Acta Ophthalmol
July 2025
Purpose: Neovascular age-related macular degeneration (AMD) is a major cause of vision loss. Effective treatment requires sustained care, which may be influenced by continuity of care (COC). Understanding this association is crucial for improving patient outcomes.
View Article and Find Full Text PDFIntroduction: The introduction of immune checkpoint inhibitor (ICI) therapy in lung cancer has improved survival rates, leading to its widespread use. However, there has been a recent increase in case reports of tuberculosis (TB) disease occurrence following ICI treatment. The objective of this study was to ascertain whether the incidence of TB disease is elevated in the ICI group compared to the group receiving platinum-based chemotherapy among all lung cancer patients.
View Article and Find Full Text PDFBMC Musculoskelet Disord
May 2025
Purpose: To evaluate machine learning-based survival model roles in predicting rehospitalization after hip fractures to improve reduce the burden on the healthcare system.
Methods: This retrospective cohort study examined 718 patients with hip fractures hospitalized at the Daejeon Eulji Medical Center between January 2020 and June 2022. Demographic and clinical variables, and rehospitalization data were collected at 6 weeks and 3, 6, 12, and 24 months.
Rational design of catalytic nanomaterials is essential for developing high-performance fuel cell catalysts. However, structural degradation and elemental dissolution during operation pose significant challenges to achieving long-term stability. Herein, the development of multi-grained NiPt nanocatalysts featuring an atomically ordered NiPt phase within intragrain is reported.
View Article and Find Full Text PDFOphthalmic Epidemiol
May 2025
Purpose: Although the associations between cardiovascular diseases and cerebrovascular diseases with visual impairment have been documented, the relationship between cardio-cerebrovascular disease (CCVD) and visual impairment remains unclear. Thus, we aimed to investigate the association between visual impairment and the risk of CCVD among older adults in South Korea.
Methods: This study included 20,398 individuals registered in the Korean National Health Insurance Service-Elderly Cohort between 2005 and 2019.
Background: While lung function is known to decrease after suffering from pulmonary tuberculosis (TB), little is known about whether baseline lung function is associated with the occurrence of TB in the general population. This study aimed to evaluate the risk of incident TB according to baseline lung function.
Methods: A nationwide population-based cohort study was conducted using a database derived by cross-referencing Korea National Health and Nutrition Examination Survey and National Health Insurance Service between 2010 and 2016.
Unlabelled: The purpose of this study is to scientifically and systematically investigate the clinical effectiveness of a fracture liaison service (FLS) for patients with femoral fractures.
Methods: The international databases Ovid-MEDLINE, EMBASE, and The Cochrane Library and the Korean databases KISS, RISS, KoreaScience, Koreamed, and Kmbase were used. Risk of bias assessment was conducted at the study design level, and meta-analysis utilized both random-effects and fixed-effects models, along with subgroup analysis.
Backgroud: The purpose of our study was to analyze the effects of hospital volume and region on in-hospital and long-term mortality, direct medical costs (DMCs), and length of hospital stay (LOS) in elderly patients following hip fracture, utilizing nationwide claims data.
Methods: This retrospective nationwide study sourced its subjects from the Korean National Health Insurance Review and Assessment Service database spanning from January 2011 to December 2018. A generalized estimating equation model with a Poisson distribution and logarithmic link function was used to estimate adjusted odds ratios (aORs) and 95% CIs to assess the association of hospital volume with in-hospital and 1-year mortality, DMCs, and LOS.
To reduce long hospitalization durations and the high rate of compulsory psychiatric hospitalization in Korea, a revision of the Mental Health Welfare law was passed and implemented in 2017. This study quantitatively analyzed changes in hospitalization use behavior of patients with psychotic and mood disorders after revision of the Mental Health Welfare law in South Korea. The intervention time was June 2017.
View Article and Find Full Text PDFPurpose: We aimed to examine the regional disparities in secondary fracture incidence among patients with hip fractures in South Korea.
Methods: This observational, retrospective, cohort study was conducted using data of 6,213 South Korean nationals from the National Health Insurance Service-National Sample Cohort (2004-2019). Secondary fractures included hip, wrist, humerus, spine, ankle, and pelvis fractures that occurred 6 months after hip fracture.
Purpose: The objective of this study was to assess postoperative direct medical expenses and medical utilization of elderly patients who underwent either hemiarthroplasty (HA) or internal fixation (IF) for treatment of a femoral intertrochanteric fracture and to analyze differences according to surgical methods and age groups.
Materials And Methods: Data from the 2011 to 2018 Korean National Health Insurance Review & Assessment Service database were used. Risk-set matching was performed for selection of controls representing patients with the same sex, age, and year of surgery.
JMIR Public Health Surveill
May 2024
Background: As income and health are closely related, retirement is considered undesirable for health. Many studies have shown the association between pension and health, but no research has considered the association between contribution-based public pensions or their types and health.
Objective: This study investigates the association between the type of contributory public pension and depressive symptoms among older adults.
Background: The objective of our study was to analyze the postoperative direct medical expenses and hospital lengths of stay (LOS) of elderly patients who had undergone either hemiarthroplasty (HA) or total hip arthroplasty (THA) for femoral neck fractures and to determine the indication of THA by comparing those variables between the 2 groups by time.
Methods: In this comparative large-sample cohort study, we analyzed data from the 2011 to 2018 Korean National Health Insurance Review and Assessment Service database. The included patients were defined as elderly individuals aged 60 years or older who underwent HA or THA for a femoral neck fracture.
J Gerontol A Biol Sci Med Sci
May 2024
Background: Although the role of the vascular component in the pathophysiology of Parkinson's disease is widely accepted and retinal vascular abnormalities are commonly observed in Parkinson's disease patients, evidence connecting retinal vascular disorders with the risk of developing Parkinson's disease is limited. We aimed to investigate the association between retinal vascular occlusion (RVO) and the risk of developing Parkinson's disease in people over 60 years using a nationwide cohort.
Methods: From the 14-year South Korean National Health Insurance Service-Senior cohort, 11 210 incident RVO patients and 11 210 propensity scores, risk-matched controls were included.
Background: Acute pancreatitis may increase the risk of pancreatic cancer, although this association remains unclear. Therefore, we aimed to investigate this association.
Methods: We retrospectively analyzed the 2002-2019 Korean National Health Insurance Service-National Sample Cohort using 1:3 propensity score matching for sex and age (acute pancreatitis, n = 4,494; matched controls, n = 13,482).
Background: Among the older adults, hearing impairment is a common problem and may contribute to dementia.
Objective: Therefore, we aimed to examine the association between hearing impairment and the risk of dementia among older adults in South Korea.
Methods: Using the Korean National Health Insurance Service-Senior Cohort from 2005 to 2019, we collected data of 44,728 patients.
Clin Orthop Surg
December 2023
Background: The objective of this study was to analyze the direct medical expenses of a vertebral fracture cohort (VC) and a matched cohort (MC) over 5 years preceding and following the fracture, analyze the duration of the rise in medical expenses due to the fracture, and examine whether the expenses vary with age group, utilizing a national claims database.
Methods: Subjects with vertebral fractures and matched subjects were chosen from the National Health Insurance Service Sample cohort (NHIS-Sample) of South Korea. Patients with vertebral fractures were either primarily admitted to acute care hospitals (index admissions) or those who received kyphoplasty or vertebroplasty during the follow-up period (2002-2015).
Objectives: This study investigated the association between sudden sensorineural hearing loss (SSNHL) and the risk of cardio-cerebrovascular disease (CCVD) among older adults in South Korea.
Methods: Data from 38,426 patients in the Korean National Health Insurance Service-Senior Cohort from 2002 to 2019 were collected. The risk of CCVD includes both stroke and acute myocardial infarction.
Post-traumatic stress disorder (PTSD) is associated with the development of dementia; however, the association of dementia risk with overall stress-related disorders is less known. This study investigated the association between stress-related disorders and the risk of dementia in a Korean nationwide sample cohort. The data analyzed in this study were acquired from the Korean National Health Insurance Service National Sample Cohort between 2002 and 2013.
View Article and Find Full Text PDFTob Induc Dis
September 2023
Introduction: Although previous studies have addressed the association between smoking and obstructive sleep apnea (OSA), there are few studies on the association between electronic cigarette use and OSA. Thus, we aimed to evaluate the association between the dual use of electronic and conventional cigarettes and OSA.
Methods: Data from 7350 participants of the 2019-2021 Korean National Health and Nutrition Examination Survey were analyzed in this population-based study.
Introduction: The aim of our study is to analyze the association of usage and type of warming device with the risk of surgical site infection (SSI) in patients who underwent hip arthroplasty, and to analyze the factors that increase the risk of SSI if the warming device is not used.
Materials And Methods: This retrospective cross-sectional study identified subjects from data of "Evaluation of the Appropriate Use of Prophylactic Antibiotics". Included patients were defined as those who underwent elective unilateral hip hemiarthroplasty or total hip arthroplasty (THA).
Objectives: We aimed to evaluate the effect of dementia on the 1-year all-cause mortality in elderly patients who underwent hip fracture surgery, using a nationwide cohort in Korea.
Design, Setting, And Participants: This was a nationwide, retrospective study. Elderly patients (≥60 years) with and without dementia who underwent hip fracture surgery between January 2005 and December 2012 were distinguished using the data from the Korean National Health Insurance Service-Senior cohort.