Micromachines (Basel)
May 2025
Molybdenum disulfide (MoS) has gained attention for its promising gas-sensing capabilities due to its high surface area and tunable electronic properties. In this study, we investigate the time-dependent growth (under constant conditions) of sputtered MoS films on ZnO nanorods and their impact on NO sensing performance. ZnO nanorods, synthesized via a hydrothermal method, provide a high-surface-area template to enhance charge transport and gas adsorption.
View Article and Find Full Text PDF, a member of the complex (MTBC), has emerged as a significant contributor to tuberculosis (TB) in cattle, wildlife, and humans. However, understanding about its pathogenesis and severity is limited, compounded by the lack of reliable TB biomarkers in cattle. This study delves into the comparative pathology and transcriptomic landscape of pulmonary granulomas in cattle naturally infected with , using high-throughput RNA sequencing.
View Article and Find Full Text PDFEval Program Plann
August 2025
The global threat of dengue has burdened the health systems of underdeveloped and developing countries. In such a scenario, a 'community training program' has become the only remedy for vector-borne diseases like dengue. The absence of any anti-viral therapy or licensed vaccination for dengue fever further underlines the importance of an awareness program.
View Article and Find Full Text PDFEarly interactions between tubercle bacilli and lung cells are critical in tuberculosis (TB) pathogenesis. Conventional two-dimensional cell cultures fail to replicate the multicellular complexity of lungs. We introduce a three-dimensional pulmosphere model for Mycobacterium tuberculosis infection in bovine systems, demonstrating through comprehensive transcriptome and proteome analyses that these multicellular spheroids closely mimic lung cell diversity, interactions, and extracellular matrix (ECM) composition.
View Article and Find Full Text PDFThe pink boll worm now became a menace for sustainable cultivation of Bt cotton in India. Based on the data recorded in unsprayed conditions at 13 different locations of north, central and south cotton growing zone between 2007 and 2023, initiation of green boll damage during later part of the season was observed on Bt cotton genotype during 2009-2014 wherein incidence of PBW already existed on non-Bt genotype. In our research, between 2014 and 2017, the central and southern regions of India experienced a rise in the survival of pink bollworms on Bt cotton surpassing the Economic Threshold Level (ETL) whereas in the north zone PBW incidence started in 2018 at experimental locations.
View Article and Find Full Text PDFTuberculosis (TB) remains a major chronic infectious disease in cattle, particularly challenging in India which hosts the world's largest and most diverse cattle population farmed in close proximity to its human settlements. This study investigates the hypothesis that genetic and immune variations drive differential TB susceptibility in cattle breeds. Using comprehensive transcriptomic analyses, we examined immune responses in peripheral blood mononuclear cells (PBMCs) from Sahiwal and Sahiwal-Holstein Friesian (SHF) crossbred cattle.
View Article and Find Full Text PDFIndian J Pharmacol
September 2024
For a robust Pharmacovigilance system in a country, training of healthcare professionals is of utmost importance. The training is the integral part of continual improvement in any quality management system. The present article describes the different training modules and experience from the Pharmacovigilance Programme of India (PvPI) and emphasizes that if training and education elements with special reference to pharmacovigilance are implemented for all concerned stakeholders in a healthcare system, the efficiency of deliverables will be improved and objectives of the organization can easily be achieved.
View Article and Find Full Text PDFThe accelerated rise in antimicrobial resistance (AMR) poses a significant global health risk, necessitating the exploration of alternative strategies to combat pathogenic infections. Biofilm-related infections that are unresponsive to standard antibiotics often require the use of higher-order antimicrobials with toxic side effects and the potential to disrupt the microbiome. Probiotic therapy, with its diverse benefits and inherent safety, is emerging as a promising approach to prevent and treat various infections, and as an alternative to antibiotic therapy.
View Article and Find Full Text PDFThe inorganic perovskite CsPbI shows promising photophysical properties for a range of potential optoelectronic applications but is metastable at room temperature. To address this, Br can be alloyed into the X-site to create compositions such as CsPbIBr that are stable at room temperature but have bandgaps >1.9 eV - severely limiting solar applications.
View Article and Find Full Text PDFThe whitefly, (Gennadius), is a polyphagous and major pest of cotton worldwide. Both adults and nymphs of affect the crop by causing direct and indirect damage. A severe whitefly outbreak was experienced during 2015 on cotton in North India and this was followed by a profound infestation during 2022.
View Article and Find Full Text PDFIndia is the world's largest cotton producer and the only country that grows all four cultivated cotton species. There have been very few studies on the diversity and abundance of natural enemies of cotton insect pests in these cultivated cotton species. Therefore, the current study (2016-2018) was conducted to assess the diversity and abundance of natural enemies that cultivated cotton species harbour.
View Article and Find Full Text PDFTuberculosis (TB) in the bovine is one of the most predominant chronic debilitating infectious diseases primarily caused by . Besides, the incidence of TB in humans due to , and that in bovines (bovine TB, bTB) due to - indicates cattle as a major reservoir of zoonotic TB. While India accounts for the highest global burden of both TB and multidrug-resistant TB in humans, systematic evaluation of bTB prevalence in India is largely lacking.
View Article and Find Full Text PDFGen Psychiatr
March 2023
Nicotine use is more prevalent in patients with psychiatric disorders, especially those diagnosed with psychotic illnesses. Previously, this higher prevalence has been partially attributed to the potential ameliorative effects of nicotine on symptom severity and cognitive impairment. Some healthcare professionals and patients perceive there is a beneficial effect of nicotine on mental health.
View Article and Find Full Text PDFUnlabelled: Deep vein thrombosis (DVT) is a preventable complication of critical illness, and this guideline aims to convey a pragmatic approach to the problem. Guidelines have multiplied over the last decade, and their utility has become increasingly conflicted as the reader interprets all suggestions or recommendations as something that must be followed. The nuances of grade of recommendation vs level of evidence are often ignored, and the difference between a "we suggest" vs a "we recommend" is overlooked.
View Article and Find Full Text PDFPharmaceutical pollution that imposes a health threat worldwide is making accurate and rapid detection crucial to prevent adverse effects. Herein, binder-free zinc oxide nanograins on carbon cloth (ZnO NGs@CC) have been synthesized hydrothermally and employed to fabricate a flexible electrochemical sensor for the quantification of hydroxychloroquine (HCQ) that is typical pharmaceutical pollution. The characteristics of ZnO NGs@CC were investigated by various in-depth electron microscopic, spectroscopic and electroanalytical approaches.
View Article and Find Full Text PDFVirusdisease
December 2022
Background: Severe acute respiratory syndrome Coronavirus-2 invades the cells via ACE2 receptor and damages multiple organs of the human body. Understanding the pathological manifestation is mandatory to endure the rising post-infection sequel reported in patients with or without comorbidities.
Materials And Methods: Our descriptive review emphasises the direct, indirect and post-infection damages due to COVID-19.
Neotrop Entomol
August 2022
Entomopathogens (EPFs) are potential alternatives to chemical insecticides for managing Bemisia tabaci (Genn.), an invasive pest of the cotton crop. EPFs alone may not always provide enough insect pest control, but combining EPFs with pesticides, provided both components are compatible, can make an integrated pest management program considerably more effective.
View Article and Find Full Text PDFIn this work, the effects of gamma-ray irradiation (up to 3 kGy) on the structural and electronic properties of poly(3,4-ethylenedioxythiophene):poly(styrenesulfonate) (PEDOT:PSS), irradiated in air and vacuum environments are systematically investigated. Raman spectroscopy indicates that there is no significant change in structural conformation of PEDOT:PSS film after gamma-ray irradiation. However, the conductivity of the film decreases as a function of dose in both air and vacuum environments, which can be deduced as a result of defects created in the structure.
View Article and Find Full Text PDFJ Psychiatr Pract
January 2022
Anti-N-methyl-D-aspartate (anti-NMDA) receptor encephalitis is a condition that was only identified relatively recently. It often presents in psychiatric settings, with clinical presentations that may overlap with those of other psychiatric disorders such as psychoses secondary to schizophrenia, substance use, or brief delusional disorder. It often presents in women of child bearing age and has a relatively high mortality rate.
View Article and Find Full Text PDFThe increasing coincidence of obesity with heart failure may preclude eligibility for orthotopic heart transplantation, requiring continuous-flow left ventricular assist devices (LVADs) as destination therapy. This report describes intraoperative considerations for patients who underwent LVAD implantation with concurrent laparoscopic sleeve gastrectomy (LSG) to promote weight loss. In particular, right ventricular dysfunction associated with acute left ventricular unloading may be compounded by pneumoperitoneum for LSG due to the difficulty in ventilating patients with obesity, hypercarbia-mediated increase in pulmonary vascular resistance, and variable cardiac loading conditions.
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