Early and accurate Alzheimer's disease (AD) diagnosis is critical for effective intervention, but it is still challenging due to neurodegeneration's slow and complex progression. Recent studies in brain imaging analysis have highlighted the crucial roles of deep learning techniques in computer-assisted interventions for diagnosing brain diseases. In this study, we propose AlzFormer, a novel deep learning framework based on a space-time attention mechanism, for multiclass classification of AD, MCI, and CN individuals using structural MRI scans.
View Article and Find Full Text PDFMultimed Tools Appl
May 2025
One of the highly focused areas in the medical science community is segmenting tumors from brain magnetic resonance imaging (MRI). The diagnosis of malignant tumors at an early stage is necessary to provide treatment for patients. The patient's prognosis will improve if it is detected early.
View Article and Find Full Text PDFThis study introduces a reproducible pipeline for classifying Alzheimer's Disease from structural brain MRI utilizing a joint transformer architecture that integrates Vision Transformer and Time-Series Transformer models. The proposed framework uses pre-trained ViT for feature extraction from 2D slices of MRI volumes, followed by sequential modeling with a transformer-based classifier to capture inter-slice dependencies. The method is evaluated on the ADNI dataset, involving both binary (AD vs.
View Article and Find Full Text PDFPurpose: Alzheimer's disease (AD), a neurodegenerative disorder, is a condition that impairs cognition, memory, and behavior. Mild cognitive impairment (MCI), a transitional stage before AD, urgently needs the development of prediction models for conversion from MCI to AD.
Method: This study used machine learning methods to predict whether MCI subjects would develop AD, highlighting the importance of biomarkers (biological indicators from neuroimaging, such as MRI and PET scans, and molecular assays from cerebrospinal fluid or blood) and non-biomarker features in AD research and clinical practice.
Heart disease is the leading cause of death worldwide, and cardiac function as measured by ejection fraction (EF) is an important determinant of outcomes, making accurate measurement a critical parameter in PT evaluation. Echocardiograms are commonly used for measuring EF, but human interpretation has limitations in terms of intra- and inter-observer (or reader) variance. Deep learning (DL) has driven a resurgence in machine learning, leading to advancements in medical applications.
View Article and Find Full Text PDFHeart disease is the leading cause of death worldwide, and cardiac function as measured by ejection fraction (EF) is an important determinant of outcomes, making accurate measurement a critical parameter in PT evaluation. Echocardiograms are commonly used for measuring EF, but human interpretation has limitations in terms of intra- and inter-observer (or reader) variance. Deep learning (DL) has driven a resurgence in machine learning, leading to advancements in medical applications.
View Article and Find Full Text PDFAlzheimer's disease (AD), a neurodegenerative disease that mostly affects the elderly, slowly impairs memory, cognition, and daily tasks. AD has long been one of the most debilitating chronic neurological disorders, affecting mostly people over 65. In this study, we investigated the use of Vision Transformer (ViT) for Magnetic Resonance Image processing in the context of AD diagnosis.
View Article and Find Full Text PDFBattle Royale Optimizer (BRO) is a recently proposed optimization algorithm that has added a new category named game-based optimization algorithms to the existing categorization of optimization algorithms. Both continuous and binary versions of this algorithm have already been proposed. Generally, optimization problems can be divided into single-objective and multi-objective problems.
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