Eur Arch Otorhinolaryngol
August 2025
Objective: This systematic review evaluated the diagnostic accuracy of large language models (LLMs) in otolaryngology-head and neck surgery clinical decision-making.
Data Sources: PubMed/MEDLINE, Cochrane Library, and Embase databases were searched for studies investigating clinical decision support accuracy of LLMs in otolaryngology.
Review Methods: Three investigators searched the literature for peer-reviewed studies investigating the application of LLMs as clinical decision support for real clinical cases according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines.