Bioherbicidal and cytogenotoxic potential of nanoemulsions containing essential oils from Piper amalago and Piper dilatatum.

Essential oils offer a viable alternative to traditional agrochemicals, mitigating problems such as environmental contamination and weed resistance. However, application faces challenges such as low solubility in water and rapid environmental degradation. To overcome these limitations, nanoemulsions containing essential oils from Piper amalago L.

Compromised minds: cognitive decline in a social insect correlates with parasitism status.

Parasites can influence host physiology and behavior, often impairing cognition. We investigated how infection and parasite load affect olfactory learning and memory in the paper wasp Polistes dominula workers parasitized by the insect parasite Xenos vesparum (Strepsiptera). We adapted a Pavlovian conditioning assay based on the proboscis extension reflex protocol.

Factors influencing the response to periodontal therapy in patients with diabetes: post hoc analysis of a randomized clinical trial using machine learning.

Objective: To evaluate factors influencing the response to periodontal therapy in patients with periodontitis and type 2 diabetes mellitus (DM) using machine learning (ML) techniques, considering periodontal parameters, metabolic status, and demographic characteristics.

Methodology: We applied machine learning techniques to perform a post hoc analysis of data collected at baseline and a 6-month follow-up from a randomized clinical trial (RCT). A leave-one-out cross-validation strategy was used for model training and evaluation.

Comparison of the Aquatic Therapy Protocols on Gait of Children With Cerebral Palsy: A Randomized Controlled Trial.

Objective: To analyze and compare the effects of 2 aquatic exercise protocols on the gait of children with cerebral palsy (CP), aged 6 to 8 years.

Methods: A randomized, controlled, and blind clinical trial, carried out with 16 children with CP classified to Gross Motor Function Classification System (GMFCS) II and III bilateral spastic, divided into a group of aquatic balance exercises group (BG) and a group of aquatic trunk exercises group (TG). The following assessments were completed before and after the intervention: 6-Minute Walk Test (6MWT), Trunk Control Measurement Scale, Pediatric Balance Scale, Timed Up and Go, Dynamic Gait Index, and Child Health Questionnaire-Parent form 50.

Water, Health, and Social Technologies: One Million Cisterns Programme Case Study.

This paper focuses on the impacts of climate change on vulnerable ecosystems and its implications for the health and well-being of populations. It specifically examines the semi-arid region of Brazil, where the introduction of a social climate adaptation tool, cisterns, has brought about significant positive changes. Cisterns, a low-cost climate adaptation technology, can be replicated globally, reducing the negative health impacts of frequent droughts, especially for vulnerable groups in remote rural areas.

Unveiling the Effect of Aqueous-Phase Dynamics on Chitosan Hydrogel Film Mechanical Properties Through AFM Nanoindentation and Tensile Testing.

The mechanical properties of cell scaffolds are strongly influenced by their hydration state. In this study, we investigated the effect of the aqueous phase on the elastic modulus of chitosan hydrogel films using two complementary techniques: uniaxial tensile testing and atomic force microscopy (AFM) nanoindentation. Our results demonstrate that hydration markedly reduced the elastic modulus, decreasing from approximately 2 GPa in dry films to 120 kPa in swollen films, primarily due to the plasticizing effect of water.

Seasonal and nutritional modulation of honeybee olfactory learning by the short neuropeptide F.

Neuropeptides are crucial molecules in the nervous system, regulating various biological processes. Neuropeptide F (NPF) and its shorter form, short neuropeptide F (sNPF), serve functions in invertebrates analogous to those of neuropeptide Y (NPY) in vertebrates, modulating growth, reproduction, nociception, circadian rhythms and feeding behaviours. In the honeybee, a social insect that adjusts foraging strategies based on colony needs, sNPF is a key regulator of foraging-related behaviours, including food intake, sucrose sensitivity, olfactory perception and visual memory formation.

Ac Hydrogel Modulates IL-1β-Driven Inflammation via Mast Cell-Associated and Immune Regulatory Pathways in Diabetic Wounds.

Chronic, non-resolving inflammation is a major contributor to impaired wound healing in diabetes. Annexin A1 (AnxA1), a pro-resolving mediator, and its mimetic peptide Ac have demonstrated therapeutic potential in modulating inflammatory responses. In this study, we evaluated the effects of topical Ac hydrogel in a streptozotocin-induced diabetic wound model.

Social representations of COVID-19 by the nursing team of an intensive care unit.

Introduction: COVID-19 was a new psychosocial phenomenon that affected the work context of healthcare professionals, particularly intensive care nursing teams, impacting their ways of being and relating.

Aim: The aim of this study was to analyze the structure and process of the production of social representations of nursing professionals who worked in intensive care settings during the COVID-19 pandemic.

Method: Qualitative research, based on the theory of social representations.

Validation of Management Zones, Variability, and Spatial Distribution of the Physiological Quality of Soybean Seeds.

Precision agriculture facilitates improved management by studying the spatial and temporal variability of soil attributes. Soybean ( (L.) Merrill) seeds may exhibit distinct quality when produced in different management zones.

Impact of SGLT2i on Cardiac Remodeling and the Soleus Muscle of Infarcted Rats.

Unlabelled: Skeletal muscle changes occur in heart failure (HF). Despite the cardioprotective effects of sodium-glucose co-transporter 2 (SGLT2) inhibitors in HF, their impact on skeletal muscle remains poorly understood. We investigated the effects of the SGLT2 inhibitor empagliflozin (EMPA) on cardiac remodeling and the soleus muscle of rats with myocardial infarction (MI)-induced HF.

Efficacy of Botulinum Toxin Applied Immediately After Wound Closure on Scars Quality Assessment: A Systematic Review and Meta-analysis.

Background: Botulinum toxin (BTX) is considered an efficient and safe therapy for postoperative scars that improves visual and functional quality. However, the optimal timing for injection remains under debate due to conflicting evidence.

Objective: The aim of this study is to evaluate the efficacy and safety of BTX applied immediately after wound closure in the quality assessment of postoperative scars.

Applying NLP methods to code functional performance in electronic health records using the international classification of functioning, disability, and health.

Background: Clinical records often provide information on a person's functioning (activities), reflecting their lived experience of health. Automated extraction using clinical natural language processing (cNLP) can assist providers with clinical decision-making, treatment planning, predicting health outcomes, and informing health care policy.

Objective: We aim to (1) describe the applicability of the World Health Organization's International Classification of Functioning, Disability and Health (ICF) to development of cNLP tools, (2) identify key challenges in application of the ICF, and (3) offer recommendations to improve this process.

Accuracy of CT Scan for Detecting Posterior Ligamentous Complex Injury in Traumatic Thoracolumbar Fractures: A Systematic Review and Meta-Analysis.

Study DesignA systematic review and meta-analysis.ObjectivesThis systematic review and meta-analysis aim to evaluate the diagnostic accuracy of CT in detecting PLC injuries in traumatic thoracolumbar fractures.MethodsA comprehensive search of PubMed/MEDLINE, Embase, and Web of Science was conducted up to January 2025.

Neuromusculoskeletal modeling of spasticity: A scoping review.

Introduction: This scoping review aimed to provide an overview of neuromusculoskeletal models used to investigate the mechanisms underlying spasticity and identify issues to be addressed in future models.

Materials And Methods: We followed the Preferred Reporting Items for Systematic Reviews and Meta-Analysis Extension for Scoping Reviews (PRISMA-ScR) guidelines and searched four bibliographic databases (PubMed, Compendex Engineering Village, IEEE Xplore, and Science Direct). Inclusion criteria were original studies written in English that investigated the underlying mechanisms of spasticity in humans with no age restrictions.

Comparison of Diagnostic Methods for Respiratory Disease in Calves Used on Farms With Thoracic Radiography.

The most commonly used techniques in the field are the pulmonary auscultation, Wisconsin score (WI), California score (CA), and pulmonary ultrasonography. However, with the exception of the latter, no studies have compared thoracic radiography with other possible techniques in calves. Therefore, the objective of the study was to compare and verify the agreement between clinical score techniques, pulmonary auscultation, and ultrasonographic and radiographic evaluations, considering the latter as reference test.

Effectiveness of the Ticket to Work program in supporting employment among adults with disabilities.

Background: Returning to work benefits many people with disabilities, as it supports personal financial independence and provides opportunities for greater societal contributions. The U.S.

Trends and Future Projections in Ultrasonic Welding Research for Hybrid Materials.

Ultrasonic welding has gained interest from various researchers and industries worldwide, particularly for joining dissimilar materials in sectors such as aerospace, aeronautics, and electronics. This paper presents a comprehensive bibliometric review aimed at mapping the evolving landscape of ultrasonic welding research. Through the systematic analysis of 1913 scientific documents, it identifies key advances, challenges, and future directions in the field.

Chryseobacterium indologenes sepsis in a pediatric patient.

Chryseobacterium indologenes is a Gram-negative aerobic bacillus commonly found in nosocomial environments, particularly in patients with prolonged hospital stays or those requiring long-term invasive devices. It primarily affects elderly and immunocompromised individuals. This microorganism is associated with multidrug resistance, which is a crucial factor in treatment decisions.

Effectiveness and Safety of Edoxaban in the Routine Clinical Care of Atrial Fibrillation Patients in Brazil: Prospective 1-Year Follow-Up Study - EdoBRA.

Background: Edoxaban, an orally administered anticoagulant, has been shown to be safe and effective in preventing stroke in atrial fibrillation (AF) patients. Given its widespread use since approval, evaluating edoxaban's real-world performance in the Brazilian clinical context is crucial.

Objective: The study aimed to report the one-year safety and effectiveness of edoxaban in AF patients in Brazil.

Development of sustainable electrodes based on cobalt ferrite-decorated biochar for the voltammetric determination of paracetamol in biological fluids.

Biochars (BC) obtained from biomass residues have been highlighted in electroanalytical applications for their distinct physicochemical properties and for making the devices cheaper and sustainable. In this work, we propose the use of BC derived from forest residues of eucalyptus, decorated with cobalt ferrite (CoFeO), as a modifying agent for carbon paste electrodes aimed at the voltammetric sensing of paracetamol (PAR) in biological fluids. BC was obtained by pyrolysis (450 °C, 72 h) and then decorated with CoFeO synthesized co-precipitation.

Green synthesis, characterization, and antimicrobial activity of silver nanoparticles from water-soluble fractions of Brazilian Kefir.

Nanotechnology offers promising new avenues for combating drug-resistant pathogens. Given its antioxidant capacity, the water-soluble fraction of Brazilian kefir was hypothesized to serve as an effective reducing agent for the green synthesis of silver nanoparticles (AgNPs). It was further hypothesized that both the entire fraction (WSF) and the < 10 kDa fraction AgNPs would augment the therapeutic effects of kefir, particularly its antimicrobial activity.

Assessing Glibenclamide's efficacy on functional recovery in aneurysmal subarachnoid hemorrhage: A meta-analysis of randomized controlled trials.

Introduction: Glibenclamide, a sulfonylurea receptor 1 (SUR1) inhibitor initially developed for diabetes, has shown potential in reducing cerebral edema and neuroinflammation. This study evaluates its efficacy in improving functional outcomes and reducing complications in aSAH.

Methods: Databases including PubMed, EMBASE, and Web of Science were searched for RCTs assessing Glibenclamide's effects in aSAH.