Efficacy of curcumin supplementation for the treatment and prevention of pouchitis after ileal pouch-anal anastomosis: a randomized controlled trial.

Background: Pouchitis is the most common complication after ileal pouch-anal anastomosis (IPAA) for ulcerative colitis. Induction and maintenance of remission is a crucial therapeutic goal. We investigated curcumin's efficacy in treatment of pouchitis.

[Spatio-temporal Characteristics and Obstacle Factors of the Coupling Synergy Between New-type Urbanization and Low-carbonization of the Living Energy Consumption of Urban Residents].

Clarifying the dynamics and mechanism of the coupling and coordination relationship between new-type urbanization and the low-carbonization of the living energy consumption of urban residents can provide basic data and theoretical support for the national low-carbon economy and other high-quality development strategies from the perspective of urbanization. The entropy method, coupling coordination model, kernel density estimation, and obstacle model were used to investigate the spatial and temporal characteristics, coupling coordination, and obstacle factors of the two systems of China's new-type urbanization and the low-carbonization of the living energy consumption of urban residents from 2005 to 2021. The results showed that： ① The overall level of new-type urbanization and low-carbonization of the living energy consumption of urban residents showed an upward trend, and both had obvious spatial differentiation characteristics.

Risk Factors Analysis and Predictive Model Construction for Autoimmune Gastritis: A Nationwide Multicenter Case-Control Study in China.

Objective: Here, we ascertained the clinical characteristics of Chinese patients with autoimmune gastritis (AIG) and determined the correlation of dietary and lifestyle factors with AIG occurrence and development to establish a noninvasive predictive model for AIG.

Methods: In this case-control study, we enrolled 479 patients from seven independent centers nationwide in China; of them, 279 had AIG, 112 had chronic atrophic gastritis mostly in the antrum, and 88 had chronic nonatrophic gastritis. Their clinical and lifestyle data were systematically collected and analyzed.

Case Report: Identification of a novel fusion co-existing with fusion in papillary thyroid carcinoma.

fusions are validated oncogenic drivers of various adult and pediatric tumor types, including thyroid cancer, and serve as a therapeutic target. Recently, tropomyosin receptor kinase (TRK) inhibitors, such as entrectinib and larotrectinib, display promising therapeutic efficacy in -positive solid tumors. Although some fusion partners have been identified in thyroid cancer, the spectrum of fusion is not fully characterized.

Clinical presentations of gastric small gastrointestinal stromal tumors mimics functional dyspepsia symptoms.

Aim: To explore whether clinical presentations of gastric small gastrointestinal tumors (GISTs) mimics gastrointestinal dyspepsia symptoms.

Methods: The endosonographic data of 167 patients who underwent endoscopic submucosal dissection at the Tianjin Medical University General Hospital, China between 2009 and 2011 were analyzed. GISTs and leiomyomas had a similar intragastric distribution and similar locations within the gastric wall.