Association between metabolites and hepatocellular carcinoma: findings from a two-sample Mendelian randomization study.

Background: Identifying metabolic biomarkers can enhance early detection and risk stratification of hepatocellular carcinoma (HCC). We conducted a two-sample Mendelian randomization (MR) study to assess the potential causal effects of metabolites on HCC risk.

Methods: We performed meta-analyses to pool the effects of genetic instruments from 64 previously published genome-wide association studies.

Assessing the staining potential of common sauces on tooth enamel surface.

Tooth discoloration is a common esthetic concern often linked to dietary exposure to highly pigmented foods and beverages. Although the staining effects of beverages like coffee, tea, and wine have been extensively studied, less attention has been given to the staining potential of everyday condiments. This study aimed to evaluate the staining potential of eight sauces-fish sauce, curry, ketchup, sriracha, and four soy sauce varieties (Jin, Yangjo, Tsuyu, and Sashimi)-on bovine enamel specimens.

Impact of demineralization, brushing, and remineralization sequences on dentin mineral retention and surface properties.

This study investigates the effects of different treatment sequences involving demineralization, brushing, and remineralization on the calcium and phosphorus (Ca/P) content, surface roughness, and microhardness of dentin specimens. Bovine dentin samples were subjected to the following five treatment conditions: control, demineralization, demineralization followed by remineralization, demineralization followed by brushing then remineralization, and demineralization followed by remineralization then brushing. X-ray fluorescence spectroscopy was then utilized to assess the elementary composition changes, while scanning electron microscopy provided microstructural analyses.

Food impaction on three-dimensional printed models with periodontal ligament simulation.

Objective: This study aims to evaluate food impaction on three-dimensional (3D) printed models with periodontal ligament simulation.

Materials And Methods: Based on a commercial typodont pair, 3D maxillary and mandibular models were created with no teeth and with tooth sockets that were 1 mm wider than the original ones from 24 to 27 or 34 to 37 for periodontal ligament simulation with vinyl polysiloxane impression material. In total, 35 pairs of 7 combinations, including maxillary/mandibular typodonts in occlusion with maxillary/mandibular 3D models with/without a distal gap of canines on 3D models (tooth 23 or 33) were mounted on hinge articulators and divided into seven groups (n = 5).

Food Impaction in Dentistry: Revisited.

Purpose: This review aimed to highlight the aetiology and risk factors of food impaction along with the treatment in each case.

Materials And Methods: A search was conducted in PubMed from 1947 to March 28, 2023. The search terms utilised included (food impaction) OR (interdental impaction).

Assessing Microleakage at 2 Different Implant-Healing Abutment Interfaces.

Objectives: This study aimed to evaluate implants from different manufacturers and determine whether implant-healing abutment interface has a significant impact on implant seal.

Methods: An air-injection pressure measurement test was performed on implants with either line-contact (modified TSIII [TSM] and Bone Level Tapered [BLT]) or partial face-contact (BlueDiamond [BD], SuperLine [SL], ISII, and UFII) interface design from 6 different manufacturers. Forty implants per implant type were analysed.

Revisiting the Complications of Orthodontic Miniscrew.

Miniscrew has been used widely as an effective orthodontic anchorage with reliable stationary quality, ease of insertion and removal techniques, immediate or early loading, flexibility in site insertion, less trauma, minimal patient cooperation, and lower price. Nonetheless, it is not free of complications, and they could impact not only the miniscrew success rate but also patients' oral health. In this article, literature was searched and reviewed electronically as well as manually to evaluate the complications of orthodontic miniscrew.

The impact of Morse taper implant design on microleakage at implant-healing abutment interface.

The microbial leakage at the implant-abutment interface (IAI) is one cause of peri-implant infection that puts long-term implant stability at risk. The present study compared two types of Morse taper implants in terms of sealing performance at the implanthealing abutment interface. Three implant systems, one of which exhibited a partial face-contact design (TSO) and the other two a line-contact design (TSM and BLT), were analyzed in vitro using two quantitative implant leakage measuring techniques: air-injection pressure measurement test and microbial examination.

Is whitening toothpaste safe for dental health?: RDA-PE method.

The relative dentin abrasivity-profilometry equivalent values were compared using non-contact profilometry with three subtypes of regular toothpaste and two subtypes of whitening toothpaste containing sodium bicarbonate and 35% hydrogen peroxide. Bovine dentin specimens were assigned to six groups: regular toothpaste (R): R1 (BAMBOO SALT GUM OINTMENT); R2 (MEDIAN TARTAR ORIGINAL); R3 (PERIOE Alpha), Reference slurry: RS (calcium pyrophosphate), whitening toothpaste (W): W1 (NET. WT); W2 (Vussen 28 WHITENING).