Arabidopsis root defense barriers support beneficial interactions with rhizobacterium Pseudomonas simiae WCS417.

Plant roots interact with pathogenic and beneficial microbes in the soil. While root defense barriers block pathogens, their roles in facilitating beneficial plant-microbe associations are understudied. Here, we examined the impact of specific root defense barriers on the well-known beneficial association between Arabidopsis thaliana and the plant growth-promoting rhizobacterium Pseudomonas simiae WCS417.

Investigation of Current Effect of Suspended Graphene Pressure Sensor.

The current effect of passive devices is crucial for device testing. The current effect of a suspended graphene pressure sensor in the range of 0-2 mA is studied in this paper. The results show that the resistance of graphene films and the piezoresistive effect of devices exhibit stable performance within the current threshold range of 400 μA and 300 μA, respectively.

Biomarker Screening by LCMS and Liquid Chip Technology in Acute Aortic Dissection.

Background: Aortic dissection (AD) is a serious disease. Previous study, the use of peripheral blood biomarkers to diagnose AD showed strong clinical feasibility, but the possible molecular mechanism is unclear.

Methods: Sera from 79 healthy subjects, 73 patients with well-established AD, and 74 patients with well-established acute myocardial infarction (AMI) were investigated by Liquid Chromatograph-Mass Spectrometer to detect metabolites (AFMK, Glycerophosphocholine, Inosine, SPH).

Development of Hydrophobic Coal-Fly-Ash-Based Ceramic Membrane for Vacuum Membrane Distillation.

Membrane distillation is an emerging separation technology with a high separation factor in water desalination. Ceramic membranes are increasingly used in membrane distillation because of high thermal and chemical stabilities. Coal fly ash is a promising ceramic membrane material with low thermal conductivity.

Nutrient Availability Does Not Affect Community Assembly in Root-Associated Fungi but Determines Fungal Effects on Plant Growth.

Nonmycorrhizal root-colonizing fungi are key determinants of plant growth, driving processes ranging from pathogenesis to stress alleviation. Evidence suggests that they might also facilitate host access to soil nutrients in a mycorrhiza-like manner, but the extent of their direct contribution to plant nutrition is unknown. To study how widespread such capacity is across root-colonizing fungi, we surveyed soils in nutrient-limiting habitats using plant baits to look for fungal community changes in response to nutrient conditions.

LncRNA MALAT1 Promotes STAT3-Mediated Endothelial Inflammation by Counteracting the Function of miR-590.

The excessive production of inflammatory mediators by vascular endothelial cells (ECs) greatly contributes to the development of atherosclerosis. In this study, we explored the potential effect of lncRNA MALAT1 on endothelial inflammation. First, the EC inflammation model was constructed by treating human umbilical vein ECs (HUVECs) and human coronary artery ECs (HCAECs) with oxidized low-density lipoprotein (ox-LDL), which confirmed the role of MALAT1 in the inflammatory activity.

Electrical and histological remodeling of the pulmonary vein in 2K1C hypertensive rats: Indication of initiation and maintenance of atrial fibrillation.

Objective: Hypertension is a significant risk factor for atrial fibrillation (AF). The role of pulmonary vein (PV) remodeling in the mechanistic association between hypertension and AF is not definitive. In this study, we aimed to identify changes in the electrophysiology and histology in PVs in two-kidney, one-clip (2K1C) hypertensive rats.

Electropharmacological properties of telmisartan in blocking hKv1.5 and HERG potassium channels expressed on Xenopus laevis oocytes.

Aim: The objectives of this study were to investigate the inhibitory action of telmisartan, a selective angiotensin II type 1 receptor antagonist, on hKv1.5 and human ether-a-go-go-related gene (HERG) channels expressed on Xenopus laevis oocytes.

Methods: hKv1.