Prognostic value of the combination of serial APACHE II with serum lactate for predicting post-operative mortality in gastrointestinal perforation peritonitis: a prospective cohort study.

Background: Gastrointestinal perforation peritonitis is a life-threatening surgical emergency with high mortality. Early identification of patients at increased risk of poor outcomes is critical for optimizing care. In this study, we aimed to evaluate the prognostic value of combining serial Acute Physiology and Chronic Health Evaluation II (APACHE II) scores and serial serum lactate levels in predicting 30-day postoperative mortality among patients undergoing emergency laparotomy for gastrointestinal perforation peritonitis.

Management and Outcomes of Umbilical Hernia in Decompensated Chronic Liver Disease: A Single-Unit Experience of Six Cases.

Background Complicated umbilical hernia in decompensated chronic liver disease is a significant cause of morbidity and mortality. This study evaluates the management strategies and factors predicting outcomes following emergency umbilical hernia repair. Methods A retrospective analysis was conducted on six patients with decompensated chronic liver disease who presented with complicated umbilical hernia in an emergency setting to the hepatopancreatobiliary (HPB) surgical unit between July and December 2024.

Eggshell-derived hydroxyapatite as a biomaterial in dentistry: a scoping review of synthesis, properties and applications.

Background: Hydroxyapatite (HAp) derived from chicken eggshells has recently gained significant interest in tissue engineering and regenerative medicine. This paper aims to review the synthesis, properties and applications of eggshell-derived hydroxyapatite (E-HAp) in dentistry.

Methods: A comprehensive literature search was conducted in PubMed and Scopus databases, along with a grey literature search.

Brønsted acid-promoted synthesis of highly functionalized tetrahydrocarbazoles from diethyl ()-5-diazo-4-oxohex-2-enedioate.

Brønsted acid-promoted synthesis of highly functionalized tetrahydrocarbazoles from indoles and easily accessible diethyl ()-5-diazo-4-oxohex-2-enedioate has been achieved. Diethyl ()-5-diazo-4-oxohex-2-enedioate acts as a 1,4-diacceptor and undergoes tandem Michael addition followed by nucleophilic substitution at the diazo carbon with indole in the presence of a strong Brønsted acid.

Complications With Demineralized Bone Matrix, Hydroxyapatite and Beta-Tricalcium Phosphate in Single and Two-Level Anterior Cervical Discectomy and Fusion Surgery.

Study Design: Systematic literature review.

Objectives: To analyze the evidence available reporting complications in single or two-level anterior cervical discectomy and fusion (ACDF) using a demineralized bone matrix (DBM), hydroxyapatite (HA), or beta-tricalcium phosphate (β-TCP).

Methods: A systematic review of the literature using PubMed, EMBASE, Cochrane Library, and ClinicalTrials.