasms. However, the impact of low-grade glioma (LGG) purity on carcinogenesis remains to be elucidated. We selected 509 LGG patients with available genomic and clinical information from the TCGA database.

CDC20 regulates the cell proliferation and radiosensitivity of P53 mutant HCC cells through the Bcl-2/Bax pathway.

The incidence of hepatocellular carcinoma (HCC) is extremely high, and China accounts for approximately 50% of global liver cancer cases. Previous studies reported that CDC20 is involved in the occurrence and progression of a variety of malignant tumors. So, whether CDC20 will affect the development of HCC, we have conducted in-depth research on this.

LncRNA MORT Overexpression Inhibits Cancer Cell Migration and Invasion in Hepatocellular Carcinoma by Downregulating NOTCH1.

Long noncoding RNA (lncRNA) MORT is silenced in many malignancies, but its role in cancer remains hardly known. The expression of MORT and NOTCH1 was determined by real-time quantitative polymerase chain reaction and enzyme-linked immunosorbent assay, respectively. Correlation between MORT and NOTCH1 was analyzed by Pearson's correlation analysis.