Operative Treatment of Adolescent Diaphyseal Clavicle Fracture: Elastic Stable Intramedullary Nail Versus Plate Fixation.

: Adolescent diaphyseal clavicle fracture surgery has increased in recent years. However, the optimal operative method remains debated, particularly between elastic stable intramedullary nailing (ESIN) and plate fixation. This study compared postoperative outcomes and complication rates between ESIN and plate fixation for treating diaphyseal clavicle fractures in adolescent patients.

Breastfeeding, Prepubertal Adiposity, and Development of Precocious Puberty.

Importance: The incidence of central precocious puberty (CPP) is increasing globally, raising concern about its potential long-term health consequences. However, the association between early-life feeding practices and CPP is poorly understood.

Objective: To investigate the association of breastfeeding during the first 4 to 6 months of life with CPP in boys and girls and whether this association is mediated by prepubertal adiposity.

Incidence trends and perinatal risk factors of developmental dysplasia of the hip: a nationwide population-based study from South Korea.

Background And Purpose:  South Korea has implemented the National Health Screening Program for Infants and Children (NHSPIC), which includes clinical hip screening with selective hip ultrasonography beginning at 4 months of age. We aimed to investigate the trends in developmental dysplasia of the hip (DDH), associated risk factors, and growth and motor developmental outcomes up to preschool age.

Methods:  We included a retrospective, population-based birth cohort of children born between 2008 and 2015.

Physical Growth Trajectories in Children With Congenital Heart Disease: A Nationwide Study.

Background And Objectives: The growth trajectories of children diagnosed with congenital heart disease (CHD) remain unclear when analyzed through population-based data. This study examined the risk of poor growth outcomes in preschool-aged children with CHD.

Methods: This study included 325,930 children born between 2007 and 2014, of whom 65,186 were diagnosed with CHD (1,026 with complex, 2,073 with moderate, and 62,087 with simple CHD).

In Vitro Analysis of Structural Integrity and Surface Alterations of Reused Healing Abutments.

Purpose: This study aimed to investigate the changes in healing abutments (HAs) after use based on an in vitro comparison with unused HAs and to evaluate the effectiveness and clinical implications of reusing HAs.

Materials And Methods: Fifty used HAs were collected from affiliated clinics of the Department of Dentistry at Hanyang University Hospital and analyzed for surface damage, protein contamination, and microgap formation using three-dimensional laser microscopy and microcomputed tomography. The interfacial microgap between the implant and the abutment was measured at different tightening torques (5 N·cm, 10 N·cm, and 15 N·cm).

Cochlear Implantation Is Associated With Reduced Incidence of Dementia in Severe Hearing Loss.

Objectives: Hearing loss is recognized as a potentially modifiable risk factor for dementia in midlife. This study aimed to investigate the association between rehabilitation methods and dementia risk in patients with severe to profound hearing loss.

Design: Using the nationwide population data from South Korea, individuals with severe to profound hearing loss were identified.

Associations Between Ecological Determinants and Weight Status Changes Among Children from Vulnerable Populations: Empirical Findings from a National Panel Survey in South Korea.

Background: Pandemic-related weight gain disproportionately has affected children from socioeconomically disadvantaged backgrounds. However, key determinants of childhood obesity among these vulnerable children remain relatively underexplored.

Methods: In a secondary data analysis using a longitudinal dataset, the relationships between child weight status and its individual and environmental influences among vulnerable children were examined based on an ecological model.

Trends in syphilis and syphilitic uveitis among South Korean adults in 2010-2019: a nationwide cohort study.

Introduction: This study aims to investigate the epidemiology, clinical manifestations, and diagnostic and management patterns of ocular syphilis in South Korea.

Methods: This retrospective nationwide cohort study analysed health claim data from 2010 to 2019 for individuals aged ≥20 years diagnosed with syphilis, with follow-up through 2021. Age- and sex-adjusted incidence and prevalence rates were calculated for ocular conditions including anterior uveitis, posterior uveitis, panuveitis and optic neuritis.

Biomarkers for Short-Term Omalizumab Response in Chronic Spontaneous Urticaria.

Background: Omalizumab, a monoclonal antibody targeting immunoglobulin E (IgE), is approved for adults and adolescents (12 years or older) with chronic spontaneous urticaria (CSU) that does not respond to high-dose antihistamines. In Korea, there is limited research on predictive biomarkers for omalizumab response in CSU patients.

Objective: This retrospective, single-institution study aimed to identify clinical parameters predicting omalizumab response in Korean CSU patients.

Developmental screening of neurodevelopmental disorders before age 6: a nationwide health screening program.

Background: We aimed to investigate the association between developmental screening before 24 months of age and neurodevelopmental disorders (NDDs) at 4-6 years of age.

Methods: We included 922,899 newborn born between 2014 and 2016 registered in National Health Insurance Service (NHIS). Developmental screening was administered at 9-12 and 18-24 months old with the Korean Developmental Screening Test for Infants & Children (K-DST).

Obesity-related behaviors and health-related quality of life in socioeconomically vulnerable children: A cross-sectional study.

Purpose: This study aims to explore obesity-related behaviors (ORB) and health-related quality of life (HRQoL) in socioeconomically vulnerable children, while also examining potential associations between these variables.

Design And Methods: A total of 721 children enrolled in after-school care programs for socioeconomically vulnerable children participated in this study. Height (in cm) and weight (in kg) were measured directly by trained research assistants.

Timing and impact of percutaneous endoscopic gastrostomy insertion in patients with amyotrophic lateral sclerosis: a comprehensive analysis.

Dysphagia is common in amyotrophic lateral sclerosis (ALS) patients, often requiring percutaneous endoscopic gastrostomy (PEG) for enteral nutrition. We retrospectively analyzed data from 188 Korean patients with ALS who underwent PEG tube insertion at five-time points: symptom onset (t), diagnosis (t), recommended time for gastrostomy (t), PEG insertion (t), and one-year post-insertion (t). The recommended time point for gastrostomy (T for gastrostomy) was defined as the earlier time point between a weight loss of more than 10% and advanced dysphagia indicated by the ALSFRS-R swallowing subscore of 2 or less.

Monthly Variation in Bell's Palsy Based on Population Data of Korea.

Introduction: Several studies have reported that the number of patients with Bell's palsy varied significantly by month and season. However, few studies have reported the monthly variation in Bell's palsy based on the whole population. We investigated the monthly variation in Bell's palsy in Korea during a long-term period based on whole population data.

One-Year Longitudinal Changes in Tau Accumulation on [F]PI-2620 PET in the Alzheimer Spectrum.

We investigated the longitudinal changes in cortical tau accumulation and their association with cognitive decline in patients in the Alzheimer disease (AD) continuum using 2-(2-([F]fluoro)pyridin-4-yl)-9-pyrrolo[2,3-b:4,5c']dipyridine ([F]PI-2620) PET. We prospectively enrolled 52 participants (age, 69.7 ± 8.

Diabetes Mellitus and Acute Facial Palsy: A Nationwide Population-Based Study.

Introduction: Acute facial palsy, characterized by sudden hemifacial weakness, significantly impacts an individual's quality of life. Despite several predisposing factors identified for acute facial palsy, the specific relationship between diabetes mellitus (DM) and acute facial palsy has not been comprehensively explored in recent studies. The aim of the study was to assess the risk of acute facial palsy in patients with DM using a nationwide population sample cohort.

Clinical Utility of SARS-CoV-2 Rapid Antigen Test in the Emergency Department.

Background: Rapid screening for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was important in the emergency department during the coronavirus disease 2019 (COVID-19) pandemic. Real-time polymerase chain reaction (RT-PCR) is the standard method for detecting SARS-CoV-2, but it requires several hours to provide results. Instead, the rapid antigen test (RAT) has a short turnaround time and can be used at the bedside but shows low sensitivity.

Inflammatory Molecular Endotypes in Bronchiectasis: A European Multicenter Cohort Study.

Although inflammation and infection are key disease drivers in bronchiectasis, few studies have integrated host inflammatory and microbiome data to guide precision medicine. To identify clusters among patients with bronchiectasis on the basis of inflammatory markers and to assess the association between inflammatory endotypes, microbiome characteristics, and exacerbation risk. Patients with stable bronchiectasis were enrolled at three European centers, and cluster analysis was used to stratify the patients according to the levels of 33 sputum and serum inflammatory markers.

A Comparative Study of Urinary Tests and Cultures for the Effectiveness of Fosfomycin in Catheter-Related Urinary Tract Infections.

As the elderly population increases due to an aging society, the number of patients with catheters is increasing, and treatment for urinary infections is needed. The current study analyzed the effectiveness of fosfomycin, the primary antibiotic used to treat urinary tract infections (UTIs), in these patients. Patients who received fosfomycin as the primary antibiotic for a UTI were selected, and the results of urine tests and cultures before and after fosfomycin administration were compared and analyzed.

Evaluation of Paste-Type Micronized Acellular Dermal Matrix for Soft Tissue Augmentation: Volumetric and Histological Assessment in a Mouse Model.

Background: A biological injectable material, paste-type micronized acellular dermal matrix (ADM), has been proven effective in wound healing by filling defects through tissue replacement. This study aimed to compare the efficacy of paste-type micronized ADM on soft tissue augmentation with that of the conventional fillers in animal experiments.

Methods: Two distinct paste-type micronized ADMs, which were mixed with distilled water (mADM) and gelatin (mADM+GEL), respectively, were compared with conventional fillers, hyaluronic acid (HA) and polymethyl methacrylate (COL+PMMA).