Exogenous ATP-induced lipolysis and its correlation with skeletal muscle atrophy and hepatic damage in fasting mice.

Adenosine triphosphate (ATP) is a critical energy currency in living organisms, yet its extracellular transport and efficacy as an exogenous energy source remain controversial. This study explored the effects of exogenous ATP administration on energy metabolism and tissue integrity in fasting mice. C57BL/6J mice were intraperitoneally injected with ATP at doses of 25, 50, and 100 mg/kg every 12 h during a 72-h fasting period.

Comparison of digestive capacity in broilers raised on diets with or without soybean meal.

The objective of this study was to investigate the digestive capacity of broilers raised on diets with or without soybean meal, and evaluate the impact on the determination of metabolizable energy (ME) in feed. Two hundred and eighty-eight 7-day-old Arbor Acres male broilers were divided into 6 blocks based on initial body weight (BW). Within each block, 48 broilers were randomly assigned to one of the two types of diet: a corn-soybean meal diet (CSMD) and a corn-based soybean meal-free diet (CSMFD) containing alternative plant proteins (peanut meal, cottonseed meal, and rapeseed meal).

Identification of compounds to promote diabetic wound healing based on transcriptome signature.

Purpose: Diabetic wounds are characterized by delayed healing, and the resulting diabetic foot ulcer may lead to severe complications, including amputations and mortality. This study aimed to identify potential small molecule drug candidates that can enhance diabetic wound healing through integrating transcriptome signature and experimental validation strategies.

Method: Gene expression dataset (GSE147890) from a diabetic skin humanized mice model in the Gene Expression Omnibus database was analyzed to identify differentially expressed genes between diabetic and normal skin, as well as the wound edge at 24 h.

Impact of chemical composition on metabolizable energy and its prediction models in brewer's spent grains for broilers at different ages.

This study aimed to investigate the relationship between chemical composition and metabolizable energy (ME) in brewer's spent grains (BSG), and to develop ME prediction models for fast-growing white feathered broilers at different ages. Broilers aged 11 to 14 days or 25 to 28 days were fed 11 experimental diets (one basal diet and 10 diets supplemented with BSG) in a 2 × 11 completely randomized factorial arrangement. Each experimental diet was assigned to 6 replicates of 4 broilers, either 11 to 14 days or 25 to 28 days of age.

Bol-miR168a is a key regulator of defense responses to Sclerotinia sclerotiorum in Brassica oleracea.

Overexpressing Bol-miR168a in cabbage reduces resistance to Sclerotinia sclerotiorum, highlighting its role in disease susceptibility regulation. miRNA-mediated post-transcriptional regulation plays a central role in regulating physiological processes, including plant growth and development, hormone signal transduction, and stress response. However, the underlying mechanism and function of microRNA-mediated repression, particularly in relation to conferring resistance to S.

Comparison of the characteristics of small intestinal fluid from white-feathered and yellow-feathered broilers.

The objective of this study was to compare the properties of small intestinal fluid (SIF) from white- and yellow-feathered broilers fed variable dietary CP to test the hypothesis that digestive enzymes sourced from the SIF of yellow-feathered broilers could serve as a viable alternative for preparing in vitro SIF specifically for white-feathered broilers. Ten Arbor Acres Plus broilers (32 days of age) and 20 Chinese yellow chickens (51 days of age) were fitted with jejunal cannulas and assigned to dietary treatments as follows: 1) white-feathered broilers (BW of 4.08 ± 0.

Roles of natural products on myokine expression and secretion in skeletal muscle atrophy.

Skeletal muscles serve both in movement and as endocrine organs. Myokines secreted by skeletal muscles activate biological functions within muscles and throughout the body via autocrine, paracrine, and/or endocrine pathways. Skeletal muscle atrophy can influence myokine expression and secretion, while myokines can impact the structure and function of skeletal muscles.

A comparative evaluation on the energetic values and digestibility of fatty acids in rice bran oil and palm oil for broilers.

The objective of this study was to compare the digestibility of energy and fatty acids (FA) in rice bran oil (RBO) and palm oil (PO) fed to growing Arbor Acre (AA) broilers. A corn-soybean meal basal diet and the basal diet supplemented with 8% RBO or PO were evaluated. A total of 72 AA male broilers (initial BW = 1,173 ± 6 g; age = 22 d) were randomly divided to 3 dietary treatments with 6 replicates of 4 broilers in each.

Evaluation of lipid sources and emulsifier addition on fat digestion of yellow-feathered broilers.

This study evaluated the effect of an emulsifier on the energetic values of lipids fed to yellow-feathered chickens and established prediction equations for the metabolizable energy (ME) of lipids fed with and without an emulsifier. One hundred and ninety-two Chinese yellow-feathered roosters [Wen's Yellow A; initial body weight (BW) = 2.37 ± 0.