Publications by authors named "Shiavax Rao"

Right atrial thrombus is a rare complication of hemodialysis catheter with an incidence of <6 %. New-onset atrial fibrillation can be the first symptom of catheter-related right atrial thrombus (CRAT) in a patient with long-term dialysis catheter. Therefore, evaluation for CRAT is justified in such scenario.

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Septic arthritis commonly occurs due to gram-positive cocci and usually presents as acute monoarticular swelling and tenderness, often associated with systemic signs of sepsis. In rare scenarios, a gram-positive bacillus, can cause septic arthritis. We present a rare case of native joint septic arthritis caused by in an immunocompetent patient.

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This review explores the critical role of exercise as a non-pharmacological intervention in managing ischemic cardiomyopathy (ICM), a leading cause of heart failure. It highlights the profound cardiovascular benefits of exercise, such as improved cardiopulmonary parameters, decreased morbidity and mortality, and enhanced functional capacity. It also critically evaluates existing literature on the efficacy of various exercise types and intensities, including aerobic, resistance, and high-intensity interval training.

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Artificial intelligence (AI) has emerged as a transformative tool in healthcare through data analysis, pattern recognition and predictive modeling capabilities. AI-driven approaches have the potential to positively transform patient care through personalized treatment regimens comprising antiplatelet and anticoagulant therapy. This review explores the integration of AI in guiding antithrombotic therapies, highlighting the potential to improve patient outcomes through personalized medicine.

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The prevalence of premature atherosclerotic cardiovascular disease (ASCVD) ranges from 7% to 30%, but the incidence in young patients is increasing. Traditional risk factors, such as hypertension, hyperlipidemia, obesity, and diabetes, have an increasing prevalence in young patients and especially in young women. A 32-year-old woman presented with dyspnea and exertional chest pain.

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Most patients with heart failure exhibit ventricular dyssynchrony, which is addressed by cardiac resynchronization therapy, traditionally through the use of biventricular pacing (BVP) devices. Despite this, around 30% of patients do not achieve the desired clinical outcome, and echocardiographic findings show that some patients deteriorate even further. Conduction system pacing (CSP) is a more physiologic pacing technique and includes his-bundle pacing (HBP) and left bundle branch area pacing (LBBAP).

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Hypertrophic cardiomyopathy (HCM) is an inherited condition characterized by left ventricular, non-dilated hypertrophy in the absence of another secondary underlying cause. There has been an ongoing increase in the diagnosis of HCM over the past couple of decades, prompting further work in the area of pharmacological and interventional therapies. This scoping review aimed to summarize the traditional therapeutic options for HCM and to explore emerging research on novel cardiac myosin inhibitors (CMIs) as a new option for pharmacologic management of HCM.

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Although previously considered rare, spontaneous coronary artery dissection (SCAD) is increasingly recognized as an important cause of myocardial infarction in young women. We present three unique cases of SCAD: A 46-year-old woman with a history of trigeminal neuralgia and anxiety presenting elevated troponin-I and chest pain. A 36-year-old woman with recent miscarriage presenting with diffuse T wave inversions and elevated troponin-I.

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Acute pericarditis is a common inflammatory disorder with several causes including infection, malignancy, acute myocardial infarction, and autoimmune disease. Acute pericarditis can rarely present in the setting of thyrotoxicosis. A 65-year-old man with a past medical history of HIV, diastolic dysfunction, and prediabetes presented with positional chest pain, respiratory distress, and altered mentation.

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Although percutaneous coronary intervention (PCI) has radically transformed the scope of treating coronary artery disease with stenting, stent thrombosis (STh) remains a feared complication. Very late STh, a rare complication after PCI, refers to STh occurring greater than one year after post-stent implantation. An even rarer phenomenon, "very" very late stent thrombosis (VVLST), is described in the literature as STh occurring more than five years post-stent implantation.

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We present an interesting and complex case of cardiac tamponade due to uremic pericarditis (UP), resolving with intensive hemodialysis (HD). HD should be considered as first line management for patients with UP and pericardial effusion. Intensification of HD should be considered based on clinical presentation and severity of presentation.

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Article Synopsis
  • Artificial Intelligence (AI) is a new technology that can help doctors in heart care units by looking at large amounts of data quickly.
  • A study was done to check how AI is being used in caring for heart patients, focusing on various types of treatments and support.
  • The review found 38 studies showing that while AI is still developing, it could be very helpful in making healthcare better for heart patients.
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Artificial Intelligence, specifically advanced language models such as ChatGPT, have the potential to revolutionize various aspects of healthcare, medical education, and research. In this narrative review, we evaluate the myriad applications of ChatGPT in diverse healthcare domains. We discuss its potential role in clinical decision-making, exploring how it can assist physicians by providing rapid, data-driven insights for diagnosis and treatment.

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Several studies have linked calcification of the thoracic and lower extremity arterial trunks to an increased risk of developing coronary artery disease (CAD). Calcifications of the radial and/or ulnar artery are regularly identified in hand/wrist x-rays; however, the clinical relevance of these findings as related to identifying subclinical CAD is not well understood. Associations between CAD and upper extremity calcifications have been reported, but the timeline is unclear.

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Article Synopsis
  • * Imaging indicated a loculated left-sided pleural effusion, and diagnostic thoracentesis confirmed the presence of Clostridia, leading to a diagnosis of empyema and subsequent surgical intervention.
  • * The patient also had acute cholecystitis, suggesting that the Clostridia infection may have originated from the abdomen, and he was successfully treated with laparoscopic cholecystectomy and antibiotics, highlighting the importance of prompt diagnosis and treatment.
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Background: Ultrasound can overcome barriers to visualizing the internal jugular vein, allowing hepato-jugular reflux and jugular venous pressure measurement. We aimed to determine operating characteristics of the ultrasound hepato-jugular reflux and ultrasound jugular venous pressure predicting right atrial and pulmonary capillary occlusion pressures.

Methods: In a prospective observational cohort at three US academic hospitals the hepato-jugular reflux and jugular venous pressure were measured with ultrasound before right heart catheterization.

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Article Synopsis
  • Direct lightning strikes can lead to severe injuries, impacting multiple organ systems, and the prognosis varies based on injury severity.
  • A 35-year-old man suffered a direct lightning strike while in a portable toilet, leading to unresponsiveness and requiring extensive medical intervention, including CPR and vasopressor support.
  • Despite initial recovery, he ultimately succumbed to multi-organ failure due to complications like myocardial damage, lactic acidosis, and extensive burns.
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Article Synopsis
  • Non-contrast enhanced chest CT has low sensitivity for detecting acute aortic dissection, while CT Angiography is the preferred diagnostic method.
  • A case of a young immunocompromised man with acute abdominal pain and renal injury showed that subtle findings on a non-contrast CT indicated possible aortic dissection.
  • Key non-contrast CT findings that suggest aortic dissection include aneurysmal dilation and displaced calcified intimal flaps, which were ultimately confirmed by CT angiography in this patient.
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Cardiogenic shock is a critical condition of low cardiac output resulting in insufficient systemic perfusion and end-organ dysfunction. Though significant advances have been achieved in reperfusion therapy and mechanical circulatory support, cardiogenic shock continues to be a life-threatening condition associated with a high rate of complications and excessively high patient mortality, reported to be between 35% and 50%. Extracorporeal membrane oxygenation can provide full cardiopulmonary support, has been increasingly used in the last two decades, and can be used to restore systemic end-organ hypoperfusion.

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To evaluate preconception health and adverse pregnancy outcome (APO) awareness in a large population-based registry. We examined data from the Fertility and Pregnancy Survey of the American Heart Association Research Goes Red Registry to questions regarding prenatal health care experiences, postpartum health, and awareness of the association of APOs with cardiovascular disease (CVD) risk. Among postmenopausal individuals, 37% were unaware that APOs were associated with long-term CVD risk, significantly varying by race-ethnicity.

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Article Synopsis
  • - Hypertrophic cardiomyopathy (HCM) is a common genetic heart disease, with obstructive HCM causing significant symptoms due to increased pressure in the heart's outflow tract.
  • - Current treatments like beta-blockers and calcium channel blockers have limited effectiveness, while new cardiac myosin inhibitors (CMIs) show promise for both obstructive and non-obstructive HCM patients.
  • - As research advances, other potential therapies include drugs targeting sodium channels, myocardial function, and gene therapy, suggesting a hopeful future for HCM management.
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Landiolol is an ultra-short-acting, highly cardio-selective, β-blocker, that is currently approved for clinical use in Japan and the European Union, for the treatment of tachyarrhythmias. Landiolol is highly cardio-selective with high β1 selectivity and receptor affinity, resulting in a more potent chronotropic effect and less potent hypotensive effect compared with other β-blockers such as esmolol and propranolol. Based on the recent randomized controlled trials, low-dose landiolol may have a beneficial role in the prevention and management of postoperative atrial fibrillation following noncardiac and cardiac surgeries, including on-pump and off-pump coronary artery bypass grafting and valve surgery.

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The mechanism of arterial thrombosis in coronavirus disease 2019 (COVID-19) is not completely understood and is attributed to the complex interactions of endothelial injury, platelet hyperactivation, and activated pro-inflammatory cytokines. Management strategies may include a combination of surgery and anticoagulation, or anticoagulation alone. A 56-year-old woman with recent COVID-19 infection presented with chest pain and dyspnea.

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Background: Information on reproductive experiences and awareness of adverse pregnancy outcomes (APOs) and cardiovascular disease (CVD) risk among pregnancy-capable and post-menopausal individuals has not been well described. We sought to evaluate preconception health and APO awareness in a large population-based registry.

Methods: Data from the Fertility and Pregnancy Survey of the American Heart Association Research Goes Red Registry (AHA-RGR) were used.

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