Ratiometric Covalent Fluorescent Probes for Dynamic Super-Resolution Imaging of Mitochondrial HClO.

Dynamic monitoring of hypochlorous acid (HClO) in mitochondria is crucial for elucidating the molecular pathogenesis of ferroptosis-related diseases. Super-resolution microscopy, which surpasses the optical diffraction limit, has emerged as a powerful tool for subcellular dynamic imaging. However, the lack of mitochondrial HClO fluorescent probes with high specificity, stable labeling, low environmental interference, and negligible spectral crosstalk presents a significant challenge for achieving dynamic super-resolution imaging.

Heteroatom-free conjugated tetraphenylethylene polymers for selectively fluorescent detection of tetracycline.

The antibiotic tetracycline (Tc) is a major contaminant in food and water, with adverse effects on both ecosystems and human health. The development of novel sensors for tetracycline detection is of great importance. In this work, we develop a novel heteroatom-free conjugated tetraphenylethylene polymer (TPE-CMP) fluorescence sensor for the detection of tetracycline.

UV-assisted ultrafast construction of robust FeO/polydopamine/Ag Fenton-like catalysts for highly efficient micropollutant decomposition.

Fenton-like catalysts represent a family of promising materials to degrade micropollutants from contaminated water. However, the practical applications of Fenton-like catalysts are mainly limited by low catalytic degradation efficiency and stability. Herein, for the first time, rapid fabrication of Ag-decorated FeO/polydopamine (FPA) microspheres was achieved via the help of UV irradiation, and the designed FPA microspheres were employed as Fenton-like catalysts to degrade micropollutants.

A benzaldehyde-indole fused chromophore-based fluorescent probe for double-response to cyanide and hypochlorite in living cells.

With the rapid development of various industries, cyanide (CN) and hypochlorite (ClO) have a tremendously adverse effect on the health of humans and animals. In this study, a fluorescent probe HHTB based on a benzaldehyde-indole fused chromophore was designed to detect cyanide and hypochlorite simultaneously. The synthesized probe was found to have strong anti-interference ability.

Construction of a novel cell-trappable fluorescent probe for hydrogen sulfide (HS) and its bio-imaging application.

Fluorescence detection of HS in living organisms is greatly advantageous because it is nondestructive and can be used for in situ analysis. We have constructed a novel rhodamine analogue dye (Rho630) by extending the conjugated system of rhodamine to create a novel cell-trappable HS fluorescent probe Rho630-AM-HS with red light emission. Its application for HS fluorescence detection in living HeLa cells and zebrafish was investigated.