Innovative modeling: a diet-induced quail model for progressive pathological changes in uric acid metabolism disorders.

Background: Diseases associated with uric acid metabolism disorders, primarily hyperuricemia, uric acid nephropathy, and gouty arthritis, are increasingly prevalent worldwide. Recent research suggests that hyperuricemia, uric acid nephropathy, and gouty arthritis can be regarded as distinct phases of the same disease, characterized by elevated serum uric acid levels and the progressive pathological manifestations observed in clinical settings. Animal models play a crucial role in investigating disease mechanisms and therapeutic interventions.

Mapping human brain topography to heart rhythms: an SEEG study.

Aims: The interplay between the heart and brain has been a subject of interest for centuries, as dysfunction in this interaction is implicated in various cardiovascular diseases and neurological disorders. Despite this advancement, there is currently a limited understanding of the mechanisms that the human brain communicates with heart rhythms. Here, we aim to characterize the human brain processing of heart rhythms and map human brain topography to heart rhythms.

Analysis of Factors Influencing the Mental Health Status of Personnel Stationed at High- and Low-Altitude Bases.

Objective: The objective of this study is to investigate and compare the mental health status of personnel stationed at high- and low-altitude bases to provide a reference for future targeted mental health education and support initiatives.

Methods: A total of 1,244 personnel posted in both high- and low-altitude bases were randomly selected using a cluster sampling method. Basic details were collected using a demographic information questionnaire, and their mental health status was assessed using the Symptom Checklist-90 (SCL-90).

Bone loss in patients with spinal cord injury: Incidence and influencing factors.

Purpose: To investigate the incidence and influencing factors of bone loss in patients with spinal cord injury (SCI).

Methods: A retrospective case-control study was conducted. Patients with SCI in our hospital from January 2019 to March 2023 were collected.

DNA Methylation Negatively Regulates Gene Expression of Key Cytokines Secreted by BMMCs Recognizing FMDV-VLPs.

Virus-like particles (VLPs) have been studied and used as vaccines to control foot-and-mouth disease (FMD). Mast cells (MCs) express various pattern recognition receptors that recognize pathogens and secrete numerous cytokines to initiate and modulate immune responses. Our previous study showed that bone marrow-derived mast cells (BMMCs) can recognize foot-and-mouth disease virus-like particles (FMDV-VLPs) to differentially express various cytokines and that histone acetylation can regulate the cytokines secreted during BMMC recognition of FMDV-VLPs.

The transformation of heavy metal speciation during rapid high-temperature aerobic fermentation of food waste and their potential mechanisms.

In this study, the content changes of multiple trace heavy metals (HMs) in food waste using a new rapid high-temperature aerobic fermentation (RTAF) technology and their relationships with different physicochemical factors were researched. The results indicated that the content of HMs in the decomposed products met the industry standards for organic fertilizers (NY/T525-2021, China). Physicochemical factors played an important role in controlling the changes in HM content.

Hip subluxation in children with spinal cord injury: Incidence and influencing factors.

Hip subluxation is a common complication in children with spinal cord injury. This study aimed to investigate the incidence and influencing factors of hip subluxation and discuss prevention strategies. Medical records of children with spinal cord injury were reviewed.

Clinical characteristics of pediatric traumatic spinal cord injury in China: A single center retrospective study.

Objective: To investigate the clinical characteristics of children with traumatic spinal cord injury (SCI) admitted to a research rehabilitation center between 2011 and 2020, with a view to generate crucial data for understanding and prevention of pediatric traumatic SCI.

Design: Retrospective cohort study.

Setting: The National Rehabilitation Research Center of China, Beijing, China.

Prognosis of traumatic spinal cord injury in children: Follow-up of 86 patients.

Purpose: The long-term situation of children with spinal cord injury (SCI) was investigated, and suggestions for helping them better return to the society were provided.

Methods: SCI patients less than 18 years old hospitalized in Beijing Boai Hospital from January 2011 to December 2020 were retrospectively analyzed. Information including motor function, complications, characteristic changes, self-care abilities, school attendance and social participation were collected by telephone interview and electronic questionnaire.

Minimum Seven-Year Follow-Up Outcomes of Percutaneous Endoscopic Lumbar Discectomy for Lumbar Degenerative Disease.

Purpose: To investigate the long-term (> 7 years) clinical outcomes of percutaneous endoscopic lumbar discectomy for lumbar degenerative disease to address postoperative problems including postoperative dysesthesia (POD), residual back pain and segmental instability.

Methods: Inclusion and exclusion criteria were established. All patients who met the above criteria were treated by PELD using the transforaminal approach.

Effect of Exercise on Cardiovascular Function Following Spinal Cord Injury: A REVIEW.

Spinal cord injury (SCI) is associated with a reduced level of physical activity, deterioration of patient body composition, metabolic profile, quality of life, and psychological functioning. As a result, risk of cardiovascular disease (CVD) increases and CVD-related death occurs at an earlier age than in individuals without SCI. Regular participation in exercise has been shown to exert beneficial effects also in patients with SCI.

Ischemic damage may play an important role in spinal cord injury during dancing.

Study Design: Retrospective analysis.

Setting: China Rehabilitation Research Center, Beijing, China.

Objective: To explore possible mechanisms underlying spinal cord injury (SCI) in children caused by hyperextension of the spine while dancing.

Adsorption of ferulic acid from an alkali-pretreated hydrolysate using a new effective adsorbent prepared by a thermal processing method.

A new adsorbent (AEPA) was prepared using the enzymatic hydrolyzed residue of rice straw in an air environment at 250 ℃ by a thermal processing method. Compared to the commercial adsorbent, AEPA possessed a larger specific surface area of 277.680 m g, and the maximum adsorption efficiency of ferulic acid from alkali-pretreated hydrolysate of rice straw achieved 70.

Heterogeneity among traumatic spinal cord injuries at the thoracolumbar junction: helping select patients for clinical trials.

Study Design: Retrospective analysis.

Setting: China Rehabilitation Research Center, Beijing, China.

Objective: A retrospective study that documents the modalities and clarifies the heterogeneity among spinal cord injuries (SCIs) caused by trauma to the thoracolumbar vertebral junction.

Clinical Predictors of Neurological Outcome within 72 h after Traumatic Cervical Spinal Cord Injury.

To investigate the prognostic values of clinical factors 72 h within traumatic cervical spinal cord injury (TCSCI). Data were extracted from the medical materials of 57 TCSCI cases. AIS was used as the outcome measure and divided into dichotomous variables by two methods, i.

Characteristics and rehabilitation for patients with spinal cord stab injury.

[Purpose] The objective of the study was to compare the incidence, diagnosis, treatment, and prognosis of patients with spinal cord stab injury to those with the more common spinal cord contusion injury. [Subjects] Of patients hospitalized in China Rehabilitation Research Center from 1994 to 2014, 40 of those having a spinal cord stab injury and 50 with spinal cord contusion were selected. [Methods] The data of all patients were analyzed retrospectively.

Comparison Between Posterior Short-segment Instrumentation Combined With Lateral-approach Interbody Fusion and Traditional Wide-open Anterior-Posterior Surgery for the Treatment of Thoracolumbar Fractures.

The aim of the study was to compare the radiographic and clinical outcomes between posterior short-segment pedicle instrumentation combined with lateral-approach interbody fusion and traditional anterior-posterior (AP) surgery for the treatment of thoracolumbar fractures.Lateral-approach interbody fusion has achieved satisfactory results for thoracic and lumbar degenerative disease. However, few studies have focused on the use of this technique for the treatment of thoracolumbar fractures.