Ambipolar ohmic contact to silicon for high-performance brain-inspired image sensors.

Recently, ambipolar semiconductor devices have excelled in developing programmable photodiodes for brain-inspired image sensors, offering energy, speed, and security gains. However, the lack of mature processing techniques makes their manufacture challenging, and the often-adopted Schottky contacts limit their performance. Although CMOS technology is successful in integrated circuits, the employed ohmic contacts can only transport one type of carriers, failing to meet the requirement of electrons and holes working simultaneously in ambipolar devices.

Integrated [F]FAPI-42 PET/MR improves diagnostic accuracy in breast cancer: comparison with simultaneously acquired breast MRI.

Purpose: This study assessed the diagnostic efficacy of fluorine-18-labeled fibroblast activation protein inhibitor 42 ([F]FAPI-42) PET/MR versus simultaneously acquired breast MRI in identifying primary breast lesions and axillary lymph node metastases.

Methods: A prospective study enrolled 64 women with BI-RADS 4 or 5 lesions identified through mammography or ultrasound. All participants underwent contrast-enhanced [F]FAPI PET/MRI scans of the breast.

Binary Neural Network Based on a Programmable Graphene/Si Schottky Diode for In-Sensor Processing Image Sensors.

Recent advancements in in-sensor computing technology have demonstrated significant advantages in time latency and energy efficiency in visual information processing through device-level integration of photosensing and neuromorphic computing. However, current implementations face challenges due to their single-layer architecture, creating an urgent demand for the development of devices that integrate front-end in-sensor processing with back-end computing layers. Here, we report a programmable graphene/Si Schottky diode (PGSSD) featuring gate-voltage-programmed photoresponsivity and rectification direction.

Programmable Optical Encryption Based on Electrical-Field-Controlled Exciton-Trion Transitions in Monolayer WS.

Optical encryption is receiving much attention with the rapid growth of information technology. Conventional optical encryption usually relies on specific configurations, such as metasurface-based holograms and structure colors, not meeting the requirements of increasing dynamic and programmable encryption. Here, we report a programmable optical encryption approach using WS/SiO/Au metal-oxide-semiconductor (MOS) devices, which is based on the electrical-field-controlled exciton-trion transitions in monolayer WS.

Preliminary study on the short-term changes of pulmonary perfusion after a single balloon pulmonary angioplasty in patients with chronic thromboembolic pulmonary hypertension.

Background: Little is known about immediate responses of blood perfusion to the balloon pulmonary angioplasty (BPA) procedure.

Objectives: To investigate the changes in pulmonary perfusion of balloon-dilated vessels and untreated vessels with before, immediately after a single BPA and at follow-up.

Design: Retrospective single-center cohort study.

Facile Solid-State Synthesis to In Situ Generate a Composite Coating Layer Composed of Spinel-Structural Compounds and LiPO for Stable Cycling of LiCoO at 4.6 V.

Due to its high energy density, high-voltage LiCoO is the preferred cathode material for consumer electronic products. However, its commercial viability is hindered by rapid capacity decay resulting from structural degradation and surface passivation during cycling at 4.6 V.

Conformal Coating of a High-Voltage Spinel to Stabilize LiCoO at 4.6 V.

The ever-growing demand for portable electronic devices has put forward higher requirements on the energy density of layered LiCoO (LCO). The unstable surface structure and side reactions with electrolytes at high voltages (>4.5 V) however hinder its practical applications.

Raising the Intrinsic Safety of Layered Oxide Cathodes by Surface Re-Lithiation with LLZTO Garnet-Type Solid Electrolytes.

Battery safety concerns are becoming more and more prominent with the increasing demands of lithium-ion batteries (LIBs) with higher energy density. The greatest threat to battery safety derives from the easy release of oxygen from the high-capacity layered oxide cathodes at highly delithiated states and subsequent exothermic reactions with reductive agents in batteries. Herein, it is demonstrated that solid electrolyte Li La Zr Ta O (LLZTO) can supply lithium ions to re-lithiate the charged LiCoO at elevated temperatures.

Clinical Utility of F-18 Labeled Fibroblast Activation Protein Inhibitor (FAPI) for Primary Staging in Lung Adenocarcinoma: a Prospective Study.

Purpose: The purpose of this study was to compare the primary staging of F-18 labeled fibroblast activation protein inhibitor ([F]F-FAPI) with that of F-18 labeled fluordesoxyglucose positron emission tomography/computed tomography ([F]F-FDG PET/CT) in patients with lung adenocarcinoma (LAD).

Procedures: We prospectively analyzed the images of LAD patients who underwent [F]F-FAPI and [F]F-FDG PET/CT between May 2020 and August 2021. [F]F-FAPI and [F]F-FDG uptakes were compared using the paired samples t test, and lesion numbers were compared using the Wilcoxon signed-rank test.

Ruthenium-Catalyzed Reductive Cleavage of Unstrained Aryl-Aryl Bonds: Reaction Development and Mechanistic Study.

Cleavage of carbon-carbon bonds has been found in some important industrial processes, for example, petroleum cracking, and has inspired development of numerous synthetic methods. However, nonpolar unstrained C(aryl)-C(aryl) bonds remain one of the toughest bonds to be activated. As a detailed study of a fundamental reaction mode, here a full story is described about our development of a Ru-catalyzed reductive cleavage of unstrained C(aryl)-C(aryl) bonds.

Cobalt-Catalyzed Intramolecular Alkyne/Benzocyclobutenone Coupling: C-C Bond Cleavage via a Tetrahedral Dicobalt Intermediate.

A Co(0)-catalyzed intramolecular alkyne/benzocyclobutenone coupling through C-C cleavage of benzocyclobutenones is described. Co(CO)/P[3, 5-(CF)CH] was discovered to be an effective metal/ligand combination, which exhibits complementary catalytic activity to the previously established rhodium catalyst. In particular, the C8-substituted substrates failed in the Rh system, but succeeded with the Co catalysis.

"Cut and Sew" Transformations via Transition-Metal-Catalyzed Carbon-Carbon Bond Activation.

The transition metal-catalyzed "cut and sew" transformation has recently emerged as a useful strategy for preparing complex molecular structures. After oxidative addition of a transition metal into a carbon-carbon bond, the resulting two carbon termini can be both functionalized in one step via the following migratory insertion and reductive elimination with unsaturated units, such as alkenes, alkynes, allenes, CO and polar multiple bonds. Three- or four-membered rings are often employed as reaction partners due to their high ring strains.

Highly Diastereoselective α-Arylation of Cyclic Nitriles.

A highly diastereoselective α-arylation of cyclic nitriles has been developed via a Negishi cross-coupling of commercially available aryl, heteroaryl, and alkenyl halides with cyclobutyl nitriles in the presence of tetramethylpiperidinylzinc chloride lithium chloride (TMPZnCl•LiCl) and catalytic XPhos-Pd-G2. A variety of electronically diverse electrophiles were well tolerated, and this chemistry was further advanced with application of both cyclopropyl and cyclopentyl nitriles.

Efficient Benzimidazolidinone Synthesis via Rhodium-Catalyzed Double-Decarbonylative C-C Activation/Cycloaddition between Isatins and Isocyanates.

The first decarbonylative cycloaddition of less-strained cyclic ketones (isatins) with isocyanates is reported. Initiated by C-C activation, this distinct [5-2+2] transformation provides a rapid entry to access various benzimidazolidinone derivatives, through which a wide range of isocyanates can be efficiently coupled with broad functional group tolerance. A modified one-pot process, combining Curtius rearrangement and C-C activation, was also achieved by using acyl azides as the starting materials.

Cyclobutenones and Benzocyclobutenones: Versatile Synthons in Organic Synthesis.

Cyclobutenones, four-membered ketones bearing an unsaturated carbon-carbon double bond, and their structural sibling benzocyclobutenones, possess unique reactivity. Owing to their inherent high ring strain, such structures readily undergo ring opening under a variety of conditions, including thermolysis, photolysis, and transition metal catalysis, to afford reactive intermediates that can be trapped with nucleophiles, dienophiles, and unsaturated bonds. Their electron-deficient enone moieties are good electrophiles for facile nucleophilic addition.

Rh-catalyzed Reagent-Free Ring Expansion of Cyclobutenones and Benzocyclobutenones.

Here we report a reagent-free rhodium-catalyzed ring-expansion reaction via C-C cleavage of cyclobutenones. A variety of poly-substituted cyclopentenones and 1-indanones can be synthesized from simple cyclobutenones and benzocyclobutenones. The reaction condition is near pH neutral without additional oxidants or reductants.

Concise Synthesis of Functionalized Benzocyclobutenones.

A concise approach to access functionalized benzocyclobutenones from 3-halophenol derivatives is described. This modified synthesis employs a [2+2] cycloaddition between benzynes generated from dehydrohalogenation of aryl halides using LiTMP and acetaldehyde enolate generated from -BuLi and THF, followed by oxidation of the benzocyclobutenol intermediates to provide benzocyclobutenones. The [2+2] reaction can be run on a 10-gram scale with an increased yield.

Divergent syntheses of fused β-naphthol and indene scaffolds by rhodium-catalyzed direct and decarbonylative alkyne-benzocyclobutenone couplings.

A tunable rhodium-catalyzed intramolecular alkyne insertion reaction proceeding through the CC cleavage of benzocyclobutenones is described. Selective formation of either the direct or decarbonylative insertion product can be controlled by using different catalytic systems. A variety of fused β-naphthol and indene scaffolds were obtained in good yields with high functional group tolerance.