Novel Enterococcus phage BUCT630: Isolation and genomic insights targeting drug-resistant Enterococcus faecium in vitro and in vivo.

The antibiotic-resistant Enterococcus faecium (E. faecium) is a significant health issue requiring alternative therapies. Phages could be an alternative to antibiotics and have promising activity in both in vitro and in vivo experiments.

Psychosomatic and Psychological Impact of Hepatitis C: A Cross-Sectional Study of Depression, Fibrosis, and Somatic Symptoms in Treatment-Naive and Treatment-Experienced Patients Who Achieved Sustained Virologic Response.

Background: Hepatitis C virus (HCV) infection is associated with neuropsychiatric symptoms, including depression and psychosomatic complaints. While direct-acting antivirals (DAAs) have revolutionized HCV treatment, their impact on mental health and systemic symptoms remains unclear. This study aimed to compare depression severity, liver fibrosis scores, and psychosomatic symptoms in treatment-naive (Tx-naive) and treatment-experienced (Tx-experienced) patients who achieved sustained virologic response (SVR).

Current velocity, water quality, and benthic taxa as predictors for coral recruitment rates on the Great Barrier Reef.

Coral reefs worldwide are experiencing frequent disturbances, rendering coral recruitment critical for population recovery. This large-scale study identifies environmental, spatial, and biotic drivers of coral recruit densities at 141 stations stratified across seven regions and three depths (1, 5, and 15 m depths) with contrasting environmental conditions across and along the Great Barrier Reef and the Torres Strait. Settlement tiles were deployed for two years, with coral densities and benthic cover quantified following retrieval.

Assessment of the potential and application of BeO nanocage for removal of ciprofloxacin from water employing density functional theory.

The modern world is facing the issue of emerging pollutants for its sustainable development. We report a detailed study on the abatement of ciprofloxacin (CIP) by BeO nanocage. Five different geometries of BeO nanocage with CIP i.

Unveiling the potential of aluminum-decorated 3D phosphorus graphdiyne as a catalyst for NO reduction.

Interest in single-atom catalysts (SACs) has surged due to their potential to mitigate greenhouse NO gas from the environment. In this study, we explore the potential of NO reduction using porous 3D phosphorus graphdiyne decorated with an Al atom (3D-Al/PGDYN) through density functional theory. Results confirm the energetic stability of Al decorations on 3D-PGDYN and indicate that the Al atom plays an active role in catalysis.

Fog-assisted de-duplicated data exchange in distributed edge computing networks.

The Internet of Things (IoT) generates substantial data through sensors for diverse applications, such as healthcare services. This article addresses the challenge of efficiently utilizing resources in resource-scarce IoT-enabled sensors to enhance data collection, transmission, and storage. Redundant data transmission from sensors covering overlapping areas incurs additional communication and storage costs.

Interactive Malaysian Childhood Healthy Lifestyle (i-MaCHeL) programme: a single-arm pilot study.

Background: The growing obesity epidemic in Malaysia presents a public health challenge that requires innovative intervention strategies. In an effort to address this problem, an Interactive Malaysian Childhood Healthy Lifestyle (i-MaCHeL) programme, which is a web-based initiative designed for preschool child-parent dyads offers a novel approach. Nevertheless, the success of such a web-based intervention depends on several interrelated factors.

Efficient detection of nitric oxide a biomarker associated with COVID19 via N, P co-doped C fullerene: a computational study.

Context: Coronavirus (COVID-19) is a novel respiratory viral infection, causing a relatively large number of deaths especially in people who underly lung diseases such as chronic obstructive pulmonary and asthma, and humans are still suffering from the limited testing capacity. In this article, a solution is proposed for the detection of COVID-19 viral infections through the analysis of exhaled breath gasses, i.e.

An intelligent diabetes classification and perception framework based on ensemble and deep learning method.

Sugar in the blood can harm individuals and their vital organs, potentially leading to blindness, renal illness, as well as kidney and heart diseases. Globally, diabetic patients face an average annual mortality rate of 38%. This study employs Chi-square, mutual information, and sequential feature selection (SFS) to choose features for training multiple classifiers.

Genomic Exploration: Unraveling the Intricacies of Indica Rice L. Germin-Like Protein Gene 12-3 (GLP12-3) Promoter via Cloning, Sequencing, and Analysis.

Germin and Germin-like proteins (GLPs) are a class of plant proteins that are part of the Cupins superfamily, found in several plant organs including roots, seeds, leaves, and nectar glands. They play a crucial role in plant defense against pathogens and environmental stresses. Herein, this study focused on the promoter analysis of GLP12-3 in rice cultivar Swat-1 to elucidate its regulation and functions.

Synthesis of hydrazone-based polyhydroquinoline derivatives - antibacterial activities, α-glucosidase inhibitory capability, and DFT study.

In recent years, polyhydroquinolines have gained much attention due to their widespread applications in medicine, agriculture, industry, Here, we synthesized a series of novel hydrazone-based polyhydroquinoline derivatives multi-step reactions. These molecules were characterized by modern spectroscopic techniques (H-NMR, C NMR, and LC-HRMS) and their antibacterial and α-glucosidase inhibitory activities were assessed. Compound 8 was found to be the most active inhibitor against NCTC 5348, IM 622, , and ATCC 6337 with a zone of inhibition of 15.

A bromide substituted 2D additive for stable and efficient perovskite photovoltaics.

In this article, a bromide substituted 2D layered perovskite having a repeated vertical orientation and coexisting with the bulk of a 3D perovskite is reported for the first time. This novel structure is obtained through controlled compositional engineering of the perovskite precursor solution. The photovoltaic performance of this novel 2D/3D perovskite was higher than that of 3D MAPbI and a maximum photoconversion efficiency (PCE) of 17.

Systematic surface bowing in 2D III-nitride monolayers.

In this article we report novel composite materials of bucky ball (C fullerene) and III-nitrides (BN, AlN, GaN, InN). The experimental feasibility of the novel composite materials is confirmed through negative binding energies and molecular dynamics simulations performed at 500 K. The structural properties of the novel composites are explored through density functional theory.

Advanced Tree-Based Techniques for Predicting Unconfined Compressive Strength of Rock Material Employing Non-Destructive and Petrographic Tests.

The accurate estimation of rock strength is an essential task in almost all rock-based projects, such as tunnelling and excavation. Numerous efforts to create indirect techniques for calculating unconfined compressive strength (UCS) have been attempted. This is often due to the complexity of collecting and completing the abovementioned lab tests.

Validation of a Novel RP-HPLC Technique for Simultaneous Estimation of Lignocaine Hydrochloride and Tibezonium Iodide: Greenness Estimation Using AGREE Penalties.

Herein, we reported an HPLC method for the simultaneous determination of tibezonium iodide (TBN) and lignocaine hydrochloride (LGN). The method was developed according to the International Conference for Harmonization guidelines (ICH) Q2R1 using Agilent 1260 with a mobile phase consisting of acetonitrile and phosphate buffer (pH 4.5) in a volumetric ratio of 70:30 and flowing through a C Agilent column at 1 mL/min.

A New Method for Determination of Optimal Borehole Drilling Location Considering Drilling Cost Minimization and Sustainable Groundwater Management.

Drilling boreholes for the exploration of groundwater incurs high cost with potential risk of failures. However, borehole drilling should only be done in regions with a high probability of faster and easier access to water-bearing strata, so that groundwater resources can be effectively managed. However, regional strati-graphic uncertainties drive the decision of the optimal drilling location search.

A Prospective Multicenter Randomized Controlled Trial to Evaluate the Efficacy of Chitosan Hydrogel Paste in Comparison to Commercial Hydroactive Gel as a Wound Bed Preparation.

 This clinical trial aimed to evaluate the clinical efficacy of chitosan derivative hydrogel paste (CDHP) as a wound bed preparation for wounds with cavities.  This study enrolled 287 patients, with 143 patients randomized into the CDHP group (treatment) and 144 patients randomized into the commercial hydroactive gel (CHG) group (control). The granulation tissue, necrotic tissue, patient comfort, clinical signs, symptoms, and patient convenience during the application and removal of the dressing were assessed.

Anodic SnO Nanoporous Structure Decorated with CuO Nanoparticles for Sensitive Detection of Creatinine: Experimental and DFT Study.

Advanced anodic SnO nanoporous structures decorated with CuO nanoparticles (NPs) were employed for creatinine detection. Anodization of electropolished Sn sheets in 0.3 M aqueous oxalic acid electrolyte under continuous stirring produced complete open top, crack-free, and smooth SnO nanoporous structures.

An interactive Malaysian Childhood Healthy Lifestyle (i-MaCHeL) intervention programme to change weight-related behaviour in preschool child-parent dyads: Study protocol of a cluster randomised controlled trial.

Introduction: Unhealthy weight, especially childhood obesity, is emerging as a growing epidemic and a challenge in developed and developing countries. Partnership with parents to promote healthy lifestyle changes may have a lifelong impact on weight-related outcomes in children. This study aims to determine the efficacy of an Interactive Malaysian Childhood Healthy Lifestyle (i-MaCHeL) intervention programme to change weight-related behaviour in preschool child-parent dyads.

The Fate of Coracoid Graft after Latarjet Procedure: Arthroscopic and Open Findings of Graft Union and Glenoid Remodelling.

Successful Latarjet procedures depend on many factors including graft union and subsequent restoration of the glenoid surface. Coracoid graft union has been studied; however, remodelling of the glenoid has not been studied extensively. We present two Latarjet cases in which coracoid screws were removed due to hardware issues, at 12 months postoperatively in one patient and at six months in another.

Instability analysis of spin-electron-acoustic waves and the appearance of separated spin electron cyclotron mode in spin-polarized magnetized quantum plasma.

Linear and nonlinear characteristics of electrostatic waves are studied in a magnetized plasma consisting of spin-up (n_{↑}) and spin-down (n_{↓}) state populations with uniformly distributed static ions in the background. The linear analysis shows the existence of four modes. One of these modes, termed the separated spin electron cyclotron wave, is found to be due to the separated spin populations.

An Efficient Multi-Scale Convolutional Neural Network Based Multi-Class Brain MRI Classification for SaMD.

A brain tumor is the growth of abnormal cells in certain brain tissues with a high mortality rate; therefore, it requires high precision in diagnosis, as a minor human judgment can eventually cause severe consequences. Magnetic Resonance Image (MRI) serves as a non-invasive tool to detect the presence of a tumor. However, Rician noise is inevitably instilled during the image acquisition process, which leads to poor observation and interferes with the treatment.