Publications by authors named "Ruey-Pyng Ng"

The use of cryoablation for B3 fibroepithelial lesions (FELs) of the breast has not been well-documented. Cryoablation offers several advantages over surgery in treating breast masses, including avoidance of general anesthesia, less invasiveness, shorter recovery, and greater cost-effectiveness. This prospective study reported the outcome of a patient with a breast B3 FEL treated with cryoablation.

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Background: Breast cancer is one of the most prevalent cancers among women and significantly impacts psychological well-being and health-related quality of life (HR-QoL) during the perioperative period. Mobile health interventions offer a promising approach to providing education and psychosocial support, yet their effectiveness in this context remains underexplored.

Objective: This study aimed to develop and evaluate the effectiveness of an innovative, mobile-based, perioperative care program for women undergoing breast cancer surgery (iCareBreast).

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Introduction: In breast cancer patients undergoing mastectomy without reconstruction, an external breast prosthesis could aid patients' recovery, improve body image and confidence by helping to regain a symmetrical chest appearance when dressed. However, external breast prosthesis preferences among Asian breast cancer patients were not widely studied. We aimed to compare patients' experience with the conventional commercially manufactured standard-sized (small, medium, large, extra-large) bra and prosthesis versus customized hand-knitted external breast prosthesis with patient's bra after unilateral mastectomy at a tertiary hospital.

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Background: One of the manifestations of recurrence after mastectomy is the presentation of chest wall lesion. However, it is unclear if the size of the chest wall recurrence (CWR) is related to the presence of simultaneous systemic metastasis in these patients. We aimed to determine if the size of the CWR could affect the outcome in these patients.

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Background: National Comprehensive Cancer Network (NCCN) guidelines on the axillary management of breast cancer patients with isolated chest wall recurrence after mastectomy are unclear. Though sentinel lymph node biopsy (SLNB) is possible and may be considered, there is limited data on its usefulness. We aimed to determine if axillary restaging surgery was required in this cohort of patients who developed operable isolated chest wall recurrences after mastectomy.

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Introduction: Little is known about second recurrences in breast cancer patients, especially in patients with mastectomy. We aimed to determine the risk factors, prevalence and patterns of second recurrence in mastectomy patients after first recurrence.

Methods: Stage I-III breast cancer patients treated at a tertiary institution from 1st September 2005 to 31st October 2017 and developed first and second recurrences after mastectomy were retrospectively reviewed.

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Background: In breast cancer patients fulfilling the Z0011 trial criteria, axillary lymph node dissection (ALND) is reserved for patients with a high nodal burden of ≥3 metastatic nodes. In this group of patients, to avoid an ALND, neoadjuvant chemotherapy (NACT) could be given instead to achieve nodal pathological complete response (pCR). However, the benefit of NACT in achieving nodal pCR and avoiding ALND in this group of patients is unknown.

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Article Synopsis
  • Current teaching methods for oncoplastic surgery marking face challenges, such as difficulty in recruiting volunteers and limitations of existing anatomical models, leading to the development of the Marking Breast Oncoplastic Surgery Simulator (MBOSS).
  • In a study involving 40 participants, those trained with MBOSS demonstrated significantly higher post-test knowledge scores compared to those trained with volunteers, though overall skill application showed no major differences after six months.
  • Feedback revealed that 95% of MBOSS-trained participants found the simulator useful, with 85% expressing a preference for it over using a volunteer, indicating MBOSS as a viable alternative for training in oncoplastic surgery marking.
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Lessons Learned: Removal of sonographically abnormal (up to 3) metastatic clipped nodes, without sentinel lymph node biopsy, could accurately predict axillary status in breast cancer patients receiving neoadjuvant chemotherapy. ypT and the first clipped node status were statistically significant factors for nodal pathologic complete response. This novel approach requires validation in larger studies.

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Introduction: Oncoplastic breast-conserving surgery (OBCS) can cause breast asymmetry. Although contralateral breast surgery to achieve symmetry was offered to these patients, the uptake of symmetrisation was variable. We aimed to determine the factors that deter patients with breast cancer undergoing OBCS from opting for symmetrisation.

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Article Synopsis
  • The Skin Mark clipped Axillary nodes Removal Technique (SMART) can improve the accuracy of sentinel node biopsies in breast cancer patients who have undergone neoadjuvant chemotherapy by effectively removing clipped nodes.
  • A study involving 25 clipped nodes in 14 patients showed that SMART had a 100% success rate for the UltraCor Twirl clip and varying success rates for other clips, with ultrasound visibility being a key factor.
  • Overall, SMART is feasible and promising for clipped node removal, especially for patients with fewer and less deeply seated nodes, though larger studies are needed to confirm these findings.
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We present the first reported video of milk fistula. Milk fistula is a rare complication secondary to abscess or breast intervention in lactating women. It is a clinical diagnosis and the treatment is usually conservative, which included cessation of breastfeeding, with a good prognosis.

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Background: Use of mammoplasty for resection of large non-malignant tumours is not widely described. We aim to determine the optimal tumour to breast size ratio cut-off in this group of patients undergoing mammoplasty which could achieve satisfactory cosmetic outcomes.

Methods: Patients who underwent mammoplasty from May 2014 to June 2017 for biopsy-proven large non-malignant tumours were included in the study.

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Background: Although oncoplastic breast surgery is used to resect larger tumors with lower re-excision rates compared to standard wide local excision (sWLE), criticisms of oncoplastic surgery include a longer-albeit, well concealed-scar, longer operating time and hospital stay, and increased risk of complications. Round block technique has been reported to be very suitable for patients with relatively smaller breasts and minimal ptosis. We aim to determine if round block technique will result in operative parameters comparable with sWLE.

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