Comprehensive Analysis of Immune Cell Infiltration and M2-Like Macrophage Biomarker Expression Patterns in Atrial Fibrillation.

Background: Macrophages play a crucial role in the progression of AF, closely linked to atrial inflammation and myocardial fibrosis. However, the functions and molecular mechanisms of different phenotypic macrophages in AF are not well understood. This study aims to analyze the infiltration characteristics of atrial immune cells in AF patients and further explore the role and molecular expression patterns of M2 macrophage-related genes in AF.

Icariin improves cardiac function and remodeling via the TGF-β1/Smad signaling pathway in rats following myocardial infarction.

Background: Postinfarction cardiac remodeling presents a compensatory mechanism aimed at mitigating congestive heart failure. It is distinguished by progressive dilatation and hypertrophy of the ventricular chambers, fibrotic alterations, and prolonged apoptosis of cardiomyocytes. The primary objective of this study was to assess the effects of icariin on myocardial fibrosis and ventricular remodeling in rats subjected to myocardial infarction (MI).

[Study on 4 human population genetic characters of Mongol and Han in Western inner Mongolia].

From 1998 to 2001, a sample of 2760 Mongol and Han individuals was investigated in 3 areas (Eerduosi city, Xilinguole and Bayannaoer leagues) from Inner Mongolia. Each individual was studied on 4 genetic characters (thumb type, palmar digital formular, fingernail type and plantar digital formular). The result is as follows: (1) The frequencies of the straight thumb were over 60%, and there were no significant sexual differences in all of 6 groups.